In the pharmacy today you can find a lot of different tools for the eyes.
Some medications are used not only in the treatment of various diseases, but also for the sake of their diagnosis.
Apparent dilatation of the pupil is necessary when examining the ophthalmologist - only they allow you to fully study the fundus.
Their set includes Irifrin BC.Consider this drug in more detail.
- 1. Instructions for
- 2. Contraindications and side effects of
- 3. Conditions and periods of storage
- 4. Price
- 5. Analogues
- 6. Feedback on
- 7. Conclusions
- 8. Useful video
Instruction for the preparation
Form release, composition
Irifrin BK is sold in drops dispensed by flakonchikam-plastic droppers with a capacity of 0.4 ml. One cardboard package contains 15 bottles.
This is a colorless or yellowish liquid, representing a 2.5% solution of the active substance - phenylephrine, as well as auxiliary components.
As follows from the abbreviation "BK", the preparation does not include preservatives, which reduces the risk of irritation and allergic reactions during use.
Pharmacological effects of
Phenylephrine is an adrenomimetic - an artificially produced analogue of norepinephrine. The hormones of this group have a strong vasoconstrictor effect.
With topical application, they locally act on the vessels of a particular organ, with little or no systemic effect on the entire body.
Getting into the conjunctival sac, phenylephrine is rapidly absorbed through the mucous membrane. This causes vasoconstriction, due to which often accompanies fatigue or irritation of the mucosa, reddening of the eyes. There is an expansion of the pupil. Fluid withdrawal is activated, due to this, intraocular pressure drops.
The mydrias caused by Irifrin BK comes after 10-50 minutes after the administration of drops in the eye and lasts about two hours. Much more quickly the blood vessels contract: for this, 30-80 seconds is enough.
Indications for use
The range of indications of Irifrin BK is quite wide. It is applicable as a medicine in such cases:
- Iridocyclitis( inflammation of the iris of the eye).
- Glaucoma-cyclical crisis.
- Red eye syndrome.
- Spasm of accommodation.
- False and genuine myopia.
In addition, this preparation is required for:
- Test for closed-angle glaucoma.
- Diagnosis of external and deep infection of the eyeball.
- Visual examination of the fundus - ophthalmoscopy.
- Preparations for surgical intervention.
Method of application and dosage of medication
Irifrin BK is injected under the eyelid with the help of a dropper.
In order to drip the drug, you need to pierce the needle or gently cut off the tip of the vial( when piercing the needle it is more convenient to gently squeeze a drop out of the resulting larger hole may be poured more than necessary), then, lifting your head up, pull the lower eyelidand squeeze out one drop of solution under it.
After the introduction of the drug for a couple of hours, it is forbidden to read, use a computer, and engage in other activities that require eye strain.
Irifrin BC contains no preservatives, therefore the opened bottle can not be reused, and even if there is some liquid left there, it is better to throw it out.
Depending on the pathology, the dosage of Irifrin BK may vary markedly. When therapy iridotsiklita drug is buried in the affected eye drop by drop 2-3 times per day.
This reduces the amount of effusion in the outer chambers of the eye and prevents the growth of synechia. The course of treatment usually lasts from 5 to 15 days, its duration depends on the degree of inflammation.
In the treatment of true and false myopia, a drop of Irifrin BK is injected into each eye at bedtime three times a week for a long( from a month) period.
The same schedule and dosages are used to eliminate the spasm of accommodation, then the drug is used throughout the period of increased eye strain.
For diagnostic purposes, when glaucoma is detected, one drop by drop of the drug is instilled. If the difference in intraocular pressure before the introduction of the solution and after the onset of resistant mydriasis is 3-5 mm.gt;the result of the test is considered positive.
In the diagnosis of the depth of the inflammatory process, one drop of Irifrin BK is also administered once. Here, the indicator is the time of the redness of the eye: if it passes in about 5 minutes, then the infection is considered superficial when it is stored longer - that is, the grounds to suspect a deep lesion of the tissues.
Interaction with other medicines
Injection together with atropine increases mydriasis and may lead to tachycardia.
The intake of MAO inhibitors is fraught with a strong jump in blood pressure, so in such cases, Irifrin BK is not recommended. It is important to remember that the risk of arterial hypertension persists for at least three weeks after the abolition of MAO inhibitors, since they have cumulative properties.
The same consequences and heart rhythm disorders are fraught with the use of Irifrin BK against the background of treatment with antidepressants and m-holinoblokatorami.
To pressure jumps, and its use with beta-blockers. The drugs-sympathomimetiki increase the vasoconstrictive effect of Irifrin BK.
Contraindications and side effects of
Irifrin BC is prohibited when:
- is an individual intolerance to constituents;
- with a closed-angle or narrow-angle glaucoma;
- senile age, burdened by diseases of the cardiovascular system and the brain;
- of hepatic porphyria;
- deficiency of glucose-6-phosphate dehydrogenase;
- of prematurity.
Cautiously appointed with hereditary anemia, diabetes, age less than 1 year and more than 65 years, on time after surgery and when wearing contact lenses.
Application during pregnancy and lactation is possible, but undesirable, as detailed study of the effect of the drug on the embryo and the release of the active substance with milk was not carried out.
Side effects of Irifrin BC can be both local and general.
Local includes pain and sting immediately after injection, conjunctivitis, edema of the periorbital area, the exit of the iris pigment particles into the anterior chamber of the eye, reactive myosis( a narrowing of the pupil resulting from mydriasis decline), and also a sharp jump in intraocular pressure.
Common side effects: dermatitis, hypertension, cardiac rhythm disturbances, pulmonary embolism( infrequently).In exceptional cases, there are such severe consequences as heart attack, stroke, vascular collapse.
Overdose
When the dose is too high, tachycardia, dizziness, nausea and vomiting, sweating, anxiety, sluggish weakened breathing occur.
No specific antidotes exist, treatment is symptomatic. Fentolamine has established itself well.
Terms and Conditions of storage
Shelf life of the drug in unopened vials is 2 years. The temperature should not exceed 25 degrees, it should not be accessible to children and protected from sunlight. Opened vials are not subject to storage.
Price
| Country | Price |
| Russia | The price of packaging in 15 bottles in Russia is approximately 500-600 rubles and significantly exceeds the price of most analogues |
| Ukraine | Ukrainians Irifrin BC will cost approximately 400-450 hryvnia |
Analogues
To the list of analogs Irifrin BCincludes its synonyms - drugs containing the same active substance, and analogs - similar in effect, but different in composition of medicines. The first ones are:
- Mesatone.
- Neosinephrine-Pos.
- Synephrine.
It should be noted that they are all much cheaper, so Mesaton's cost does not exceed 55 rubles.
The following preparations overlap in the field of application with Irifrin BK:
- Naphazoline;
- Vizin;
- Tetrisolin;
- Oxytetazoline.
Reviews about the medicine
Impressions that left Irifrin BC in the patients who used it, mostly positive. It is effective in spasms of accommodation, myopia, quickly removes symptoms of irritation.
Due to the fact that the drug is approved for use by children, many students with this tool succeeded in slowing the progress often arising from the training loads of myopia, eliminating unpleasant eye fatigue.
Migrating iridocyclitis patients also note very rapid relief after the first few instillations. However, not all drugs came up because of side effects and high prices.
Some were able to purchase cheaper analogs and undergo a course of treatment with their help.
Conclusions
Following the article about Irifrin BC, the following can be said:
- This is a drug with a very broad spectrum of action, well-established, but has many contraindications and a list of serious side effects.
- Contains no preservatives, so the likelihood of an allergic reaction is low.
- It is allowed to children and is often used to help schoolchildren maintain healthy eyesight against the background of training loads.
- If necessary, can be used by pregnant and lactating women.
- Costs more money on the basis of the same active substance and, if necessary, is replaced by them without any damage.
Useful video
This may help: