Effectiveness Diosmina: evidence base, testimonials, instructions

Diosmin belongs to the category of medicines containing in their composition bioflavonoids of natural origin - diosmin and hesperidin.

This drug is a widely claimed angioprotector of plant origin, which is used to effectively treat any stage of varicose veins.


  • Pharmacological action
  • Pharmacokinetics
  • drug Indications
  • When medication does not take
  • mechanism of action
  • Instructions for use
  • Overdose and the additional guidance
    • Cautions
  • Complex opinion
  • cost
  • funds available analogues

Pharmacological action

Diosmin is recommended for allstage of venous insufficiency. Its active component is the same substance - micronized diosmin, which can accelerate the lymph flow several times.

Due to its unique composition, the drug perfectly strengthens the walls of blood vessels and increases their overall tone, prevents the onset of inflammatory processes.

The drug has a positive effect in the case of venous blood stagnation in the

lower extremities, and also helps normalize the blood flow in the capillaries.

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Pharmacokinetics of the drug

This medication is one of the drugs with high absorption values. After ingestion, the drug is rapidly absorbed in the gastrointestinal tract after just one hour.

Maximum level of Diosmin in the blood is reached approximately 5 hours after taking the drug.

Active substances present in the drug are completely eliminated from the body after 11-12 hours. The main components are derived naturally - during urination or defecation. Some of the active substances( 2.5%) are excreted from the body with bile.

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Indications for use

The drug refers to preparations of a rather wide spectrum of action. Its use is recommended in such cases:

  • varicose veins of the lower extremities;
  • presence of lymphatic insufficiency of a chronic character in the area of ​​the lower extremities;
  • microcirculation disorders;
  • hemorrhoids in the stage of exacerbation - in this case Diosmin promotes effective strengthening of the walls of blood vessels and reduces the manifestations of the inflammatory process.

When the drug does not take

The drug has a number of contraindications that must be taken into account before proceeding with the treatment Diosmin:

  1. The main active ingredient in the medication is micronized diosmin, which can cause in the human body the allergic reactions of .Allergy is a serious contraindication to the use of the drug.
  2. The drug is prohibited from use in during pregnancy or breastfeeding .
  3. Not intended as for the treatment of children and adolescents under the age of 18 years .
The drug should be discontinued immediately if there is an individual intolerance to one of the active components of the drug.

Mechanism of action

A medicinal preparation is taken internally. After taking an hour later micronized diosmin is actively absorbed by the organs of the gastrointestinal tract.

Due to the intensive absorption of the drug, its maximum concentration in the blood is reached at a rapid pace, which, accordingly, leads to the appearance of the expected therapeutic effect.

Instruction for use

The drug is in the form of tablets. Each tablet contains 500 mg of active substance - diosmin. The dosage of the drug taken depends on the form of the disease and its stage:

  1. In case of chronic venous insufficiency, the standard dosage of is used - 500 mg twice daily before meal. It is recommended to apply the drug in the morning and evening. The course of treatment - at least 2-3 months.
  2. In the treatment of hemorrhoids in acute form should take 6 tablets per day, dividing the reception twice. This means that you need to take 3 tablets in the morning and in the evening. This dosage of the drug is used during the first week of treatment. Further within 3 days should take 4 tablets a day. The duration and further dosage of the drug should be checked with your healthcare professional.

Overdose and supplemental indications

Diosmin can cause certain side effects:

  • intense or paroxysmal headache;
  • allergic reactions or rashes on the skin;
  • various disorders in the normal functioning of the digestive system.
In case of any side effects, you should take a break in the course of treatment. If re-emergence of adverse reactions is recommended, replace Diosmin with another drug.

Special instructions

In the treatment of acute hemorrhoids, special attention should be paid to the fact that the use of the medication should not last more than 10 days. The course of treatment should be combined with the intake of other specific proctological drugs.

When treating varicose veins, Diosmine should be combined with other preventative measures.

These measures include sufficient physical activity, frequent outdoor activities and walking, proper nutrition and careful control of body weight, wearing special compression lingerie to normalize the blood flow in the lower limbs.

No information and no overdose of the drug.

Do not take Diosmin during pregnancy and lactation. If necessary, the course of treatment with the drug should temporarily stop breastfeeding. Also, the remedy is not assigned to children and adolescents under the age of 18 years.

As a result of clinical studies, it has been established that taking the drug does not affect the concentration of attention and does not affect the ability to manage complex mechanized systems or vehicles.

When this drug is used simultaneously with epinephrine or serotonin, their vasoconstrictive effect is enhanced. Interactions with other drugs have not been identified at this time.

Comprehensive opinion of

Reviews of Diosmine patients and doctors.

Diosmin has a positive effect at any stage of varicose veins.

But do not think that the drug is a real "panacea" - be sure to combine the device with other specific medicines, as well as local agents.

Vera Petrovna, St. Petersburg

Many patients suffering from hemorrhoids, I recommend taking a course of treatment with Diosmin. This drug has a very positive effect, especially in the presence of hemorrhoids in the acute stage.

But the treatment can not be continued for more than 7-10 days, after which other drugs should be taken to fix the therapeutic effect.

Tatiana Ivanovna, Nizhny Novgorod

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Several years I suffer from varicose veins. Already tried everything - ointments, creams, special corrective knee socks. The effect was short-term. The phlebologist advised to combine all these means with the reception of Diosmin - the effect pleased me pleasantly!

Already 3 weeks after the beginning of the course of treatment, I felt a noticeable relief, the manifestations of the disease began to decrease intensively.

Victoria, Volgograd

I spend practically the whole day on my feet - I can sit down very seldom. Fatigue, heaviness in the legs are my main problems. Recently noticed the appearance of edema, because of which I can not even wear my usual shoes.

Friends advised Diosmin. I read reviews on the Internet and decided to try. A few weeks later, I noticed that the puffiness has decreased much, the heaviness in the legs no longer causes such anxiety. I will continue to take it!

Larissa, Kazan

Cost of product

The drug is available in the form of tablets, each containing 500 mg of active substance. The package may contain 30 or 60 tablets packed in a contour mesh package.

Average price Diosmina, depending on the number of tablets in the package, varies within 430-750 rubles .

The drug should be stored in a dark and dry place at room temperature, not exceeding a mark of 25 degrees Celsius.

Available analogs

This medication has a number of analogues - preparations with similar active ingredients in the formulation.

To Diosmina analogs, one can include Diovenor, Flebodia, Wacoset, Venarus, Detralex, Fleboph.

The main active substance in these medicines is also diosmin, which allows using them for effective treatment of varicose veins.

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  • Mar 03, 2018
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