Candles Geposilon for the treatment of hemorrhoids and other proctologic diseases

According to different data from hemorrhoids, from 50% to 85% of the inhabitants of the earth are suffering. The disease can appear at any age, including even in young children. In babies, it happens because of the delay in the chair and the habit of sitting on the pot for a long time.

In adults, the main causes of the disease are inactivity, problems with defecation, abuse of alcoholic beverages, spicy and salty foods.

At the first and second stages, the disease can be cured with local medicines, for example, candles Geposolon, the Russian company Altpharm.


  • Product description
  • Pharmacodynamics and Mechanism of Action
  • pharmacokinetics of drugs
  • When prescribed suppositories
  • undesirable side reactions
  • When the use should refrain
  • Assigning specific patient groups
  • Regimen
  • Purchase and storage conditions
  • Opinion patients
  • Says
  • Specialist What can replace medicine

Description of the preparation

Gebreolone is a combined drug w

ith antithrombotic,venosclerosis and anti-inflammatory effect.

In its composition, the agent contains the following active substances:

  • sodium heparin;
  • prednisolone;
  • lidocaine hydrochloride.

Produced in the form of rectal suppositories of white or slightly yellowish color.

Pharmacodynamics and mechanism of action

The therapeutic effect is due to the substances included in the preparation:

  1. Heparin prevents thrombogenesis, prevents platelet aggregation, eliminates edema, accelerates the healing of damaged tissues, reduces the number of exacerbations of the disease. Heparin inhibits the reaction of blood coagulation and thrombus formation. In addition, it affects the inner layer of blood vessels, eliminates edema, and removes inflammation.
  2. Prednisolone refers to synthetic glucocorticosteroids with an average duration of action. It disrupts the synthesis of inflammatory mediators, reduces the release of exudate, eliminates the interaction of macrophage cells, target cells, cytokines involved in the development of allergies. Thus, prednisolone has anti-inflammatory, anti-exudative and antihistamine effect, eliminates the inflammatory process, as well as itching, burning, soreness in the perianal zone.
  3. Lidocaine prevents pain signals from nerve fibers. It is he who has a local analgesic effect. Thanks to this combination, the drug eliminates all the symptoms of hemorrhoids.

Pharmacokinetics of the drug

Heparin and prednisolone are rapidly absorbed when inserted into the anus, transported to the intestinal wall and then delivered to the liver where they are metabolized.

Derived as metabolites in the urine. The half-life of heparin is 60-90 minutes, prednisolone from 18 to 36 hours.

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Lidocaine is rapidly adsorbed through the rectal mucosa. Its maximum concentration in the blood is observed after 2 hours. Lidocaine undergoes metabolic reactions in the liver. It is excreted through the intestines and kidneys. T ½ lasts 1-3 hours.

When prescribing

suppositories The drug is successfully used in the following proctologic diseases:

  • external and internal hemorrhoids;
  • thrombosis and inflammation of the hemorrhoidal veins;
  • fistula of the lower intestine;
  • eczema and cracks in the anorectal region;
  • itching and inflammation in the anus;
  • preparation for surgical intervention in the perianal region;
  • as part of complex treatment of thrombosed and operated hemorrhoids.

Adverse Reactions

Side effects from the drug are observed when it is used for more than 5 weeks and they are related to the action of prednisolone on the body that make up the drug.

Specifically observed:

  • from the side of the central nervous system : dizziness, trouble with sleep;
  • from the side of metabolism : increased sweating, hypocalcemia, hypokalemia;
  • from the cardiovascular system : arrhythmia, hypertension, bradycardia, changes in the electrocardiogram;
  • from the endocrine system : steroid diabetes, decreased adrenal function, Cushing's syndrome;
  • on lidocaine and heparin allergic reaction in the form of itching and irritation of the anorectal zone is possible.
If unwanted effects appear, stop using suppositories and contact your doctor for another treatment. Also it is necessary to address to the expert at absence of therapeutic action.

In case of accidental ingestion of suppositories, immediately wash the stomach and take the enterosorbent. Cases of overdose by suppositories during rectal administration are not described.

When to abstain from use

The drug has a number of contraindications:

  • individual intolerance;
  • infections of the anorectal zone( including tuberculosis, viral and mycotic diseases);
  • problems with blood coagulability, tendency to bleeding;
  • pregnancy and lactation;
  • children under 12 years.

Intended for special patient groups

Drug is not allowed for use in children who are under 12 years of age, as there is no data on the safety of the drug in pediatrics.

For the treatment of older children, the drug is used strictly according to the indications and under the supervision of a specialist.

The drug is contraindicated for use during childbearing and breastfeeding, as it contains a glucocorticosteroid prednisolone.

To date, there is no reliable data proving the safety of pharmaceuticals in this category of citizens.

The use of glucocorticosteroids orally during pregnancy can lead to fetal malformations, and when breastfeeding - to violations of adrenal function of the child.

Scheme of treatment

With internal hemorrhoids, the suppositories are inserted into the rectum 1-2 times a day. Doing this is desirable after evacuation of the intestine, in this case the effect of the drug will be maximum. Ointment Gebazalon is not released, but with external nodes you can also use candles.

With external hemorrhoids, the suppository is not completely inserted into the anus, it is necessary that its base be probed outside.

From the outside, the anus must be kept for 2-3 minutes with a gauze bandage during this time, the candle completely melts and has a pharmacological effect.

The course of therapy is 1 week, an expert can extend treatment up to 2 weeks.

Purchase and storage conditions

Average price of candles Gebazolon 160 rubles.

Suppositories are stored in a dark place at a maximum of +25 degrees.

Shelf life of the drug is 2 years, after which you need to stop using the drug. Since it not only can not act, but even harm health.

Opinion of patients

Nuances of using candles Gebryolone for the treatment of hemorrhoids can be determined by examining the patients' testimonials.

Our readers recommend!
For the treatment and prevention of varicose veins and hemorrhoids, our readers use the method first voiced by Malysheva. Having carefully studied it, we decided to offer it to your attention. Opinion of doctors. .. »

Work at me sedentary, therefore the hemorrhoids appear periodically. But the last time the pain was unbearable, and even bleeding every time after going to the toilet. I was very frightened and signed up for an appointment with the proctologist. The doctor looked and wrote out the candles of Gebryolon.

Already on the 5th day of using suppositories it felt much better. Shed hemorrhoids, bleedings have passed. Within 10 days of the disease, there is no trace left.

Rose, Zvenigovo

The first signs of hemorrhoids began during pregnancy, after the birth the disease intensified. I went to see the proctologist, he appointed Geispanol candles.

The pain went right away, it became easier after the first candle. Dissolve the suppositories quickly. And everything was fine, but on the fourth night I woke up from the severe, painful pain that I gave to my left arm. I thought that my heart would jump out of my chest, it lasted for about 5 minutes. Before that, my heart was not there.

Nina, Kazan

specialist says. Despite its high efficiency, the preparation of Gebreolone has a number of contraindications. In addition, the drug has many side effects, especially when applied for a long time( more than 1 month).

Therefore, when using a medicine, you need to be very careful and with the slightest deterioration in health immediately stop treatment and go to the hospital to adjust the method of therapy.

Do not use the drug during pregnancy because of the glucocosteroid content. Prednisolone penetrates the placental barrier and can have a negative effect on the fetus. During this period, it is better to use other drugs, for example candles with sea buckthorn oil or Natalsid.

It is also worthwhile to refrain from using the drug during lactation. Glucocoestroids penetrate into the mother's milk, can harm the baby. Therefore, it is worthwhile to either transfer the child to the mixture or refuse treatment with suppositories.

Self-medication with the drug is not permissible, especially for a long time. The drug is dispensed from the pharmacy strictly according to the doctor's prescription.

Sergey Vladimirovich, proctologist

How to replace the medicine

The analogues of the drug are:

  • Relief;
  • Ultraproject;
  • Proctosan;
  • Proctosedil;
  • Gepatrombin G.

Use Gezapolon candles instead of its candles only after consulting with your doctor.

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  • Mar 03, 2018
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