Thrombotic diseases are serious pathologies, the treatment of which should be started from the very first days of their appearance. One of the effective tools that is used in the treatment and prevention of venous thrombosis and thromboembolism is Anfiber.
Anfiber is an anticoagulant with a direct effect. This agent is included in the group of low-molecular-weight heparins( LMWH), with a molecular weight of 4,500 daltons. This drug has an antithrombotic effect.
The drug has a vigorous activity with respect to the factor Xa a
During the subcutaneous administration of the agent, it is rapidly and completely absorbed from the injection site. The maximum peak in activity of the main component of enoxaparin with respect to factor Xa occurs after 3-5 hours. This value corresponds to a concentration level of 1.6 μg / ml after the administration of 40 ml.
The liver metabolizes a small amount of enoxaparin, which forms low-activity metabolites.
The half-life of the drug lasts 4 hours. Its excretion occurs through urine in a pure state or in the form of metabolites.
Produced in the form of a solution for injection. In form it is a colorless liquid. In 1 ml of the solution for injection, 100 mg or 10,000 anti-Xa I enoxaparin sodium is included.
In pharmacies Anfiber is sold in the form of ampoules and syringes with the following volumes:
Anfiber is used for the following indications:
Anfibro is not recommended for use in the following conditions:
Anfiber is administered by subcutaneous injection. The drug is administered in order of priority first to the left and then to the right lateral or inferior abdominal wall.
During the injection period, the patient should be in a prone position. The needle is injected vertically and the entire length, before the introduction of the skin should be rubbed with alcohol solution, clamp the skin in the form of a crease between the fingers. Do not administer the drug intramuscularly!
Patients with a moderate risk of developing thrombotic pathologies and thromboembolism during surgical interventions of the general surgical type should be administered 20-40 mg of the drug once every 24 hours. The first administration is carried out 2 hours before the surgery.
Patients with high risks of developing thrombotic disease and thromboembolism in orthopedic operative interventions - 40 mg of the drug are administered at 24 hours.
The first dose of medication should be administered 12 hours before surgery.
The course of treatment lasts from 7 to 10 days.
Patients are administered 1.5 mg of the drug per kilogram once every 24 hours or 1 mg per kilogram every 12 hours. Patients with thromboembolic disorders should be administered 1 mg per kilogram every 12 hours. The course of treatment lasts 10 days.
During preventive treatment during the formation of thrombi during the extracorporeal circulation system in hemodialysis patients should be administered 1 mg per 1 kg of body weight.
If there is an increased risk of the disease, the dosage should be reduced to 0.5 mg per kilogram of body weight. In hemodialysis, the drug is injected into the arterial site of the shunt at the very beginning of the procedure.
Among the side effects, the following phenomena occur:
How to inject a shot subcutaneously:
Other important recommendations for therapy with the drug:
Reviews of patients and doctors who use Anfibro in practice.
The drug Anfiber is an effective agent in the treatment of thrombotic and thromboembolic diseases. I quite often prescribe it with severe forms of thrombosis and thromboembolism.
It's not once in my practice this tool did not hurt my patients, most likely on the contrary after a full course of treatment they have normalized their condition, they have had pain and inflammation.
Anfiber is an effective remedy that helps cure various serious thrombotic and thromboembolic pathologies. During application, it quickly eliminates the focus of inflammation and normalizes the general condition.
Many of my patients who used this agent to treat thrombosis and thromboembolism noted that pain and inflammation were gone after the second injection.
For the treatment of deep vein thrombosis and varicose veins, the doctor prescribed Anfiber. I was given a subcutaneous route for 10 days.
I'd like to note that immediately after the second injection I noticed tangible improvements - the pain, inflammation, heaviness were gone. I went through a full course of treatment and feel just fine!
Nadezhda, 59 years old
Varicose veins and thrombosis appeared relatively recently, but immediately noticed a palpable discomfort - pain, heaviness, swelling. After the examination, the doctor appointed me to Anfibro. Yes, really good drug. Now my health has improved a lot!
Svetlana, 43 years old
Price preparation Anfiber depends on the amount of active substance and the number of ampoules in the package:
Analogs of the preparation:
Low molecular weight heparins are not interchangeable! It's worth remembering.
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