A thrombless gel is an antithrombotic drug intended for external use. It looks colorless( sometimes with a light yellow tinge), transparent, with a subtle smell of alcohol.
Available in aluminum tubes. The main active substance of the drug - heparin sodium - is contained in the amount of 1000 IU or 0.00833 g per 1 g of gel.
Also the preparation includes auxiliary substances:
Trombless Gel belongs to the category of anticoagulants of direct action.
The main component of the gel - heparin - has anti-edematous, antiproliferative, antithrombotic and anti-inflammatory effect.
It suppresses thrombin activity, reduces the risk of platelet adhesion. Improving the exchange and microcirculation in tissues, heparin quickly eliminates blood clots, resolves hematomas, restores the patency of blood vessels and reduces swelling.
The drug significantly reduces the intensity of pain, which is a big plus.
Active components of the drug enter the bloodstream in a small amount, so do not lead to systemic action. Heparin accumulates in the blood gradually and after 8 hours reaches its maximum concentration.
Its excretion from the body is carried out mainly by the kidneys after 12 hours.
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The preparation Trombless gel is prescribed for the following diseases and conditions:
The preparation Trombless gel is not appointed in the following cases:
Heparin is an anticoagulant of direct action. It lowers thrombin activity, thereby reducing clotting and preventing the formation of blood clots.
This is due to the fact that heparin binds to antithrombin III and blocks the passage of prothrombin into thrombin.
The active ingredients of the drug lower the activity of the hyaluronidase enzyme and reduce the adhesion of platelets to the vascular wall and to each other. Thanks to the antiseptic spirit basis, a cooling effect is created, which eliminates pain and heaviness in the legs.
The drug is available in the form of a gel in aluminum tubes of size 10, 20, 30, 40 and 50 g.
. The tube is punctured with a spike located on the back of the lid and then applied to the skin.
This is done this way: the skin is squeezed out a strip from 3 to 10 cm and gently rubbed with massage movements.
The duration of therapy also depends on the disease and the degree of its neglect, but on average it takes about a week. When thrombosis of hemorrhoidal veins for treatment use pads or rectal tampons with a gel.
Overdose of Trombless gel is practically impossible, since the drug is used topically, and heparin is absorbed into the blood in very small amounts.
However, with the occasional use of the gel inside, a digestive disorder is possible. In this case, standard procedures are used to purify the gastrointestinal tract. Antidote of heparin is protamine sulfate.
For prolonged treatment, redness of the skin or itching may be present on the site of application of the gel. If they do not pass, temporarily stop treatment and consult a doctor.
When applying gel to the skin, it is not recommended to immediately use a pressure bandage, as this will increase the absorption of heparin into the blood.
The drug is not recommended for use in disorders of the liver and kidneys, as these organs are responsible for processing and removing the medicine from the body. There are no data on the interaction of the drug with alcohol.
medications Applying the gel together with other oral anticoagulants may increase the risk of bleeding.
With the simultaneous administration of ergot alkaloids, ethacrynic and nicotinic acid, cardiac glycosides, tetracycline, antihistamines, the effectiveness of heparin decreases.
Interacting with ibuprofen, phenylbutazone, indomethacin, acetylsalicylic acid, dextran, heparin, on the contrary, increases its effectiveness.
The use of a gel for children raises some concerns because of the lack of clinical data in pediatric practice.
However, given the poor absorption of the active substances of the gel into the blood, it does not carry much danger.
In pregnancy and lactation, the drug can be used in the following diseases:
Reviews of doctors and patients taking Trombles gel.
Thrombless gel is a good remedy for injuries, bruises, phlebitis, at the initial stage of varicose veins. With advanced varicose veins, it does not work. Varicose veins should be removed surgically.
A very common problem during pregnancy is hemorrhoids. For treatment, I recommend a heparin ointment or a thrombless gel containing heparin. They are effective and practically safe.
If my legs are swollen, I prescribe the Trombles gel. He well anesthetizes and relieves swelling.
First used it to relieve pain at the site of bruises and resorption with hematomas, and then began to be used for varicose veins. It's good.
This gel is used by my mother. She has constant pain in her legs, varicose veins. He says that it helps, and even the gel has a pleasant smell and is quickly absorbed into the skin.
To me, Trombles gel works well for oedemas, but they say that those who have strong leg problems may not be suitable.
Advice from patients:
Given the feedback from doctors and patients, the Trombless gel has both advantages and disadvantages.
This drug is good for swelling of the legs, quickly relieves pain, reduces the severity of bruises, is suitable as a preventive measure of varicose veins. As many people note, unlike analogues, the medicine has a relatively low price.
However, the gel does not cure completely of varicose veins. This is due to the fact that varicose disease is difficult to treat and requires stronger drugs.
Some patients report an allergic reaction to the drug, but this is difficult to attribute to shortcomings, as it depends on the individual tolerability of the active components of the gel.
The drug is available in aluminum tubes from 10 to 50 g, but the most widely used tubes are 30 g and 50 g.
Price Trombles gel 1000ED / g 30 g varies from 197 to 280 rubles., 1000ED / g 50g - from 280up to 380 rubles .depending on the pharmacy and the region.
The shelf life of the Tromblesse gel is 3 years, provided it is stored in a dry, warm place.
The thrombless gel belongs to OTC drugs, so it is released at the pharmacy freely.
Today, there are several analogues with the same active substance as the Trombles gel.
From foreign it is worth noting the Italian remedy Lyoton and the German Wyatromb and Trombofob. To drugs of domestic production with a similar effect include Lavenum gel and Heparin-Acrigel.
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