Symptoms and signs of endometrial uterine cancer

Cancer of the endometrium of the uterus - the most common tumor disease of malignant nature. Pathology often seen in women who turned fifty-year milestone. The main cause of endometrial uterine cancer are considered to changes occurring during menopause.

Signs of a precancerous condition

Malignancies in most cases, are formed on the background of hyperplastic symptoms. Abnormal condition is associated with a local or total growth of the endometrium. In healthy women monthly is rejected the inner layer of the uterus, which then comes out with menstrual blood. Sometimes there is no rejection of the endometrium and on the background of this form of atypical structure, having the ability to transform into cancer cells.

atypical hyperplasia in medicine is considered a precancerous condition.

Women who have been diagnosed with "hyperplasia", and having a concomitant metabolic abnormalities and endocrine balance is necessary 2 times a year, a pelvic exam. Endometrial cancer, detected in the early stages of development, has a better prognosis for a full recovery.

Symptoms in stages

Symptoms of cervical cancer occur depending on the stage of disease development. In the initial stages of cancer symptoms are mild, but in the past - express themselves clearly.

stage 1

In step 1 Endometrial uterine cancer in women hormonal failure is present, and increased production of the hormone estrogen. All this causes a lack of ovulation and the presence of cysts in the ovaries. Specific bright clinical picture with the disease is absent. Women who are planning a pregnancy, there is infertility. And also characterized by heavy menstruation, the highlight color is dirty-brown, may be acyclic bleeding. Suspect the problem may be due to the complex laboratory tests. US - unreliable method for determining the initial stage of oncology. Reliable signs are during hysteroscopy.

stage 2

The second degree of pathologies characterized by the presence of symptoms and signs of possible endometrial cancer. Endometrial hyperplasia and polyps, which takes place against the backdrop of malignancy, manifest themselves as follows:

• uterine bleeding;
• bloody discharge during sexual intercourse;
• menses color meat slops;
• purulent discharge from the vagina;
• regular pain in the lower abdomen;
• appetite loss;
• nausea.

Cancer in step 2 may be suspected by ultrasound on endometrial thickening of its inhomogeneous structure, the presence of inclusions and characteristic changes in the reproductive organ cavity (presence of fluid).

The main way to detect disease in the early stages of development is hysteroscopy with biopsy, the study of uterine aspirate, biopsy, performed by various methods. US considered only as an auxiliary diagnostic method.

stage 3

In the third stage of endometrial cancer revealed precancerous uterine endometrial changes in functional or basal layer. In addition to the symptoms of the first stages of cancer join the following:

• general deterioration of health;
• the feeling of squeezing the abdominal cavity;
• vomiting;
• intense abdominal pain.

During ultrasound gynecologist can observe in the uterine cavity formation of considerable dimensions, having their own network of vessels. Diagnosed cervical lesion, regional lymph node metastases can be present in the bones, liver, lung, brain stem.

Endometrial cancer is the third stage of a poor prognosis for survival. The average five-year survival rates are 30% of patients.

Another characteristic feature of the disease in its advanced form - metastasis to neighboring reproductive organs and tissues. In step 3 uterine cancer often affects the fallopian tubes, parauterine space, sometimes ovaries.

stage 4

In the fourth step in the uterine cavity is formed with a malignant tumor invasion into the underlying body layers. Cancer cells spread through the body of a woman with lymph and blood flow. Symptoms are pronounced:

• constant weakness;
• chronic increase in temperature to 37.5 degrees;
• vaginal discharge mixed with blood, not associated with menstruation;
• signs of intoxication;
• stomach ache;
• problems with urination.

The metastasis necessarily involved not only the vagina, cervix, but also distant organs - the mammary gland, liver, kidneys, bone marrow. On US specialist clearly sees education with uneven borders and heterogeneous structure.

US complement hysteroscopy, laparoscopy, CT and MRI, histological examination for more accurate detection of pathology and the stage of having a metastasis in the body.

Symptoms Pathogenesis

Symptoms also appear, depending on the cause of the cancer. The causes of endometrial cancer is divided into estrogen-and estrogennezavisimye. In the first case, the tumor development is associated with increased production of estrogen.

The increase of estrogen in the body is diagnosed 70% of women with endometrial cancer of the uterus.

Malignancy resulting from Hyperestrogenism, takes place on the background of the following symptoms:

• weight gain;
• infertility;
• malfunction of the adrenal cortex (hirsutism, hyperpigmentation, acne);
• uterine bleeding;
• delay menopause;
• pathological changes ovarian structure (PCOS).

Because of the increased level of the hormone arises the risk of tumors in the breast, ovaries and digestive organs.

Estrogennezavisimye factors pathology in 30% of cases can become a cause of cervical cancer. Tumor mass is formed due to endometrial atrophy genitals. The disease is characterized by:

• high speed dissemination of metastases into adjacent tissue and organs;
• occurrence of heavy and prolonged bleeding;
• poor differentiation;
• difficulty in selecting a suitable therapy method.

uterine cancer may have a genetic cause of development. Women who are at risk, it is recommended to regularly visit the gynecologist and pass all required examinations.

semeiography

The disease has several characteristic features. Each of them is shown depending on the degree of progression of endometrial cancer and the individual characteristics of the patients (age, genetic predisposition, body).

uterine bleeding

Bleeding from the genitals - the main symptom of cancer of the uterus. The clinical picture of the disease manifests differently in women of different ages. Meager or copious observed in 90% of cases with illness.

Bleeding in women of reproductive age may indicate cervical pathology, failure of hormonal regulation of the menstrual cycle, endometriosis. For this reason, the correct diagnosis only by the symptoms is difficult.

Uterine bleeding in postmenopausal period - a clear sign of developing endometrial cancer. Due to this manifestation of the pathology to diagnose a malignant tumor is possible in the early stages of development.

whites

Beli - the second most common symptom of endometrial cancer, which is most evident when the new formation of considerable size. When running pathology stages of whites are abundant. Accumulation of mucus in the uterus causes regular pulling pain in the abdomen, similar to the discomfort during menstruation.

If whites accumulate in the uterine cavity, the clinical picture is supplemented by the following features:

• by pain Expander nature;
• body temperature rise;
• febrile syndrome;
• total degradation.

For endometrial cancer is characterized by watery discharge. When joining a secondary infection from the uterine bleeding or purulent allocated clots. Upon decomposition leucorrhea tumor cells become putrid smell unpleasant.
pain

Pain syndrome bothers most women in the last stages of cancer of the uterus, in the propagation of abnormal cells in the pelvic organs. When squeezing ureter tumor discomfort appear in the lumbar region, the symptoms resembling renal colic. If the tumor is large, it may compress the rectum or ureter, becoming a cause:

• pain during defecation and urination;
• frequent urge to the bathroom;
• TENSO - urgency to defecate without isolation of feces.

Symptoms of uterine endometrial cancer vary depending on many factors: the cause of the tumor, stage of disease and individual characteristics of women. Pathology quite difficult to detect in its early stages, because at this stage there is no typical clinical picture. Ultrasonography is also not a reliable method for determining tumor, therefore its complement hysteroscopy, histological analysis or biopsy. The only symptom that allows you to identify a problem - uterine bleeding.

In the later stages of cancer symptoms appear brighter. Women celebrate at the general deterioration of health, temperature rise and signs of intoxication. Pathological condition is accompanied by pain in the abdomen and whiter release. Detect the presence of tumor, its location and size is possible by ultrasound, CT or MRI. Diagnostic laparoscopy method complement near laboratory tests to determine the type of tumor and the possibility of metastasis to other organs and tissues.