Content
- 1 Causes
- 2 Existing risk factors
- 3 disease
- 4 etiopathogenesis
- 5 What are the epithelial cells metaplazirovannogo
- 6 smear samples for diagnosis
Metaplazirovanny layer cervical epithelium represents the normal cells that are in the transformation region. If no abnormalities and pathological processes in the epithelium metaplazirovannom detected during diagnosis cells of different maturity. Experts note islands of columnar epithelium, which has open and closed types of glands, and normal vascular pattern.
Immature stage metaplazirovannogo epithelium indicates the pathological processes in the cervix, which require a thorough diagnosis. Under metaplasia refers to the change in the basic properties of the fabric. cervical metaplasia diagnosed mainly in patients older than 45 years. This disease refers to a precancerous condition, so delayed treatment can lead to serious complications.
In the absence of therapy healthy cells are gradually beginning to turn malignant.
It is for this reason it is important to start treatment at an early stage of development. Gynecologists recommend regularly come to the preventive inspection and planned to do screening.
Causes
The most likely causes of cervical metaplasia - is the spread of infectious agents. In the role of pathogens are the bacteria and viruses. A dangerous viral agent - a human papilloma, which penetrates into the woman's vagina. The main danger lies in the fact that this infection can have long asymptomatic and clear signs. Another possible agent - herpes, which has a high level of tumorigenicity.
After hitting metaplazirovannom pathogenic bacteria in the lining of the cervix begin to occur irreversible consequences. Women need to fear Ureaplasma, Chlamydia, Neisseria gonorrhoeae, Toxoplasma, and other microorganisms which penetrate into the cells and stored therein for a long time. They are repulsed by immune cells and maintain inflammation.
Existing risk factors
There are several common factors that lead to pathological changes in the cervical epithelium metaplazirovannom:
- bad habits (alcohol and smoking);
- poor environmental conditions;
- eating carcinogenic foods.
These factors help to reduce reactivity, so women develop functional and morphological changes in organs, as well as complete systems.
Higher risk in women who had early sex, multiple partners, doing abortions and asked for help to the gynecologist with hormonal disorders.
disease
Pathological changes in the cervix occur in many women. Cancer is a common and frequently occurring gynecological diseases. For pathological processes characteristic of staging and phasing of carcinogenesis. Diseases are divided into several varieties.
- Background. This disease of the vaginal part of the cervix, while the progression of which is preserved the integrity of the epithelium metaplazirovannogo, its differentiation, and maturation of exfoliation. These dangerous diseases include polyps, leukoplakia, papilloma, cervicitis, true erosion, ectropion and endometriosis.
- Precancerous. This group of diseases relates metaplazirovannogo epithelial dysplasia and other pathological processes. They contribute to the development of hyperplasia, proliferation, differentiation violation. As a result of these processes mature and rejected metaplazirovannye epithelial cells.
To prevent infection in the reproductive organs need to keep track of vaginal hygiene and regularly come for a visit to the gynecologist.
etiopathogenesis
Disturbances in metaplazirovannom cervical epithelium in most cases, lead to the fact that patients develop cancer stratified squamous epithelium.
These processes are related to the fact that the cells have Bipotential properties, so often turn into flat and columnar epithelium.
There are several ways of developing ectopic columnar epithelium:
- redundant cells are formed on the surface of the cylindrical metaplazirovannogo epithelium;
- gradual replacement metaplazirovannogo flat epithelial erosion, which have microcracks or inflammatory processes.
Metaplasia is a process resulting in redundant cells are converted into a flat shape metaplazirovannogo epithelium. Squamous metaplasia characterized by proliferation of reserve cells, which promotes the development of malignant transformation. By the formation of dysplasia or precancerous condition results in complete coverage metaplazirovannogo cylindrical epithelium.
What are the epithelial cells metaplazirovannogo
Cells metaplazirovannogo immature epithelium during diagnosis have the form parabasal. Chromatin is distributed evenly in the female body. In rare cases, during diagnosis skilled possible to determine the illumination zone. Cells are clear and smooth border on one side.
After the cytoplasm matures, it takes on a lighter color and an oval shape. Metaplazirovannye cells that have matured, have no differences from the squamous epithelium. Invasive form of cancer is a benign pathology. It is diagnosed in many patients who seek help from a doctor. That treatment yielded positive results need to begin therapy in a timely manner.
cytological screening It helps identify even slight changes and precancerous lesions.
the initial shape of the neck of the uterus cancer can be cured with radiation and surgical methods. Scientists have repeatedly conducted epidemiological studies, which have shown that pathological changes in metaplazirovannom lining of the cervix begin to develop as a result of conducting early sexual activity, with frequent changes of partners, smoking and drinking alcoholic drinks.
Infection affects topsheet metaplazirovannogo cervical epithelium resulting from the development of warts. This multiple papillary excrescences, which are composed of fibrous tissue. Formed on its surface metaplazirovanny stratified epithelium. Warts are flat, gabled, enlarged and inverted. Such pathological disease often occurs with no obvious clinical manifestations, so it is important to regularly come to the screening and diagnosis to the gynecologist.
smear samples for diagnosis
High-grade material for the study metaplazirovannogo cervical epithelium is considered to be of high quality swab. It contains squamous cells and endocervical. The defective material is a stroke during the study which it is impossible to determine the pathological changes in the cervical epithelium metaplazirovannom. It is important to follow all the rules during the swab to conduct a full investigation of the patient.
There are several reasons why the taken material is considered defective:
- negligent taking of smear;
- cervix reflected badly in the gynecological mirror;
- not complied with the conditions of taking material for the study of the state of metaplazirovannogo cervical epithelium;
- thin or thick smear;
- insufficient coloring material;
- contained in a smear of blood elements;
- poor material distribution taken glass;
- in a smear should be no particles antibacterial cream, lubricant with a condom, gel for ultrasound and spermicidal creams.
Investigation of the state metaplazirovanogo cervical epithelium is an important step to assess the health of the woman. Only after a comprehensive diagnosis gynecologist can prescribe the effective treatment.
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