The drug Ciprofloxacin belongs to the group of fluoroquinolones, it also has a rather wide spectrum of antimicrobial action.
Cypropharm completely inhibits the DNA kinase directly inside the microbial cell, and this can cause a violation of duplication or transcription.
In addition, the drug inhibits the replication of RNA microbial agent and DNA.
Possible changes that are caused by the drug may lead to the death of the microorganism due to bactericidal action.
- 1. Composition of
- 2. Indications for use
- 3. Use of
- 4. Use in ophthalmology of
- 5. Contraindications to
- 6. Side effects of
- 7. Dosage of
- 8. Specific guidance from
- 9. Form of release
- 10. Storage conditions
- 11. The price of the drug in Russia and Ukraine
- 12. Analogues
- 13. Feedback
This effect can be manifested with respect to gram( -) and( +) microorganisms, excellent effect on aerobes, and also in lesser activity is able to exerciseits effects in relation to anerobam.
The preparation of Ciprofarm can be active in various bacteria that produce β-lactamase. Bacteria gram( -): H. influenzae, Pseudomonas aerruginosa, E. coli, Salm.spp., Shigella spp., Neisseria meningitidis, Staph.spp., N. Gonorrhoeae, Enterococcus spp., legionella, Campylobacter spp., mycoplasma, mycobacteria and chlamydia.
In the case of topical use, all the effects are strictly limited to tissues, as well as ear tissues or biological fluids of the eye.
Composition
The main active ingredient is ciprofloxacin hydrochloride.
1 ml of the solution contains 3 mg of ciprofloxacin hydrochloride.
Excipients are:
- Benzalkonium chloride,
- Water for injections,
- sorbitol,
- sodium dihydrogen phosphate dihydrate.
Indications for use
Drug Ciprofarm is mainly used for corneal ulcers, superficial infections of the eye or its appendages caused by highly sensitive microorganisms.
Cypropharm is indicated in cases of acute external otitis media, acute otitis media with a strictly established tympanostomy tube, caused by strains of various microorganisms, quite sensitive to it.
Usage
Usage in ophthalmology
The drug Tsiprofarm is used exclusively topically, instilled in a conjunctival sac. Immediately after instillation it is necessary to close the eyelid densely, in order to avoid systemic absorption.
Adult age group
Use of the drug in case of corneal ulcer should be taken:
- 1st day : only 2 drops with a small interval of 15 minutes for only 6 hours, after which 2 drops at intervals of at least 30 minutesfor 18 hours. All this without an interruption of the night.
- 2nd day : only 2 drops with a short interval of 60 minutes.
- 3-14th day : only 2 drops with a short interval of 4 hours. The duration of this therapy is strictly individual.
In the infectious process of the eye: it is recommended to apply 1-2 drops once every 6 hours. The maximum dose should not exceed 1-2 drops once every 2 hours, a night break is required in the first two days. The full course of treatment is no more than 7-14 days.
Children's age group
The drug has been used since birth. With conjunctivitis, 1-2 drops are recommended once every 8 hours for 4 days. Do not touch the conjunctiva with the tip of the vial. With any other pathology, dosage is carried out exactly the same as in adults.
Application in theology
Drug Ciprofarm is usually applied topically, instillation should be carried out directly into the ear canal.
Application to adults
It is recommended to apply 4 drops every 12 hours. When using an ear swab for the first time, usually only 8 drops are prescribed. In the future, the usual dose should be used. The full course of treatment is 5-10 d.
Children's age group
Applies from 12 months. Drip 3 drops every 12 hours. In the case of the first use of an ear swab, only 6 drops should be administered. In the future, a standard dose should be used.
Preliminary it is necessary to conduct a thorough cleansing of the auditory canal. Do not touch the ear canal with the tip of the vial. You can use extremely warm solutions of about 18-22 degrees.
During the instillation period, the patient should lie exactly on the opposite side of the lesion. Immediately after instillation it is necessary to remain for 10 minutes in the supine position.
Contraindications
Ciprofarm is categorically contraindicated in case of hypersensitivity to any of its constituents, especially to quinolones. The drug is not used for fungal and viral etiology of eye disease.
Ophthalmic tool Tsiprofarm is absolutely contraindicated for children not older than one year.
Tsiprofarm is allowed to be administered to pregnant women only when the potential benefit to the mother of the gammon exceeds the potential threat to the fetus.
Information on the possible penetration of the components of the drug Tsiprofarm after topical application in breast milk is not available. That is why it is very important to take special care when using this remedy for lactating women.
Side effects of
In case of application of the ophthalmic preparation of Ciprofarm, side effects may appear.
Organs of vision : possible sensation of foreign body, appearance of white plaque, discomfort, scales or crystallites formation, itching, conjunctival hyperemia.
In rare cases, corneal staining, photophobia, allergic reactions, keratitis, keratopathy, eyelid edema, sharp reduction in visual acuity, lacrimation, corneal infiltration can occur.
Organs of hearing : ringing in the ears, itching in the ear.
In addition, in the case of the use of the drug Ciprofarm may occur dermatitis, nausea, unpleasant taste in the mouth, headache.
If immediately after instillation of drops of Ciprofarm is often noted blurred vision, sick, before driving a vehicle or working with a complex mechanism, you need to wait to restore normal clarity of vision.
Overdose
In case of an overdose of the drug by Cypropharm at the time of instillation in the eye, it is necessary to wash excess water with eyes from the eyes.
In case of an overdose of Ciprofarm during the instillation in the ear, the patient should lie on his side, which corresponds to the ear, and then wait for the excess fluid to flow.
Dosage
Use in the ophthalmology of the drug Tsiprofarm
In the case of superficial bacterial infections of the eyes and its appendages, the standard dose of Ziprofarm should be 1-2 drops only 4 times / day.
It is recommended to instill the drug into the conjunctival sac of the diseased eye. In case of severe infections, the dose of Ciprofarm should be only 1-2 drops every 2 hours in the afternoon. Usually, the duration of treatment should not exceed 7-14 days.
Children older than 1 year in the case of bacterial conjunctivitis, this drug should be used no more than 2 drops 3 times / day for four days.
With the concomitant use of other local ophthalmic drugs, it is important to observe a break of fifteen minutes between instillations.
In order not to contaminate the entire solution, as well as the tip of the vial, during instillation it is necessary to avoid touching it to the eyelids and other surfaces.
Use of Cypropharm in the
The standard dose for adult patients should be no more than 4 drops directly into the auditory meatus only 2 times / day. The duration of therapy should be up to 10 days.
Individual cases allow prolongation of therapy, but in this case it is necessary to determine the sensitivity of possible causative agents of the disease. For young children, the standard dose of the drug should be 3 drops directly into the ear canal only 2 times / day.
In case of concomitant use of other topical medications, it is important to observe an interval of 15 minutes between use.
Special instructions
The combination of Cypropharm with any other local medicines experts recommend to observe the interval of at least 15 minutes .In case of manifestations of allergic reactions, the use of the drug must cease.
In practice, there have been cases of severe systemic reactions when using Cypropharm, which were usually accompanied by vascular collapse, swallow edema, loss of consciousness, hives, or itching.
For particularly severe anaphylactic reactions, epinephrine therapy and resuscitation should be performed immediately.
Tsiprofarm in some cases, the emergence of phototoxicity, which is often accompanied by sunburn, as well as increased sensitivity.
That's why during treatment it is important to avoid insolation. With the development of such a reaction, the drug should be discarded. As a result of prolonged use, resistant forms of bacteria and fungi may appear.
Preservative of this drug benzalkonium chloride can cause gradual irritation of the conjunctiva and discoloration of soft lenses, which is why before using an ophthalmic tool, you need to remove contact lenses, you can dress back 15 minutes after instillation.
In case of inflammation, lens is not recommended. The vehicle can only be operated after full restoration of the fields of vision.
Form
Eye drops. /us.0,3% in the vial 5( 10) ml №1.
1 bottle in a special carton.
Storage conditions
Recommended storage temperature up to 25 degrees Celsius. After opening, you can store up to 28 days.
The price of the drug in Russia and Ukraine
The average cost of the drug Tsiprofarm in Russia is 124 rubles, and in Ukraine no more than 35 hryvnia.
Analogues
Analogues of Ciprofarm are drugs that have a similar effect on the body.
Consider some of the analogs:
- Ciprobai - the average cost in Russia is 249 rubles, in Ukraine - 73 hryvnia,
- Tsiprolet - in Russia 115 rubles, in Ukraine - 38 hryvnia,
- Tsipromed - the price in Russia is 144 rubles, in Ukraine -45 hryvnia,
- Sifloks - in Russia 170 rubles, in Ukraine - 53 hryvnia,
- Ciprobid - the average cost in Russia is 110 rubles, in Ukraine - 35 hryvnia,
- The figure is the average cost in Russia is 299 rubles, in Ukraine - 87 hryvnia,
- Ифиципро - the average cost in Russia is 89 rubles, in Ukraineine - 26 hryvnia.
Reviews
Reviews about the use of the drug Tsiprofarm state about its positive effects in various eye diseases, in more detail with all the reviews can be found at the end of this article.