IVF in natural cycle

Carrying out in vitro fertilization takes place for several programs. Her choice will depend on the menstrual cycle, the patient's age and survey data. Implementation of IVF in the natural cycle of the most secure, but not always effectively. It should be understood, in some cases, a similar transfer of the embryo into the uterus, and what is the likelihood of a successful pregnancy under such circumstances.

Indications and Contraindications for IVF in natural cycle

EC IVF ovarian stimulation without or with minimal hormonal effects Suitable for:

• if the problem is caused by the conception of male infertility, provided young age (18-35 years);
• when there are regular monthly;
• If even after CR observed scant reaction (from one to three eggs);
• if history has information about weak or operated ovaries,
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• therefore pointless to use stimulants;
• when infertility is the fallopian tubes;
• when it is possible to get good embryos, but pregnancy does not occur due to a failure of implantation;
• if a woman's health condition is not contraindicated artificial fertilization, but are prohibited from using stimulants and other hormone therapy.

Among the major contraindications we should mention:

1. Age from 36 years. Due to the condition of the reproductive system likely to become pregnant the first time will be minimal, and will take more attempts, which do not have the time.
2. Male factor. If your partner weak sperm, they can provoke getting the wrong embryo in advance. But when a long protocol or stimulation it is possible to fertilize several eggs.
3. Additional reasons. This could include a couple who have bad habits (cigarettes, alcohol). Also, if the menstrual cycle observed unstable natural or absent ovulation.

Read the article at the link what day of the cycle, making replanting of frozen embryos IVF.

What is the procedure

It goes a lot of myths surrounding IVF in natural cycles, and what it is actually know a few women.

Under such a process mean doctors method of infertility treatment, in which only one egg (maximum of two) is punctured and fertilized for further transfer to the uterus.

The main difference from the standard program - the complete absence of hormonal drugs to stimulate ovulation and control cycle. In rare situations, medication is still used, but in very small doses.

Features of IVF on the background of the natural cycle:

1. It is not supported by the development of the endometrium.
2. Extracted enough material to work with.
3. If the puncture is not used anesthesia.
4. Virtually no complications and side effects.
5. The result is hard to predict.

Pros and cons of fertilization

In carrying out their own IVF cycle women are the following advantages:

1. Prevention of ovarian hyperstimulation.
2. Exception hormonal load on the organism.
3. Reusability protocol in the next cycle immediately after unsuccessful IVF.
4. No risk of occurrence of cancer tumors.
5. The cost of services is somewhat lower because of the use of low-cost medicines.
6. Increasing the chance of implantation due to the quality of the endometrium layer.
7. Minimizing stress on the body.
8. The impossibility of occurrence of multiple pregnancies.
9. No need to freeze the remaining embryos.

Any good clinic, which has decided to address a woman, be sure to talk about the shortcomings in the fertilization cycle without monitoring and stimulation:

1. The greater degree of success will depend on professional experience, which made the puncture and time chosen for transfer.
2. Follicles can not mature this month, due to which the process is interrupted.
3. Due to the sudden release of luteinizing hormone, follicle sac may break before taking the egg.
4. During puncture sometimes it is impossible to remove the oocyte.
5. Often the skilled unable to fertilize a female material.
6. There is a high risk of damage to the egg at conception.
7. Rarely women become pregnant the first time.

That is why all these issues are discussed only with reproductologist. The doctor will decide whether it is possible to carry out insemination in natural cycle or better use of hormonal support.

protocol schemes

There are several schemes IVF protocols in the natural female cycle. The difference lies in the degree of drug load on the body:

• Net protocol;
• modified cycle;
• modified scheme of the EC.

When the patient treated in a medical facility, they often want to protect your body from the effects. But this does not mean that you should insist on a completely clean circuit fertilization. The doctor on the basis of the state of the reproductive system and the results of previous procedures will select the best program.

Typical steps in the EC:

• Preliminary examination of the patient;
• primary US;
• monitoring of follicle growth and endometrium structure;
• tracking indicators of hormones;
• control ovulation approaches;
• holding a puncture;
• fertilization of the oocyte;
• cultivation of the embryo;
• transfer into the uterine cavity;
• monitoring of the patient.

Net protocol IVF:

1. Examination of the body after menstruation begins.
2. About 7-8 days the doctor observes the growth of the follicular sac.
3. Control LH performed when the follicle becomes a diameter of 15-16 mm (learn when and on what day of the cycle to be tested for PH).
4. You can take blood tests or conduct tests for ovulation.
5. Carrying puncture will be done no later than the day after the positive test on luteinizing hormone.

The modified cycle IVF:

1. Conducting follikulometrii for 7 or 8 hours.
2. Once the follicle increases up to 17-18 mm in diameter, requires the injection of hCG.
3. Hormone creates conditions similar to the situation at the peak of LH.
4. As soon as the egg matured, held aspiration of the follicular fluid. In most cases, this procedure is carried out through 30-34 hours after entering the body of the hormone.

The modified scheme IVF EC:

1. Tracking follicle growth begins in the same way as in the first two schemes.
2. When follicular bag is 15 mm in diameter, the doctor prescribes a GnRH antagonist.
3. After blocking the spontaneous ovulation FSH is administered within a few days to successfully matured follicle.
4. Introduction of human chorionic gonadotropin is assigned when the follicle size of 18 mm.
5. Further, through the puncture is performed 28-34 hours.

Sometimes without stimulation IVF in the natural menstrual cycle does not give the proper result. Therefore, doctors decide on the implementation of the program of insemination small amount of hormones, to increase the chance of successful aspiration, fertilization and embryo transfer.

Possible situation with IVF

low AMH

After passing the tests and obtain the patient's disappointing results reflect on stimulation. But even if women drink Clomid, the quality of the eggs do not improve. Therefore, when the EC should think about the donor oocytes.

elevated FSH

Fertilization will only be possible after the stimulation or elimination of the factors that caused the increased content of the hormone in the body.

endometriosis

If the EC persists a great chance of success, but only under the condition of normal ovarian reserve in women. Also artisan can assign cauterization or removing the disease foci.

Where to go for the procedure

Choose a clinic for IVF on the reviews in the natural cycle is inappropriate. Patients may be frustrated by an unsuccessful result, or in any protocol unforeseen situations (premature ovulation, the egg is bad), which experts warned in advance.

Evaluate the performance of the medical institution and experience of hard, but it's better to do it during the consultation. And to help in the following factors:

• the physician must conduct a comprehensive diagnosis;
• a woman does not give a 100% guarantee;
• proposed several variants of fertilization;
• Specialist necessarily talks about the possible consequences.

Previously it was thought that the best clinics are only in major cities. But this area in recent years has greatly improved in the country, so finding a suitable place can be almost any woman.

probability of success

Most women are interested in who got pregnant after IVF performed in the natural cycle. A positive result without medical influence occurs less frequently than with the long protocol. Most often, this happens because of the following factors:

1. Premature rupture of the follicular sac.
2. The absence of an egg in the follicle.
3. Having low percentage of successful fertilization resulting material.
4. Transferring non-viable embryo.
5. Performing premature puncture.

According to statistics, the procedure has the following characteristics at the EC:

1. Pregnancy in 7% from the first manipulation.
2. Successful fertilization and embryo transfer increases the chance of implantation of 16%.

In most cases, you need a few tries. If the EC is not time consuming, because the body does not need a respite. If the first attempt is unsuccessful, the doctor reviewing the protocol and can add:

• preparations for egg maturation;
• medicaments for preventing premature ovulation;
• stimulating substance to obtain multiple oocytes.

Any information from forums and other websites should not affect the choice of a woman relating to the implementation of IVF at the EC. You can not predict or provide guarantees for successful fertilization and implantation. It is necessary to be patient and trust the expert to increase the chances of a long-awaited pregnancy.