Troxsevenol is a drug for the treatment of chronic venous insufficiency. This is a combined agent for topical application.
Presented as a homogeneous transparent yellow gel with light opalescence.
Medication refers to a capillary-stabilizing group of agents.
The drug is a derivative of routine and has P-vitamin activity. Reduces the likelihood of fragility and permeability of the capillaries.
Removes edemas and is involved in the oxidation-reduction processes of the body. The drug itself is non-toxic, has a wide range of therapeutic effects. With local applic
Active substances of the drug prevent the appearance of the vasodilating effect of histamine, bradykinin and acetylcholine. According to the pharmacological group, medicament refers to angioprotectors.
The medication has a gel base, which ensures complete solubility of the active components and their penetration into the inflamed areas. Contained in the drug indomethacin combines with plasma proteins more than 90% and passes in the liver biotransformation. Indomethacin is excreted from the body together by feces and urine. Capable of penetrating into breast milk.
The gel is able to be absorbed quickly from the skin surface if the application is external. If the reception is internal, then the remedy is well excreted from the gastrointestinal tract. The therapeutic concentration of the drug in the blood plasma is maintained for eight hours.
The drug is available in the form of a gel in aluminum tubes and cans. The capacity of any kind of packaging is 40 g. There are five forms of the drug:
100 g of gel is included in 2 g of active substance troxerutin, 3 g indomethacin and auxiliary components in such quantity:
Dosage form of the drug is presented as a gel from yellow to yellow-green color.
The active substance of the drug begins to exert an anti-inflammatory effect and relieves puffiness.
When applying the gel to the affected area, the inflammation decreases and platelets stick to the surface of the vascular wall.
The active substance of the drug blocks hyaluronidase and stabilizes the level of hyaluronic acid concentration. Flavonoid, which is contained in the drug, strengthens the density of the vascular wall and prevents the exudation of the liquid part of the plasma.
The indomethacin contained in the preparation stops the synthesis of prostaglandins by reverse blockade of the cyclohexane enzyme. Also, the active substances are able to prevent the aggregation of platelets.
Troquenoven is used in the presence of the following diseases:
Trocevenol in capsules is taken with food, the capsule must be swallowed whole. Multiplicity of admission is three times a day. As a supportive therapy and for the prevention of the drug is prescribed one capsule twice a day.
The daily dose of the drug is 70-90 mg. On average, the duration of treatment is about three to four weeks. The appointment of a longer course is carried out exclusively on an individual basis.
Troxsevenol in the form of a gel is applied externally. On the damaged area is applied a column of gel 4 cm high and gradually rubbed into the skin. The daily dose of gel is 20 cm. The course of treatment with the use of gel should not exceed more than ten days. Multiplicity of gel usage is 3-4 times a day.
Overdose occurs when the daily dose is exceeded and with a long course of treatment. As a result, severe headache, hepatotoxicity and hemorrhage can occur.
Internal medicine may cause burning in the mouth, nausea, vomiting and copious salivation. In this case, you need to wash the mouth and stomach. In case of serious damage to these organs, preventive treatment is prescribed.
The drug on the mucous membranes and not tightened wounds causes irritation, which is manifested by burning, hyperemia, lacrimation and pain.
The gel is washed off from the affected area with a large amount of water or with an isotonic sodium chloride solution. The gel should be washed off until it completely disappears or the severity of the characteristic symptoms decreases.
Side effects of the drug include the occurrence of an allergic reaction( skin rash) and erosive lesions of the gastrointestinal tract. It is also possible manifestations of a symptom of hypersensitivity( bronchial asthma, anaphylaxis).
The drug is not recommended for use to people who have not reached the age of fourteen. This is due to the lack of clinical experience. Doctors do not recommend drinking alcohol during the course of treatment, as this increases the likelihood of side effects.
Administration of the drug is prohibited during the first trimester of pregnancy. If it is urgently needed, it can be used only in the second and third trimester, but solely for the doctor's prescription.
Troxequenol can not be used concurrently with other steroidal anti-inflammatory drugs. Also, concurrent use with corticosteroids is not recommended, because of the possibility of ulcerogenic action.
When combined with the above preparations, the effect of ascorbic acid on the structure of the vascular wall and its permeability is enhanced.
Reviews of doctors who use Troxsevenol in their medical practice.
Very effective drug, treats even chronic and chronic hemorrhoids. In my practice, patients rarely showed any side effects. If you follow the recommendations of doctors, then there will be no problems.
Semyon Nikolaevich, doctor of neurosurgeon
Very good at removing symptoms that occur with varicose veins of lower extremities. If the course of treatment is not lengthy, then there will be no side effects.
With full course treatment, the probability of further manifestation of venous insufficiency is minimal.
Antonina Georgievna, doctor of neurosurgeon
I have been suffering from varicose veins for 20 years, both my shins are covered with vascular asterisks, and veins very often swell. Initially, I was just recommended to give up heels and just wear golf shoes.
I began to find out myself what I could do, and I learned about the Troxsevenol gel. I used the drug three times a day. The result surprised me pleasantly. Of course, I was not able to completely cure varicose veins, but my swelling disappeared and the blood vessels no longer tore.
Heard that Troxsevenol helps cure hemorrhoids. This unpleasant illness has appeared at me after sorts. A lot of things I tried but, alas. ...Unfortunately, this drug also could not please me.
From the practical application of many patients, it can be seen that the drug can have a positive effect. In most cases, he copes with the ailments of patients. The disadvantage of the drug is the manifestation of side effects that occur in rare cases( overdose, sensitivity to the drug).
Troxsevenol is available in the form of a gel( tubes of 40 g) and in the form of capsules( 30-60 mg), the average price for capsules is 190 rubles, the cost of the gel is 100 rubles.
The medicine should be stored in a dark dry place at an air temperature of not more than 25 degrees. Shelf life of the drug is two years. Do not freeze the drug. It is released without presenting a prescription.
Troqueneolone has the following analogues:
Analogues of Russian production:
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