Troxerutin refers to medicines of a group of angioprotectants and microcirculation correctors.
The substance of troxerutin is a derivative of routine, related to the semi-synthetic type.
In the normal state, it is a yellow powdery powder that dissolves easily in water, propylene glycol, glycerin. Virtually unaffected by dissolution in ether, chloroform, cold ethanol, benzene.
Troxerutin differs pronounced activity venotonicheskogo, membrane stabilizing, an
P-vitamin activity of the drug promotes activation of oxidation-reduction processes, stabilizes the level of hyaluronic acid of cell membranes, reducing the overall background of their permeability.
The activity of the drug promotes the normalization of the permeability of the capillary walls, increasing the overall tone.
Also, the action of troxerutin is aimed at increasing the level of vascular wall density, reducing the exudation of the liquid segment of plasma and diapedesis of blood cells.
There is a decrease in exudative inflammatory processes in the area of the vascular walls, limiting the adhesion of the wall to the surface of platelets. The drug is applicable both at the beginning of treatment and at the late stages of the course of the disease.
It is possible for to use troxerutin as a component of the complex therapy of .
For the administration of the drug inside, the substance is absorbed from the gastrointestinal tract.
The maximum concentration level of the substance in the plasma is fixed approximately two hours after ingestion.
The substance is metabolized in the liver. It is excreted from the body partially in an unchanged state, along with bile and urine.
The drug is prescribed if the patient has such types of diseases:
When not allowed to use preparation:
Advantageously, works on venous vessels, strengthening the venous walls, reducing the level of their permeability.
During the application of the drug, the level of elasticity and tone of the venous valves increases. Troxerutin promotes the inhibition of inflammatory processes and the development of thrombotic formations in the veins.
It can also be prescribed to patients with painful symptoms that are traumatic ( as an example, sprains, dislocations, contusions, tonic muscle cramps).
Applicable in as a component of the comprehensive hemorrhoid treatment i. The drug is applied orally( capsules) and externally( gel, ointment).Instructions for the use of capsules, gels and ointments of Troxerutin are set out below, among the highlights, should be remembered:
The capsule is taken as a whole, without chewing and / or pre-grinding. Take the capsule with a moderate amount of liquid. It is recommended to use capsules during food intake.
The duration of therapy is determined by the physician. Most often, adult patients are assigned one capsule two to three times a day until the symptoms disappear.
The drug is then used as a prophylactic agent with supporting functions( one capsule once a day).The total duration of therapy can vary from 5 to 7 weeks.
It is recommended to apply the substance on the skin in the area of affected areas with a thin even layer.
With gentle massage movements, the gel is rubbed into the skin. The drug is prohibited from applying to the inflamed areas of the skin and mucous membranes. Do not get the gel into the eyes. After applying the gel, you should wash your hands.
The duration of therapy is determined by the attending physician. Adult patients of are prescribed rubbing with gel two to three times per day. Combined therapy is also acceptable.
Dangerous acute thrombophlebitis of superficial veins can result in death. How to avoid this unpleasant disease?
Internally during meals, the drug is taken at 0.3-0.9 g during active therapy. As maintenance therapy, taking the drug is internally reduced to 0.3 g within 24 hours.
For external( local) application of the gel, 2% of the substance is used, evenly applied in a thin layer to the area with severe symptoms.
At the moment there is no evidence of an overdose of the drug.
In case the preparation in the form of capsules was taken at a significantly higher dosage, or an accidental ingestion of the drug in the form of a gel, it is recommended to rinse the stomach and then take enterosorbents.
Possible manifestation of such symptoms, as:
Similar processes after taking the substance may manifest as symptoms:
As a result of taking the drug, no negative mental and / or motor reactions occur. The preparation does not interfere with driving and / or mechanical work.
In case the drug is used in the treatment of superficial thrombophlebitis or deep vein thrombosis, combining the use of agents with anti-inflammatory and antithrombotic properties is not excluded.
With combined therapy, Troxerutin enhances the action of ascorbic acid on the level of permeability and the integrity of the structure of the vessel walls.
Troxerutin in capsule form for internal use is not recommended for use in the first trimester of pregnancy.
In the future, the drug is prescribed by the doctor, taking into account the excess of the expected benefit from therapy in comparison with the possible risk to the fetus.
A substance in the form of a gel can be used during pregnancy. Also the use of the drug in the form of a gel does not require interrupting the treatment of for the lactation period, since the substance has a low level of systemic absorption.
At the same time during the breastfeeding , the use of capsules is undesirable.
The drug is widely used by modern consumers to relieve swelling of the lower extremities. The most positive reviews of patients about Troxerutin gel, a little worse about Troxerutin in capsules
Such statements are widely supported not only because of the effectiveness of the drug, but also at a very reasonable cost.
The price for Troxerutin varies depending on the form of release and the size of the package.
How to replace the drug
There is a large number of analogues of Troxerutin. Let's dwell on the main ones.
is used by as a preventive and symptomatic therapy for chronic venous insufficiency. In the process of taking the drug, there is a reduction in the level of permeability of the capillary walls, angioprotective effect.
Antistax is based on the extract of red grape leaves with the addition of active flavonoids( quercetin-glucuronide, isokvertsetin).
Antistax is available in capsules of 20 pcs.in a cardboard package of 180 mg.
The cost of the drug varies from 540 to 1300 rubles.
The chemical structure of the hydrosmin active substance belongs to the group of flavonoids. The substance affects the level of reduction in permeability of capillary walls caused by the use of substances such as histamine, bradykinin and others.
Stabilizes and improves the properties of erythrocytes of a hemorheological nature. The preparation reduces the level of fragility of capillaries , which was caused by improper diet, reduces the level of viscosity of the blood.
Venosil improves the clinical symptoms of venous insufficiency of the peripheral type( eg, swelling, pain impulses, sensation of gravity during movement and / or breathing).
The drug is prescribed to patients for a short-term relief of the symptoms of the disease and is taken no more than three months. Produced in the form of capsules in blisters for 6-9 pieces in a cardboard box.
The cost of the drug is from 959 rubles.
The action of the drug Venoruton has a venotonic and angioprotective effect.
The drug is available in the form of capsules for internal administration and as a gel for external use. The substance helps to strengthen the vascular walls, normalizes the level of their permeability.
The use of prevents intercellular cracks and a sharp increase in the level of hydroconductivity.
The cost of the drug in capsules for internal reception is the amount from 590 to 700 rubles .Venoruton gel can be purchased 270-330 rubles.
The preparation is used by for the symptomatic treatment of venous insufficiency, superficial thrombophlebitis, pre-varicose and varicose symptoms, phlebitis and as part of a comprehensive hemorrhoids treatment.
Eliminates the symptoms of - swelling, pain impulses, muscle cramps( convulsive heaviness in the calf muscles).The drug is available in the form of 2% gel for 40 / 100g in aluminum tubes and carton.
The cost of the gel varies from 140 to 470 rubles.
is prescribed to patients as part of a set of pathological measures, accompanied by an increased level of vascular wall permeability.
The substance can also be used as a prophylactic for colds, as it helps to reduce the symptoms - headaches, painful spasms.
The drug is vitamin and is available in the form of tablets of 50 pieces per pack.
The cost of askorutin is from 25 to 35 rubles.
The combined preparation has anti-inflammatory, anti-edematous, aneliziruyuschim action and is intended for external use. It helps to reduce swelling, pain syndromes, reduce the level of permeability and fragility of capillaries.
Has a strengthening effect, stabilizing the tone of the vascular walls.
Promotes improvement of microcirculation processes. The preparation is made in the form of a gel for external use of 45 g in an aluminum tube and carton.
Approximate cost of the drug - 180 rubles.
The preparation is manufactured in the form of capsules for internal use.
Has features such as: reduction of pain syndrome, increased level of stability of capillary walls, reduced permeability of vessel walls, restoration and stabilization of microcirculation and venous blood flow.
Combined drug is prescribed for patients with venous circulation disorders. The estimated cost of the drug is 440 rubles.
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