Increasing CA 125 - the norm in women with cysts. Identification of glycoprotein marker does not indicate the beginning of a malignant process, but only at a certain concentration. With the growth of its level of development can be suspected adnexal cancer proliferation and other entities on these organs.
Content
- The clinical picture analysis
- Causes of increased CA-125 in blood
- How to prepare for tests for tumor markers
- Analysis CA 125 cancer appendages
- CA 125 levels during pregnancy
The clinical picture analysis
Tumor marker CA-125 - this protein is a glycoprotein, which is in every body, but only in small quantities. With the development of these tumors are elevated. Such data are often signals about ovarian cancer and other oncological diseases, inflammation of the reproductive system penetration infection in organs of the urogenital system, the development of endometriosis, and liver diseases.
Through this analysis fails to identify a malignant process in the initial stage of its development. If the protein increase was insignificant, then reappointed analysis in different period of the menstrual cycle. Due to this, it can not confirm the presence of abnormalities or exclude them.
Often increase the level observed in glycoprotein sprawl cysts. Excessive amounts of this substance leads to the beginning of neoplastic transformation process. Normally, at this disease indicators do not exceed 35 u / ml.
A large concentration of protein signals of serious pathologies. In order to identify them under further investigation.
Causes of increased CA-125 in blood
Upon detection of cysts appendages analysis shows the result of not exceeding 35 u / ml. At the time of the menopause it becomes even less - 20 U / ml... Within 110 U / ml level glycoprotein appears when development of the following pathologies:
- chronic pancreatitis;
- endometriosis;
- inflammation of the fallopian tubes or appendages;
- infectious diseases of the urogenital system;
- pleurisy;
- chronic form of hepatitis B;
- myoma;
- peritonitis.
If the analysis results of the parser 125 shown over 100 u / ml, then it is possible the development of lung cancer, ovarian, and as tubal mucous layer genitals, liver, breast, stomach and other authorities.
Higher rates can signal a benign and malignant processes in the body. For an accurate diagnosis under further investigation.
How to prepare for tests for tumor markers
To determine the tumor marker CA 125 with ovarian cyst, inflammation, cancer and other pathologies of venous blood sampling is performed. To get the most accurate results, it is imperative to adhere to the following rules:
- Rent stuff in the morning and only on an empty stomach. Since the last meal at the same time must pass a minimum of eight hours.
- No drinks except water for eight hours before the blood sample can not be consumed. Coffee and even tea can significantly affect the outcome. This will show a false presence of cancer cells in blood.
- A woman should be in a calm state, and not to worry.
- During the three days prior to the collection of material need to abstain from alcohol and tobacco use.
- Avoid exercise and massage for a few days before the procedure.
- Exclude the day before the delivery of the analysis of the use of fatty, marinated, salted and smoked products that can increase the level of glycoprotein.
- It is necessary to take into account the menstrual cycle. Hand over blood tests during menstruation It can be a couple of days after the end of regulation.
In addition, in preparation for the procedure, it is recommended that the admission of drugs. If this is not possible, then you need to put in the doctor's reputation and talk about the preparations that have been used in this period.
Analysis CA 125 cancer appendages
To identify the proliferation of malignant and benign tumors, defined by the marker level in the blood. In the presence of Oncology protein concentration usually increases. On the malignant cells more signal metrics 120 u / ml. The higher the level of glycoprotein, the more severe the disease.
Often an increase in protein concentration is observed at relapse cancer process. Reducing these parameters occurs after surgery or chemotherapy.
Assay for determination of tumor marker is one of the most reliable methods for diagnosis of ovarian cancer, fallopian tubes, as well as other malignancies. With it possible to detect a relapse at an early stage. The first clinical manifestations of disease are noted only a few months later.
CA 125 levels during pregnancy
In the first trimester of gestation period there is a significant fluctuation of hormonal levels. Rebuilt while the entire body. The fruit is able to produce tumor markers, whereby during the CA blood analysis study 125 protein level indicators are higher than normal. Cause for concern in this case.
For an accurate diagnosis is not enough to consider the level of CA 125 in women with ovarian cysts. To determine the nature of ovarian tumors, conduct additional research. Taken into account the woman's age, history of comorbidities, taking drugs. Is not always a high concentration of tumor markers in the body of pregnant women indicates a malignant processes.
A blood test to determine the level of glycoprotein - one of the most accurate methods of diagnosing cancer. Detect abnormalities using it possible to well before the onset of disease symptoms. This results in a timely initiation of therapy and to avoid unintended consequences. Decipher the results should only doctor. Quite often, an accurate diagnosis is assigned a number of additional studies.