Varicose veins and thrombosis - this is the main problem of modern society. Therefore, for the treatment of these phlebological diseases, more and more new drugs are being developed every year.
One of the effective means for the treatment of varicose veins, thromboembolism, thrombosis and other venous diseases is the preparation Flenox, but before you start using it for therapy it is worthwhile to carefully study the instruction and advice on its use.
Flenoks refers to the group type of the anticoagulant drugs. The main component of the drug
In this case, the activity of the anticoagulant type is higher than the activity of the antiplatelet type, the ratio of these indices is 1 to 3.6.
Flox has almost no effect on activated thromboplastin time. When used in therapeutic doses, prolongation of APTT occurs, as a result of which the residual antithrombin activity is reflected.
When using the drug in therapeutic dosages APTTV can be prolonged, its excess can be almost 1.5-2.2 times the control time of the maximum level of activity.
When the drug is administered subcutaneously, the level of bioavailability of the main component of the drug is 100%.The highest plasma concentration occurs 3-4 hours after the administration of the agent.
The main metabolism of the main component of the drug is observed in the liver. It is excreted by the kidneys or through the liver. The half-life of enoxaparin during a single administration is achieved after 4 hours, with subsequent administration - 7 hours.
Flenox contains an active ingredient - enoxaparin.
Depending on the dosage of the medicine, the level of this component is different. The preparation with dosages of the main component of 0.2 ml, 0.4 ml, 0.6 ml and 0.8 ml is produced.
Additional components are water for injection.
Produced in syringes in the form of a solution for subcutaneous injection. In appearance it is a clear solution, sometimes it can have a yellow color.
Flenox is assigned at the following indications:
According to the instructions Flenox can not be used for the following indications:
In addition, the drug can not be used in the following diseases:
Depending on the situation, various schemes of application of Flenox are used.
During surgery, patients who have a moderate risk of blood clots and in patients without the risk of thromboembolism, the drug should be administered subcutaneously at a dose of 20 mg once every 24 hours.
Patients who are prone to thromboembolism, Flenox should be administered subcutaneously at a dose of 40 mg once every 24 hours. In general surgery, the first dose of medication is administered 4 hours before surgery, in orthopedic surgery 12 hours before surgery.
The average course of therapy lasts from a week to 10 days. In orthopedics the agent is prescribed in a dosage of 40 mg once every 24 hours, the period of therapy lasts about a month.
Patients on bed rest, should be administered Flenox subcutaneously at a dosage of 40 mg once every 24 hours.
The drug should be used about 6 days, the course of therapeutic therapy lasts no more than 2 weeks.
The drug is administered subcutaneously once a day at a dosage of 1.5 mg per kilogram of body weight or twice a day at a dosage of 1 mg per kilogram every 12 hours.
How the Kleksan injection is injected( full analog of Flenox):
The most frequent after application of the drug, the following side effects occur:
During pregnancy, the drug is prescribed only for life indications, while the doctor must be constantly monitored.
Do not use this product on pregnant women who have cardiac valve prosthetics. It is not recommended to use the drug during spinal and epidural anesthesia.
If you need a drug during lactation, then for the period of therapy it is necessary to completely abolish breastfeeding.
For children under 18, the use of the drug is contraindicated. This is due to the fact that there is no data on how the medicine affects the children's organism.
It is not advisable to use Flenox in conjunction with the following types of medications:
Having studied the opinion of the medical community and the patients' feedback, it is possible to obtain even more useful and important information about Flenox.
Flenox is a remedy that shows itself well enough in the treatment of various venous diseases - varicose veins, thromboembolism and deep vein thrombosis.
No negative reactions were observed by my patients during the entire period of application of this agent. However, in any case, it is worth to pre-examine and consult a doctor.
I often assign my patients to Flenox at the risk of thrombosis and / or thromboembolism. For all my practice of using this drug I can note that in all cases the remedy helped.
Many patients reported improvements from the second use of the drug.
For a long time suffered from thrombosis. Frequent pains and inflammations - these conditions I almost always had.
After another examination, the doctor appointed me a drug Flenox. I was injected intramuscularly at a dosage of 20 mg once a day for 10 days. I noticed that on day 3, pain and inflammation stopped worrying me, and after a full course I felt much better.
Svetlana, 57 years old
Deep vein thrombosis is a disease that I suffered for 8 years. After consulting the doctor appointed the drug Flenox, for a start he prescribed me to use it for 5 days in a dosage of 20 mg.
I noticed improvements already in 2 times the application. After a 5-day course of treatment, the doctor extended the treatment for another 5 days. Surprisingly, after a full course of treatment I felt much better!
Sergey, 49 years
Depending on the dosage, the price of Flenox is:
Also in the absence of the drug, its analogs may be offered:
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