Content
- Features and indications for use
- Structure and mechanism of action
- The main components
- 17 beta-estradiol
- drospirenone
- Excretion
- Release forms and instructions for the use of Micro Angelique
- Contraindications and side effects
- analogs
- Doctors about Angelique micro
- Reviews of patients
Climax - extinction is a natural process of reproduction, which occurs after 45 years. He is due to the fact that the body's reduced production of certain hormones, which affects the work of all organs and often appears uncomfortable symptoms. Early signs appear on the background of psychosomatic medicine, but in most cases - it is the consequences of the imbalance of hormones. In this case, experts designate antiklimaktericheskie agents: vegetable and synthetic; hormonal and homeopathic. At the current pharmaceutical market, of whom there are hundreds, but not all of them are effective. The greatest effectiveness is famous for hormone replacement therapy (HRT), and Angelica Micro relates to means for the therapy.
This article sets out the reviews about the drug Angelique Micro and especially its use in menopause.Features and indications for use
Long-term experience of Medicine has shown that the most effective means to relieving menopause It is HRT. The period of cessation of fertility is characterized by hormonal imbalance; some hormones are in short supply, the other - in an excess. To equalize this imbalance, experts prescribe hormonal treatments that contain the missing hormones. T. e. when the body alone can not develop the estrogen, it is introduced artificially into the organism as synthetic hormones that simulate its action and effect on the body.
Angelique Micro drug is often used in hormone replacement therapy. In its composition includes synthetic hormones that enters the body, it is converted into natural hormonal substances and perform their functions. Thus the body returns to its usual operating mode. This helps to eliminate the symptoms of the menopause such as irritability, mood swings, apathy, stress, causeless sadness, fatigue, hot flashes, profuse sweating, Palpitations, racing blood pressure and body temperature, pain in various parts of the body, brittle bones, a marked aging of the skin and so on. Also surfactants tools help stop degeneration of the reproductive system and stabilize the menstrual cycle.
Structure and mechanism of action
The main components
The main active ingredients of the medicament are:
17 beta-estradiol
Component which is a synthetic analog of the human estradiol, provides a replacement of the hormone before, after and during menopause. Estradiol is the most influential among the hormone estrogen. Its activity is associated with the work of the hypothalamus, pituitary, female organs, bone tissue. It is responsible for maintaining the desired concentration in blood insulin and glucose, for normal density of vessel walls and the correct operation of the heart muscle wall. Thanks to him, the bone mineral density indicators are normal.
Experts say that long-term use of pills Angelique in menopause significantly leads to normal bone health and helps prevent fractures and prevent osteoporosis. The substance helps to fill the depleting collagen, returns the elasticity of the skin and reduces wrinkles. But studies have shown that only one estrogen therapy may develop in menopause adenomyosis and as a consequence - cause the development of tumors in the endometrium. It is for this reason means includes a combination of progestagenopodobnye substances.
drospirenone
A synthetic hormone similar to progesterone exhibits action derived from spironolactone. It shows progestin, antimineralokortikoidnym, antigonadotropnym and androgenic function. It is responsible for the normalization of blood pressure by removing excess sodium and water, which also provokes the swelling, breast discomfort. The substance has anti-androgenic properties, which helps to prevent baldness and weight gain.
The combination of these hormone-like substances significantly reduces the level of cholesterol in the blood. Already after the first course of the receiving means decreases the risk of endometrial cancer, and colon cancer.
Excretion
It is noted that estradiol is fully absorbed, and soon enough. Metabolized to estrone, estriol and estrone sulfate, it occurs mainly in the liver, kidney, intestine, skeletal muscles and genitals. Bioavailability of 5% is reached already after 28 hours after drug administration. Complete necessary concentration in the body is achieved after 5 days of admission. Output by the kidneys and intestines.
Drospirenone is quickly absorbed fully. Bioavailability is 75-85%. For the most part metabolized and excreted through the kidneys and intestines. The highest concentration is also evident after 5 days of admission.
Also, the drug Angelique plus in small doses, contains magnesium and iron, which also has a beneficial effect on the relief of most symptoms of menopause.
Excipients are corn starch, and pregelatinized maize, lactose monohydrate, magnesium stearate, povidone.
Release forms and instructions for the use of Micro Angelique
The medicine is available in tablet form yellow, which have a circular shape, convex on both sides. Have a film coating. Inside the tablets are white.
How to take Angeliq in menopause right? Before application of the drug necessary to apply to the skilled person and undergo a comprehensive diagnosis to exclude a number of diseases that are contraindications for the use of tablets. The right dosage means may also determine a doctor, taking into account the characteristics of your body and during menopause.
Take medicine can be immediately after the end of therapy other hormonal substances (again, with the doctor's permission).
Packaging contains 28 tablets. Instruction requires reception of 1 piece per day in the same time by mouth with water. Drink tablets can be, regardless of food consumption. It is recommended to avoid missing medications. If this happens, you need to drink it as soon as possible, but if it has been more than a day, then another pill should not drink, as this can cause excessive vaginal bleeding.
Contraindications and side effects
Note that, like all the hormonal treatments, this one - has a vast number of contraindications. This includes:
- Hypersensitivity of any of the means components.
- All kinds of breast tumors or suspicion on them.
- Hormone-dependent tumors or symptoms.
- Vaginal bleeding and unusual nature of unidentified causes.
- All kinds of diseases or malignant liver tumors.
- Impaired renal function, their disease, as well as renal and adrenal insufficiency.
- Angina, thromboembolism, acute arterial thrombosis or a high risk of these diseases.
- Venous thromboembolism or deep vein thrombosis, susceptibility to these diseases.
- Hyperplasia, porphyria.
- Lactose intolerance, congenital or hereditary lactase deficiency, glucose-galactose malabsorption.
- Pregnancy and lactation.
- Only after thorough diagnosis and resolution specialist should take medication when endometriosis, uterine fibroids, diabetes, gall bladder, hypocalcemia, bronchial asthma, epilepsy.
It is necessary to eliminate smoking in the therapy and the use of alcoholic beverages.
Side effects were observed only in 4% of patients. They can be expressed in a variety of allergic reactions, vaginal bleeding, abdominal pain, lack of appetite, as well as headaches, dizziness and smearing vaginal secretions.
In the case of self-medication and no exclusion of certain diseases and contraindications, this means can cause the venous and arterial thrombotic complications, as well as unwanted tumor.
It is not recommended to combine the drug with menopause Angeliq with other hormonal medicines or pills take as contraceptives.
Overdose can cause profuse uterine bleeding, Gastrointestinal disorders such as vomiting, nausea, flatulence, diarrhea.
analogs
At the moment, there are a lot of foreign and domestic funds antiklimaktericheskih. They are different in their composition and form of release. Someone is a fan of homeopathy or plant hormones, such as Menopace, Remens, Klimaksan. Others rely only hormonal and HRT, thanks to their maximum efficiency and integrated action. Among hormonal therapy Angeliq Plus analogue composition in terms of the combination of hormones is only Femoston. However, the former is more popular due to the greater concentration of hormone in the drug, and as a consequence - the greater efficiency.
Doctors about Angelique micro
Opinions of medical professionals about the medicine Angelique at the climax vary. Some categorically rule out hormone replacement therapy due to a number of contraindications and the presence of tumor risk, other firmly believe in its effectiveness.
Gynecologists say that it is not always possible to timely detect certain diseases, the symptoms of which are similar to the symptoms of menopause at all its stages. Yes, and hormones with the onset of menopausal It is changing so quickly that during the survey and destination therapy clinical picture may change radically, and appointed drugs will not only not effective, and may even hurt and provoke the development of serious diseases and worsen It is. Therefore, doctors, assigning this medication, take into account and compared with the possible risk of the intended use.
But those experts who nevertheless chose hormone therapy, completely eliminating contraindications in their reviews say 95% success rate in its application.
On the application of this tool, experts allocate it to the background of the other due to maximum efficiency.
This drug is prescribed as to maintain the body in the during artificial menopause. But one thing is always the opinion of the doctors agree: Do not use this tool as a contraceptive.
Reviews of patients
Among female representatives Angelique medicine is very popular with the menopause, because the vast majority of those who use it, feel its positive and effective result.
Patients in the first place, mark the normalization of psycho-emotional state, which significantly improves the quality of life in this period. According to the reviews of Angelique in women who began taking it disappears irritability, lethargy, drowsiness, bad mood and climacteric neuroses, Life takes on new bright colors, back, and even increased performance.
It reduces the number of, and often completely disappear painful hot flashes, which replace often comes chills, trembling or profuse sweating.
After taking the drug, most women have lost brain, spinal pain as well as pain in the pelvis. Stopped aching joints and bounced back musculoskeletal system.
Almost all of the fair sex enjoy noticeable rejuvenation of the skin and fewer wrinkles, firmness and elasticity of the skin. Has returned to many of libido, improved quality of sexual life, disappeared dryness and irritation of the genitals.
It is safe to say that in the absence of contraindications Angelique Micro will become effective and useful tool in the fight against manifestations of menopause and improve health during this period.