Validol is an anti-anginal remedy whose indications for use are mainly related to the field of cardiology. The drug is effective in neurogenic, and not organic spasms of blood vessels, and therefore is used as a sedative. Validol is safe, does not accumulate in the body, is non-toxic and is affordable.
- Structure and Composition
- Mechanism of action Indications
- How to take
- Capsules
- Tablets
- Drops
- Contraindications
- Side effects
- Overdose
- With alcohol
- Children
- during pregnancy
- Analogs
- Barboval
- Valocordin( Valoserdin)
- Glycine
- Corvalol
- Cardiolin
- Persen
- Pumpan
- Tricardin
Composition and Form of Release
The main active ingredient of Validol is the solution of levomentol in mentlizovalerate. Produced in the form of sublingual capsules, tablets and drops. In the composition of tablets, in addition to the solution of levomentol is glucose.
to contents ^Mechanism of action
When entering the oral mucosa, menthol irritates the nerve endings. As a result, the reaction of ejection into the blood of biologically active substances is triggered: kinins and histamine, endorphins and enkephalins.
Kinins and histamine dilate the blood vessels than relieve cardiac and headaches. Endorphins stabilize blood pressure and respiratory rate, and enkephalins have a depressing effect on the central nervous system, in addition, these morphine-like substances have an analgesic and soothing effect.
Indications
- Cardioneurosis;
- angina attacks( only in combination with nitroglycerin);
- neuroses( neurasthenia, hysterics);
- strong emotional stress, stress;
- seizure attacks;
- toxemia of pregnant women in the first trimester;
- headaches;
- heart tachycardia;
- convulsive movements of the limbs;
- increased pressure.
How to take
to the table of contents ^Capsules
The preparation is placed under the tongue and is waiting for its complete resorption. Consider a single dose of 1 capsule( 50 or 100 milligrams), the maximum dose per day - 600 milligrams. Validol begins to act after 5 minutes.
to table of contents ^Tablets
The tablet is placed under the tongue and held there until it is completely resorbed. The dose for one dose is 1 tablet( 60 milligrams), the maximum daily dose is 300 milligrams. The drug will act after 3-5 minutes.
Tablets Validol can also be used for inhalations from cough. To do this, they are dissolved in boiling water and allow the patient to breathe a steam.
to contents ^Drops
3-6 drops of liquid Validol are applied to a piece of sugar and kept under the tongue until complete resorption.
to table of contents ^Contraindications
- Allergy to menthol;
- age under 2 years;
- low pressure;
- acute myocardial infarction.
Side effects
- Lachrymation;
- sneezing;
- dizziness;
- nausea;
- Quincke edema;
- urticaria;
- skin rash.
Overdose
In case of drug overdose:
- sharp decrease in blood pressure;
- nausea, resulting in vomiting;
- severe headache;
- overexcitation;
- suppression of the functionality of the central nervous system;
- oppression of all reflexes, including respiratory( lethal outcome).
Validol is excreted in the urine for 6-8 hours. If there is only mild nausea, then no special measures need not be taken. But if vomiting increases, and the condition is close to fainting, you need to call an ambulance, and before she arrives put the patient on its side and warm it.
to the table of contents ^With alcohol
Alcohol reduces or distorts the action of any medicine, but its combination with vasodilators is especially dangerous. Alcohol is quickly absorbed into the blood, as a result, the vessels expand, the person relaxes, feels calmer, but this action of alcohol does not last long. Within 2 hours the vessels narrow, the heart rate increases, there is a spasm and pain in the heart.
If at this moment to drink Validol, then it will not bring relief, since the remnants of alcohol completely neutralize the effect of the drug. If the patient has some kind of heart disease, then the multidirectional actions of alcohol and drugs can lead to his exacerbation.
The combination of alcohol and Validol can lower blood pressure, a person's reaction will be slowed down, which is especially dangerous when driving vehicles.
Children
Validol should not be given to children under 2 years of age, since the action of menthol on the mucosa can cause reflex stopping of breathing. The effect of the drug on children from 2 to 12 years has not been studied, so you can use the medicine only as prescribed by the doctor and in strict dosage. For older children, Validol may be used in the form of inhalations to cough.
to the table of contents ^When pregnant
Doctors agree that the use of Validol is possible in the early stages of pregnancy, but under the supervision of the doctor and in a small dosage, since the drug can significantly lower blood pressure. The maximum daily dose for a pregnant woman is 60 milligrams. With an acceptable dosage, the drug can relieve debilitating attacks of nausea and heartburn. Validol at any time of pregnancy can be used in the form of inhalations.
to contents ^Analogs
By active substance:
- Kormenthal;
- Corvalence;
- Gulidol.
By treatment:
to table of contents ^Barbovan
Active ingredients: menthol solution in isovalerate, phenobarbital, ethyl ester of acid alpha-bromizovaleric. Available in the form of drops and capsules.
It is used for neuroses, angina pectoris, hysterical conditions, arterial hypertension.
Drops are taken with water orally or on a piece of sugar under the tongue. Usually, 10-15 drops are prescribed per 1 dose three times a day, half an hour before meals. Capsules are taken 3 times a day for 1-2 pieces, the course of treatment is 14 days.
Side effects: hypotension, urticaria, decreased attention, nausea. With long-term use, the drug becomes addictive.
Valocordin( Valoserdin)
Active ingredients: phenobarbital, ethyl bromizovalerianate. Available in the form of drops.
It is used for tachycardia, cardialgia, insomnia, neuroses, a sense of anxiety, a state of arousal and hysteria.
The usual dosage for adults is 15-20 drops three times a day, with insomnia one can take 30 drops once.
Side effects: drowsiness, occasionally light dizziness.
Glycine
The active ingredient is glycine. Produced in the form of tablets.
It is used for stress, insomnia, neuroses, low mental performance, high excitability.
Tablets are applied sublingually or buccally( the tablet is laid between the gum and the upper lip and kept until completely dissolved) 1-2 tablets 2-3 times daily, before meals or after( indicated by the doctor).The course of treatment is designed for 2-4 weeks, the course can be repeated 4-6 times a year.
Side effects: extremely seldom possible allergic reaction.
Corvalol
Active ingredients: peppermint leaf oil, phenobarbital, ethyl bromizovalerianate. Produced in the form of drops and tablets.
It is used for neuroses, high blood pressure, insomnia, with mild tachycardia and coronary spasm.
Corvalol in drops are taken with water or with a slice of sugar half an hour before meals. Usual dose - 20-30 drops per reception, with a strong tachycardia, a single dose of 50 drops of the drug is possible. With insomnia, 30 drops are dissolved in warm water and taken for half an hour before bedtime.
Corvalol in tablets swallow whole or, if you need a quick effect, apply sublingually( put under the tongue until complete resorption).
Side effects: indigestion, dizziness, headaches, allergic reaction.
Cardiolin
Active ingredients: extracts from the herb of spring spring, juniper fruit, arnica mountain flowers, peppermint leaves. Available in the form of drops.
It is used for heart neuroses.
The drug is prescribed for 20-30 drops for half an hour before meals, 2-3 times a day. The average course of treatment is 20-30 days.
Side effects: individual intolerance.
Persen
Active ingredients: extracts of valerian, lemon balm, peppermint. Produced in the form of tablets.
It is used for neuroses, states of excitation, insomnia, vegetovascular dystonia, stress.
Tablets are taken orally by washing with water. Adults and children after 12 years of age are usually prescribed 1 tablet 2-3 times a day. With insomnia, the recommended dose is 2-3 tablets in the evening, half an hour before bedtime. The maximum daily dose is 12 tablets. The course of treatment is no more than 1.5 months.
Side effects: allergic skin rash, bronchospasm, constipation.
Pumpan
Active ingredients: potassium carbonate, extracts from mountain arnica, hawthorn, May lily of the valley, purple foxglove. Produced in the form of tablets and drops.
It is used for hypertension, arrhythmia, ischemic heart disease, vegetovascular dystonia.
Drops are dissolved in water and drink 10 drops three times a day, tablets are best used sublingually for 1 unit 3 times a day. The course of treatment is designed for 1-3 months.
Side effects: in the first days of taking the drug, there may be a worsening of the condition( this does not require withdrawal of the drug).
Tricardin
Active ingredients: extracts from valerian, motherwort, hawthorn. Available in the form of drops and capsules.
It is used for neurasthenia, sleep disorders, hysteria, migraine, arterial hypertension, vegetovascular dystonia, physical and mental fatigue.
Drops diluted with boiled water, take 2-3 times a day for 20-40 drops, capsules are taken orally. The course of treatment is designed for 1-1,5 months.
Side effects: dizziness, weakness, urticaria, constipation, drowsiness, skin itching, decreased heart rate.