CA 125 with ovarian cyst: the norm and deviation, decoding results

Analysis of tumor markers - an effective method for the detection of cancer processes. CA-125 - a protein that is incremented in values ​​in epithelial cancer appendages. However, there is a possibility of increasing CA 125 units with ovarian cysts. Norm in benign entities should not be higher than 100 IU / ml.

Important! Glycoprotein CA125 - specific antigen ovarian cancer. Slight jump in units occurs during menstruation, at an early stage of pregnancy, endometriosis.

antigen testing is only available when there is suspicion of malignant change appendages. Subsequently repeated checks are assigned cancer patients to control tumor growth dynamics, the evaluation result of therapy, prognosis of recurrences and metastases formation.

What is the tumor marker CA-125

CA-125 - a protein that is produced from the fetal skin cells. Its components can be detected in the cells of the pelvic organs, lung, pancreas, liver, intestine.

Protein analysis is not informative for the primary diagnosis. On the 1 st stage of the disease it rises only half of the women.

Tip! The test for CA-125 makes for a gynecologist direction, if it is assumed malignant process. In other cases it is better to use other methods of diagnosis.

When conducting a study

Testing for CA-125 is assigned for staging and diagnosis.

The main indications for screening:

1. Ovarian cancer.
2. Tumors of the uterus.
3. The growth of the endometrium.
4. Lungs' cancer.
5. Cancer of the stomach, liver, intestines.
6. Control outcomes.
7. The symptoms of relapse.
8. Other processes of unknown etymology.

A wide range of diagnoses of diseases caused by antigen epithelial origin. Excess serum antigen standards may indicate not only for cancer - there are a number of pathologies sensitive to the antigen.

How to prepare for the analysis for tumor markers

To perform a blood test CA-125, is a fence of venous blood in the morning on an empty stomach. When ovarian cysts women must report their diagnosis.

The results to be valid, you must implement the following recommendations:

• 3 days prior to analysis to remove from the diet, alcohol, spicy, salty, fried foods;
• stop heavy exercise;
• stop taking the medicine;
• not to do the test in the days of menstruation;
• eliminate smoking in the delivery day.

Ovarian tumor marker CA 125: decoding results

High rates of tumor marker CA-125 does not always indicate the progression of ovarian cancer. They can produce both false positive and false negative results. When interpreting serum antigen reference values ​​are taken into account.

Border analysis value of up to 100 U / ml is often detected when ovarian cyst. Exceeding the permissible hallway CA125 values ​​may indicate a serious inflammatory, neoplastic processes. The final conclusion can be drawn only after additional screening tests (ultrasound, MRI, biopsy, histology).

Elevated CA 125 with ovarian cyst

test in healthy women the results should not be higher than 35 units. Values ​​from 35-100 units. indicate the existence of pathologies such as: adenomyosis, endometriosis, polycystic acute adnexitis.

Comment! Blood test for CA 125 with ovarian cyst antigen shows high values ​​of specific damage to the follicle epithelial cells.

Increasing tumor marker CA 125 units - not uncommon when ovarian cysts. However, accurate diagnosis is possible only after a thorough diagnosis.

Norma ovarian tumor marker CA-125

For the interpretation of the results are set acceptable standards.

CA-125 numeric values. Table

U measurement	The reference	border	excess
CA 125 IU / ml	0-35 IU / ml	35-100 IU / ml	100 IU / ml

It should be remembered that the result from 40 to 100 units. It is not the norm and speaks of serious diseases of appendages or other organs. Any figure above 35 IU / mL - a reason to undergo a thorough examination.

What indicators CA 125 in ovarian cancer

CA reading study 125 - a good tool for dynamic monitoring in assessing and predicting the cancer process. Patients suffering from ovarian cancer antigen quantity is 120 - 200 IU / ml. 1-2 stage of the disease above normal is observed in only 50% of women. In the last stages of the SA 125 is increasing in almost all patients. When metastasis may exceed the value of 300 units.

Improving cancer protein speaks about the progression of the malignant process. Final decoding and evaluation of test results is carried out taking into account the characteristics of instrumental and clinical studies.

Reasons for rejection

Excess specific antigen CA 125 can be detected during the following pathologies:

• benign tumors;
• cysts;
• endometriosis;
• cirrhosis;
• Oncology other organs;
• autoimmune diseases;
• adnexitis;
• hepatitis;
• pancreatitis.

conclusion

It is important to remember that there is considerable potential for increasing CA 125 antigen in ovarian cysts. Norm established by the WHO does not always indicate the presence or absence of cancer. analysis figures may slightly exceed the reference values. Analysis of tumor markers should be performed only in the direction of a physician.