Venotonizing agent Daflon: instructions and references

Daflon 500 is one of the most commonly used drugs for the treatment of varicose veins, hemorrhoids, venous insufficiency and other forms of circulatory disorders.

The preparation is manufactured by the French pharmaceutical company Servier and belongs to the pharmacological group of microcirculatory and angioprotector correctors.

Thanks to this preparation, the structure of the venous wall is stabilized, its tone is increased, blood flow is accelerated and the blood supply of the diseased part of the vein decreases.

In simple words, everyone knows that blood moves through the veins up and down. Moving downwards helps the laws of gravity, but the heart and muscles of the legs, as well as the venous valves, do not allow it to move up, preventing the flow of blood from slowing down.

So, when the vein loses its elasticity and stretches, the valves stop closing, and as a result, blood circulation is disrupted.

Vienna expands even more, and the problem is aggravated by the development of compli

cations in the form of trophic ulcers, inflammation, edema and severe pain. It is Daflon who is able to stop the destructive process and restore the normal functioning of blood vessels.

The preparation is in the form of capsular tablets coated with an orange-pink film membrane. Each tablet of this medication contains 500 mg of the active substance of plant origin, which belongs to the group of flavonoids - diosmina in a dosage of 450 mg and hesperidin in a dosage of 50 mg.


  • Pharmacological properties and mechanism of action
  • Indications for use
  • Dose and dosage regimen
  • Special instructions for use of the drug
  • Side effects and overdose
  • Assignment to special patient groups
  • The word to consumers
  • Acquisition issue

Pharmacological properties and mechanism of action

The main active ingredient of Daflonis diosmin. As shown by experimental studies, it is more effective in combination with a flavonoid such as hesperidin, which is an auxiliary component of this drug.

Thanks to this unique combination of diosmin with hesperidin it is possible:

  • to reduce the permeability and fragility of the walls of capillary vessels;
  • reduce blood viscosity;
  • improve lymphatic fluid outflow;
  • to increase the elasticity and tone of venous vessels;
  • to reduce the painful dilatability of veins;
  • to prevent sclerotic vascular lesions;
  • improve capillary blood flow.

Both components of the drug reduce the viscosity of leukocytes, preventing them from adhering to the walls of the vessels. Thanks to , this reduces the risk of getting blood into the parainous tissues.

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As a result, it is possible to avoid the appearance of red spider webs on the skin of the legs, as well as to improve oxygen diffusion in skin tissues adjacent to the problematic areas of the veins.

The action of the drug perfectly suppresses all the unpleasant symptoms of chronic venous insufficiency, which can be felt by swelling, cramps, pain, fatigue, tension and heaviness in the legs.

Daflon tablets are also effective in the treatment of acute and chronic hemorrhoids. They relieve the pain syndrome, reduce swelling and stop bleeding as early as the second day after the beginning of admission.

This is what makes it possible to improve the patient's quality of life and avoid excessive intake of painkillers.

According to patients, the Daflon 500 accelerates the healing of surgical sites and reduces the risk of postoperative bleeding.

The active ingredients of the preparation are micronized, so the drug is rapidly adsorbed in the gastrointestinal tract. The peak concentration of the substance in the blood is observed as early as 15 minutes after oral administration.

Then it begins to gradually decline, but after 4 hours a new surge in the level of blood levels of active substances is observed. After 24 hours the drug is completely removed from the blood, with most of it excreted with feces, and only about 14% of the substance leaves the urine.

Indications for use

The agent is indicated for the symptomatic treatment of the following diseases:

  • chronic venous insufficiency of the vessels of the lower limbs;
  • lymphatic insufficiency;
  • acute and chronic hemorrhoids.

The main symptoms of chronic venolymphatic insufficiency are: swelling, pain, tension and heaviness in the legs, as well as lymphedema, trophic ulcers and nocturnal cramps.

As for the treatment of hemorrhoids, the use of the drug is usually a supplement to the main treatment.

It is not recommended to take the drug to patients who have an individual intolerance to any of the components of this drug, as well as during breastfeeding.

Dosage and Administration Regimen

Daflon should be taken with meals. The scheme and dosage of taking capsules depends on the form and nature of the disease.

For chronic lymphovenous insufficiency, as well as for the prevention of recurrences of chronic hemorrhoids, one tablet should be taken twice a day.

After a week, you can go to take 1 tablet a day. The period of therapy depends on the complexity of the disease, but the average duration of taking tablets is 2 - 3 months.

In acute hemorrhoids, a short course of therapy is usually carried out according to this scheme:

  • 6 tablets per day for 4 days;
  • 4 tablets per day for the next 3 days.
In case if after a week of taking the drug does not bring relief, it is necessary to conduct a thorough proctologic examination and revise the treatment regimen.

Special instructions for use of the drug

During the intake of tablets, avoid prolonged exposure to sunlight. It is also recommended to go for a walk and be sure to follow the mass of your body.

In special cases, it is necessary to wear a compression jersey that improves blood circulation in the lower limbs. It should always be remembered that in order to achieve maximum effect in the treatment of venous blood flow disturbance, it is necessary to carry out complex therapy.

That is, together with the reception of tablets it is recommended to lead a healthy lifestyle and follow all the recommendations of a doctor.

Side effects and overdose

Hypersensitivity to the components of the medication is extremely rare and can usually manifest as such by-effects:

  • problems with the gastrointestinal tract : nausea, vomiting, diarrhea or constipation accompanied by pains in the lower abdomen;
  • allergic rashes : dermatitis, urticaria;
  • Central Nervous System Disorders : weakness, headache, dizziness.

But in general, Daflon is tolerated well by patients, and even in the case of minor disorders, treatment should not be discontinued. As for the overdose, the description of the drug does not contain any information on this case.

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Assignment to special patient groups

To date, there is no information about the side effects of taking the drug in pregnant women. Therefore, it is necessary to apply it during pregnancy only if there is no other way for the mother, and the expected positive effect exceeds the possible risk for fetal development.

There is no clinical data on the ingestion of the drug into breast milk and its effect on the baby, therefore, during the period of breastfeeding, the treatment with pills must be stopped.

In pediatrics, the drug is not used, as there is no information about treatment for children.

Daflon absolutely does not affect the speed of the reaction. However, in case of side effects, while driving, you need to be more careful and cautious.

The word to consumers

Reviews of patients who have already had the occasion to apply Daflon in practice.

When the first unpleasant sensations in the legs began to appear, I did not attach any importance to them. But my feet began to pour like pads, painful discomfort appeared in my legs, and a red mesh appeared on my shin, I realized that I could not do without the help of a specialist.

The therapist prescribed Daflon 500 for me. I underwent a two-month course of treatment according to the scheme of two tablets a day. Honestly, I did not even expect such an effect. Problems with the legs have gone completely, do not hurt or swell. I can not believe that pills can do such miracles.

Svetlana, 45 years old

For a long time I suffer from chronic hemorrhoids, sedentary work, severe birth and heredity. At the first unpleasant symptoms of an exacerbation, I start to drink tablets Daflon 500.

The medicine helps instantly, but the main thing for a long time relieves of all unpleasant symptoms of this disease.

Nina, 38 years

Question of acquisition

The drug is dispensed in the pharmacy network only by prescription. Keep Daflon in a dry and dark place at a temperature of no higher than 30 ° C.Shelf life of the tablets is 4 years.

In addition to Daflon, there are drugs that have the same composition and have similar therapeutic effects. These include:

  • Venarus;
  • Venolife;
  • Troxevasin;
  • Venoruton;
  • Hepatrombin;
  • Detralex.

All of these drugs are cheaper analogs to the French drug Daflon. In theory, they all do not differ absolutely nothing, but in practice it is difficult to establish a difference, since there is no information about the technological nuances of their production.

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  • Mar 01, 2018
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