Nitroglycerin - instructions for use. The action of nitroglycerin in heart attacks, pain, dyspnea, pressure

This article will be information on all aspects of the use of the drug Nitroglycerin. We will talk about the combination of a drug with alcoholic substances and the effect of the drug on the patient's body, we will indicate analogues of this drug.

First of all, it should be noted that "Nitroglycerin" is a tool used in the cardiological direction and has a synthetic origin. This drug belongs to a group of drugs that are called "Organic Nitrates."

"Nitroglycerin" instruction for use

"Nitroglycerin" instruction for use

• Nitroglycerin has the properties of the vasodilator, that is, it expands the spasmodized vessels. At the same time, its action, at least, is directed to the venous system, the vessels of the heart and brain. The action of the medication is observed already after 2 minutes after its application, with the maximum effect being noted after the expiration of nearly half an hour from the time of taking the remedy. The action of nitroglycerin lasts for 1 hour on average
• When receiving the remedy under the tongue at the time of the angina attack, it can be stopped by taking the preparation already, and for 1.5-2 minutes. In this case, the action of the agent is observed on from half an hour to 1 hour after the application of nitroglycerin
• The action of the device is aimed at relaxing the smooth muscles of the body, for this reason, in addition to the main effect, the product relaxes the muscles of the biliary tract, gastrointestinal tract and other internal organs.

.nitroglycerin under a group of agents that improve myocardial metabolism and its blood supply.

Nitroglycerin indications for use

Nitroglycerin indications for use

The main application, as we already mentioned earlier,

"Nitroglycerin" found in cardiology, therefore the following pathologies serve as indications for its use:

• Spasm of coronary vessels( blood vessels, blood supply)
•Symptoms associated with the manifestation of angina pectoris
• Ischemic heart disease and pre-infarction and infarction on the background of the hypertensive crisis
• Heart failure is differentth degree
• Spastic condition of the vessels of the eyeball
• With a planned surgical intervention in neurosurgery with nitroglycerin, artificially reduce the blood pressure of
. • When narrowing( of dyskinesia ) of certain parts of the digestive tract

, the treating doctor may indicate in the recommendations any of the forms of release of this drug. To use you can choose the one that suits you best.

Form of production of nitroglycerin and application: tablets, spray, ointment, solution, in ampoules intravenously

Nitroglycerin dosage form and application: tablets, spray, ointment, solution, in ampoules intravenously

"Nitroglycerin" has a fairly extensive list of manufactured forms, namely:

• Sublingual capsules( applied under the tongue) with a substance content of 0.5 mg
• Tableted form, which is applied subkumally( on the cheek) with a substance content of 0.5 mg
• Solution for intravenous injection( ampoules for the injection)
• Aerosol orSpray for irrigation of the oral mucosa( under the tongue)
• Tablets coated with a coating that have a longer action with a substance content of 5.2 mg
• In the form of a patch, the drug is applied transdermally

"Nitroglycerin": dosages of

"Nitroglycerin": dosages of

In this section, we will discuss the methods of application and dosage of the above mentioned forms of the preparation.

The use of this medication is recommended only after consultation with the cardiologist and with his appointment.
• Capsules for sublingual application are recommended to be placed under the tongue and, without swallowing, hold under the tongue until the is completely dissolved. capsules are assigned this form of the pain in the region of the heart to adults in a dose of 0.5 to 1 mg per application. A day can not be used more than 6 capsules, with a single dose should not exceed 2 capsules
• Solution for intravenous administration is used as follows: in dilution in a 5% glucose solution or in 0.9% sodium chloride solution with a concentration of 100 or 50 μg per 1 ml. Enter the solution drip with a gradual increase in dose every 5 minutes until the moment when the effect of the drug is noted or the speed of administration of the drug is increased to 0.02 mg per minute. If this insertion rate does not have the effect of , then further it increases by 0.01 mg per 1 minute
• Application of the patch( or transdermal application of the drug) is carried out by sticking on the skin for up to 14 hours, then remove the patch and take a breakfor the next 12 hours to prevent the development of immunity.
• Tablet or capsule form is taken orally without chewing or breaking the integrity of the tablet( fracture).Such forms of release are accepted up to 4 times a day before eating for half an hour. Since the penetration of the substance into the body is difficult in this case, the single dose of the drug can reach 19.5 mg of
. • Use of the drug on the cheek or sub-bokalno is carried out by placing the tablet on the mucosa of the mouth in the cheek area until it dissolves completely. The dosage is 2 mg not more than 3 times a day

The action of nitroglycerin against pain, with heart attacks

Action of nitroglycerin against pain, with heart attacks

Before we tell you the mechanism of pain relief with nitroglycerin, let's understand for the reason of this sensationbehind the sternum.

• Angina pectoris or, as it is also called in the people "angina pectoris", can be characterized by acute or squeezing pain in the chest area. The reason for this is an acute disruption of the blood supply to the heart muscle and its oxygen starvation, and accordingly the ability to adequately perform its contractile function for the distribution of blood
• . In this condition, the coronary vessels are narrowed and the only way to resolve this situation is to widen the lumen of the vessel to ensure free flow of blood
• In order to widen the vessels from them it is necessary to remove the rescued state. And , as we already wrote, "Nitroglycerin" has the properties of excellent vasodilator .It is for this reason that it quickly and effectively relieves the pain

How to apply nitroglycerin in dyspnoea, pressure?

How to apply nitroglycerin for wheezing, pressure?

We will begin to understand this issue in order of priority.
Article on Hypertension and increased blood pressure you can also find on our website and read about the disease in more detail.

• If in brief understands this issue, then the cause of pressure increase is also is a spasm of smooth muscles and, accordingly, the vessels of our body
• To remove this spasm from the vascular bed can also be through the use of nitroglycerin, and removing the spasm, we ease the burden on the heartand reduce total blood pressure.
• . Shortness of breath is also a symptom of an attack of angina or heart failure. If there is a violation of the blood supply to the heart, his work is disrupted in the same way, while lung function also affects the exchange of oxygen and carbon dioxide.
• A "vicious circle" to the heart of the non- is missing of oxygen and it suffers, and oxygen can not adequately enter the bloodstreamchannel due to disruption of the heart

Thus, by removing the spasm and providing an adequate blood supply to the cardiac muscle , we can normalize and work light .

"Nitroglycerin" infarction

"Nitroglycerin" infarction

• It should be noted that the frequent cause of the infarction is precisely a sharp narrowing of the coronary lumen of the
• It is for this reason that "Nitroglycerin" can become a "life-circle" in myocardial infarction
• . But this is only in thatif the cause is precisely the spasm of the vascular bed

Contraindications to the use of "nitroglycerin"

Contraindications to the use of "nitroglycerin"

The use of this tool is available•

• Collapse state
• Shock state
• Reduced blood pressure
• Acute myocardial infarction and marked decrease in blood pressure
• Cardiopathology associated with hypertrophy and obstruction
• Inflammation of the pericardium
• Tamponade( rupture) of the heart
• Pulmonary edema due to
poisoning • High intracranial pressure
• closed-angle glaucoma
• Patient intolerancewaste

"Nitroglycerin" side effect

"Nitroglycerin" side effect of

The following conditions are related to the side effects of the drug:

• Headaches
• Dizziness
• Heart palpitations
• Redness of skin
• Feeling of heat
• Blood pressure lowering
• Wollaptoid condition
• Bluishness of the skin
• Skin rashes and other skin manifestations

What happens if I overdose nitroglycerin?

The following conditions may occur if the drug is used excessively and exceeds the recommended dose:

• Headache, dizziness
• Pressure in the head
• Excessive weakness and fatigue
• Fainting and collapsoid states
• Increased body temperature
• Boostintracranial pressure

If symptoms of an overdose occur, the patient should be moved to a horizontal position with raised legs( legs should lie abovehead level).To remove the effect of the drug intravenously administered antagonists alfaadrenoblokatorov ( phenylephrine ).

What is the lethal dose of nitroglycerin?

What is the lethal dose of nitroglycerin?

• It should be well remembered that the use of nitroglycerin is indicated only for the doctor's prescription and strictly in the prescribed dosages of
• . There is no exact answer to the question of the lethal dose of this drug, as for each patient this dose of is variable .The fact of an overdose and death depends on the individual characteristics of the organism of each of the patients prescribed the preparation of this drug
• . Cases of deaths are described even when 1 therapeutic dose is administered, but before the prescribed interval

"Nitroglycerin" and alcohol

"Nitroglycerin" and alcohol

• Everyone knows that taking any medication in combination with alcohol is strictly contraindicated, and especially for cardiac medicines
• Alcohol in addition to its toxic( poisoning) effect also has the vasodilating effect of
• . In combination with alcohol, nitroglycerin can exert excessive vasodilation of anda sharp drop in blood pressure. provoking thereby deep collapse and possible cardiac arrest

«Nitroglycerin": analogues

• Deponit 10
• Nitradisk
• Nitro
• Nit-ret
• Nitro-Dur
• Nitrodzhekt
• Nitromint
• Nitross
• Nitrospray
• Sustonite
• Sustack mite
• Trinitrolong

Nitroglycerin: feedback from

It should be noted that we did not find negative reviews about this medication."Nitroglycerin" is an improvised emergency aid for angina attacks and to date has not found any more accessible and easy-to-use substitutes.

Video: Why can not nitroglycerin save and kill?

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