Features of the use of the drug for the sclerotherapy of veins Ethoxysclerol

Ethoxysclerol is a specific drug with a venosclerosis effect. It is endowed with a local anesthetic effect. This drug is widely used to counter varices.

The drug is used exclusively by the doctor in charge. The presence of special remarks and a whole list of side effects and contraindications makes it very dangerous for independent use.

Note that the form of the release of ethoxiclerol is a solution for injection.

Contents

  • Pharmacological properties of
  • Application of
  • Medication and dosage parameters
  • Contraindications and side effects of
  • Special remarks

Pharmacological properties of

Ethosclerol is a vivid representative of venosclerosis. This drug, among other things, provides a local anesthetic and spermatocidal effect and effect. As for the latter, we are talking only about the local contraceptive effect.

How does it work? Is it necrosis? The ingestion of the drug into the patient's body provokes protein denaturation, since the agent as a whole is a detergent.

As for intravenous administration, the drug contributes to damage to the vascular endothelium, creating a sclerosing effect. Note that the latter effect is achieved only if there is a fall in the vein and the subsequent contact between its walls. After sclerosing, a fibrous scar is formed.

The drug is aimed at stimulating the accelerated creation of a thrombus, which forms over a period of 7 days.

It is also used for hemorrhoids of various forms. After the agent is in the lumen of the hemorrhoidal node, the effective substances produce a process of protein denaturation in the cells of arteriovenous shunts. It is this effect that provokes the formation of thrombosis of the node, and then - the obliteration in the lumen called.

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Another option - the introduction of the drug inside the tissue, when it is in the wall of the stomach and esophagus. The main, actually - and the first - result will be the appearance of edema of local paravalous nature. Already after it is formed scarring in the field of paravalous fiber, as well as compression of varicose-dilated veins.

Use of

The ethoxysclerol has a very extensive spectrum of action. This drug is actively used for the purpose of sclerosing.

The reason for using the drug are:

  • varicose-extended veins ;
  • hemorrhoidal nodes and telangiectasia ;
  • varicose-dilated esophagus and stomach veins ( in particular - cirrhosis of the liver or portal hypertension of the non-hepatic form, in such situations resort to obliteration or parietal sclerosing);
  • instrumental endoscopic hemostasis ( observed with acute bleeding from varicose veins of the esophagus, gastroduodenal ulcer bleeding, complete portal vein thrombosis, shunt-thrombosis, the drug also helps in the period after the acute phase of the disease).

The market offers potential buyers a considerable number of analogues of Eosisislerol. Use of the drug can only be consultation with a doctor.

Dosage and dosage parameters of

There are several ways of taking ethosclerol. The first is intravenous( B \ in).And in addition - paravasal( submucous or subepithelial).The dose in such cases is 2 mg( upper limit) with calculation for kg / day.

The process of sclerosing telangiectasias and veins associated with varicose veins is performed exclusively with a horizontal or elevated position of the leg within 45 degrees, and only in / in the way. To this end, a 0.5-3% ampoule solution is used.

The volume of the dose varies depending on the varicose extensions. If they are small, the single dose is 0.1 to 0.3 mL of the percentage solution;if the expansion is slightly larger, then the dose will be the same 0.1-0.3 ml, but already a one-percent solution of ethosclerol.

In situations with medium and large varicose dilutions, dosage: 0.5-1 ml;solution - 2-3%.If necessary, a dose of 2 ml can be used. Finally, the maximum dosage level is 2 mg / kg per day.

The following example - when varicose extensions are very extensive, the course of therapy will be divided into several stages.

The dose for telangiectasia of peripheral veins is 0.1 - 0.2 ml;the norm of the solution is 0.5%.

In the case of central vein telangiectasia, the dosage ranges from 0.1 to 0.2 ml;solution - one percent.

After injection, the patient should be placed with a pressure bandage for 30 minutes. This is done in order to prevent the process of recanalization due to the compression of the veins walls and to promote the formation of a fibrous scar.

If a patient suffers from telangiectasia, the bandage should be worn for two to three days. As for the remaining cases - for 5 or even 7 days.

Often, doctors resort to the use of compression with elastic bandages or medical stockings of the second or third class.

This practice is used in the presence of pronounced varicose veins. It is not mandatory, only recommended. Compression is used for 4-6 weeks.

Contraindications and side effects of

Individual patients may experience hypersensitivity to certain components of this drug. In addition, in no case can not prescribe Etoosclerol to patients who have observed:

  • state of shock;
  • prescribed strictest bed rest;
  • period of pregnancy, especially in the first trimester and after 36 weeks( allowed with acute bleeding);
  • lactation period.

With caution, the agent must be assigned to different patient categories. A separate group of risk is the elderly, suffering from obesity, experiencing swelling in the extremities.

The drug is very specific, if we consider it through the problem of side effects. This issue is very well studied and analyzed.

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So, it should be noted that after taking the drug, in the first place, there may be reactions of an allergic nature. Most often they will be expressed in the form of anaphylactic shock and skin rash.

The process of sclerosing varicose-dilated esophagus veins in other patients can provoke other, more complex reactions.

In a certain group of patients, there are collapses, dizziness, visual disturbances, difficulty breathing, nausea, "metallic" taste, and the like. All these complications should be taken into account by the attending physician.

Symptom of overdose will be necrosis( with paravasal injection).In this case, you will need treatment, which will consist in the introduction of a 1% procaine solution( 0.5-2 ml dose) or 0.95% NaCl + hyaluronidase solution( dose - 5-20 ml).

Special remarks

This is not permitted for intravarietal administration of escusclerol. In addition, if the preparation is to be used in the area of ​​the ankle and ankle, the dosage should be strictly limited and the solution 0.5%.

There is a picture of the development of arrhythmogenic effect in a situation of simultaneous use of ethosclerol and anesthesia.

It is also particularly important to apply the drug in the case of older people. If such patients have a severe general condition or limited ability to move, then use the drug with extreme caution.

Specificity of varicose veins is such that the disease manifests itself in a more mature age. In this regard, there is not the slightest experience of using the drug to treat children.

A separate note on bad habits. In the course of 48 hours before and after sclerotherapy, it is strictly forbidden to use tobacco products and alcoholic beverages.

If the drug was used during lactation, then breastfeeding should be suspended for 2-3 days.

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  • Mar 16, 2018
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