The drug of a wide profile of application Indovazin: exhaustive instruction

Gel Indovazin is a medicine that has antiphlogistic and angioprotective effects.

This is a complex preparation intended for surface use.

Indovazin helps to improve the condition of veins and small vessels and relieves inflammation when thrombophlebitis occurs.

Composition and form of release

The preparation consists of two main components: troxerutin and indomethacin, to which are added other auxiliarieswa.

Troxerutin is a bioflavonide related to angioprotective agents. Indomethacin acts as an analgesic and anti-inflammatory agent.

The drug is released as a gel for external use from yellow to yellow-brown. The number of active elements is:

• 30 mg troxerutin;
• 1 g of indomethacin;
• 20 mg of additional substances( ethanol, carbomer, macrogol, sodium benzoate and propylene glycol).

The gel is placed in small tubes of aluminum, with a capacity of 45 g. The preparation is packaged in cardboard packages. The medicine can be sold without a doctor's prescription. The period of the drug's suitability is two years, after which the ointment should be disposed of.

Pharmacological action of

The active active substance of the drug is troxerutin and indomethacin. The drug has such therapeutic effects on the body:

• anti-inflammatory effect;
• venotonic;
• decongesting action;
• decrease in temperature in the area of ​​inflammation;
• a change in the nutrition of disordered structures in the presence of venous insufficiency;
• decrease in the probability of switching erythrocytes among themselves;
• rapid regeneration of damaged structures;
• prevention of fragility of small blood vessels;
• prevents the narrowing of the passage of blood vessels by blocking certain biological active elements.

Pharmacokinetics of the preparation

The ointment base of the drug promotes the dissolution and release of troxerutin and indomethacin. The gel structure with the active substance is rapidly absorbed from the skin surface and has a therapeutic effect of the drug.

After absorption, high concentrations of the drug are formed in the parenteral tissue, close to therapeutic ones. At the same time, a small amount of active components of the drug penetrates the systemic bloodstream. The preparation practically does not bind to blood plasma proteins.

The main mechanism of action is to suppress the process of synthesis of prostaglandins, due to the reversible blockade of harmful substances.

When active substances enter the inflammation zone, they begin to exert a venotonic effect and reduce the permeability of the capillaries. In general, the medication slows inflammatory hydration and relieves swelling in the area of ​​inflammation.

The active substance of the drug blocks the venodilating effect of histamine, acetylcholine and bradykinin. They also relieve inflammation on perennial tissues and exert antiaggregatory action on them.

Indications for use

Indovazin is indicated for the occurrence of such diseases:

• varicose veins;
• acute and chronic polyarthritis;
• nerve inflammation and nerve plexus lesions;
• rheumatic soft tissue damage( bursitis, tendovaginitis and periarthritis);
• the presence of edema after dislocations, sprains and surgical interventions;
• inflammation of superficial veins;
• presence of postphlebitis;
• venous insufficiency of the legs;
• presence of radiculitis;
• trophic disorders due to chronic venous insufficiency;
• presence of post-traumatic hematomas;
• psoriasis accompanied by multiple joint injuries.

When a medicine is not used

The use of an indazine ointment is contraindicated in the following cases:

• hemorrhagic diathesis;
• hypersensitivity to medication;
• presence of gastric ulcer;
• violation of the mechanism of blood clotting;
• presence of leukopenia;
• is less than fourteen years old;
• pregnancy and lactation;
• presence of bronchial asthma;
• history of allergic rhinitis;
• compromised skin integrity;
• third trimester of pregnancy;
• of duodenal disease in the phase of exacerbation.

Indovazin is not recommended for use with other non-steroid medications and antibacterial drugs.

Instructions for use

How to use Indovazin - external.2 cm of the gel must be applied with rubbing movements. Multiplicity of application is about two to three times a day.

The course of treatment should last no more than ten days.

If during this time the patient does not observe any improvement, then this drug must be changed to another one. But it should be done only with the permission of the doctor.

The maximum applied amount of gel per day should not exceed a length of more than 20 cm.

Doses of the drug do not change, depending on the form in which the medicine is used( ointment or gel).

Overdose and additional indications

No overdose data are indicated in the medication instructions. With external application, overdose is almost impossible, since the composition of the medicament includes a minimum amount of active substances that can enter the bloodstream.

If the drug accidentally enters the body by ingestion, nausea and vomiting may occur. In this case, you should see a doctor to do a gastric lavage.

A high probability of overdose may occur when using analogues of the drug. Replacing the primary product with its analogue, you must first consult with your doctor.

If the course of treatment with Indovasin has exceeded ten days, then in some cases hepatoxicity, severe headache and even hemorrhage may occur. In such a case, it is necessary to monitor the platelet and leukocyte counts. With radiculitis and arthritis, the course of treatment is increased to fourteen days.

Side effects of

Basically, drug tolerance is considered good. Sometimes some local reactions may occur:

• increased sensitivity from the skin in the form of contact dermatitis;
• heat and burning at the place of application;
• redness and rash;
• itching.

Special instructions

Indovazin is not recommended for application to mucous membranes and open wounds. In the event of medication falling into the eyes or on a non- wound, the affected area should be washed with running water. You can also use a special saline solution.

When using the drug, remember that it contains additional substances such as sodium benzoate and propylene glycol, which can cause skin irritation.

The drug affects the ability to drive vehicles and control mechanisms. During the course of treatment with Indovazinom, you should not drink alcohol.

As for the interaction of the drug with other drugs, it should not be used simultaneously with corticosteroids, because of the possible occurrence of ulcerogenic effects.

Medication can not be used during pregnancy and lactation. If there is an acute need for a course of treatment, it is necessary to stop breastfeeding. It is prohibited to use the medicine for children who have not reached the age of fourteen.

Practical experience of using

We recommend to study the reviews of doctors and ordinary people to make your opinion about the preparation of Indovazin.

From all the reviews we can conclude that acting according to the instructions and recommendations of doctors, in most cases the drug has a put effect. Of the minuses, you can identify the presence of side effects, which are not so often manifested.

We go to the pharmacy

Indovazin gel and ointment are available in tubes of 20 and 45 g, the average price of the drug is 230 rubles.

The preparation should be stored with a tightly twisted cap in a dark place out of the reach of children. The temperature in the room during storage should not exceed 25 degrees. Shelf life of the drug is two years from the date of its manufacture.

Available in pharmacies without a doctor's prescription.

Indovazin has no structural analogues, as it has a unique composition of active substances. However, the drug has analogs for the pharmacological group:

• Agapurin;
• Venitan;
• Troxerutin;
• Thrombovar;
• Escuzan;
• Ralough;
• Antistax.