Analysis on a chlamydia in pregnancy: a smear, PCR analysis of blood

Prenatal care includes a number of a number of studies that exclude various diseases that may adversely affect the condition of the woman and the fetus. Analysis of chlamydia during pregnancy to determine the condition of the urogenital area on time and to appoint competent treatment.

Do I have to be tested for chlamydia during pregnancy

Chlamydia is relates to the prevalence of pathology, its distinguishing feature is called asymptomatic in the early stages. Pathogens - Chlamydia. Microorganisms represent bacteria, predominantly sexually transmitted and causing the infectious nature of the disease.

Do not identify specific symptom does not mean the absence of chlamydia, which represent a danger during pregnancy. In order to avoid infection with the registration of the pregnant woman is sent to diagnose chlamydia. In some cases, it requires additional studies to identify the type of chlamydia and determine their sensitivity to antibiotics.

Analysis of Chlamydia included in the mandatory list of diagnostic tests performed during pregnancy. This is due to dangerous consequences for both mother and fetus, which sometimes occur on the background of progressive disease.

Chlamydia can cause these diseases, including during pregnancy:

• the formation of adhesions in the pelvic area;
• spontaneous abortion;
• localization of the ovum outside the uterine body;
• late toxicosis;
• violation of patency of the fallopian tubes;
• premature birth;
• Reiter's disease.

Lack of timely diagnosis, which implies the implementation of tests, treatment and neglect can cause the following complications of the fetus:

• infection with lesions of the fundus;
• anoxia provoked by metabolic disturbances;
• Chlamydia pneumonia;
• congenital conditions.

Important! Blood test for chlamydia in pregnancy to avoid the development of dangerous complications on the part of the mother's body and fetus.

Indications for delivery of analyzes on a chlamydia in pregnancy

Chlamydia is transmitted through unprotected sexual contact. The rapid infection of the female reproductive system of departments related to the ability of pathogens to attach to the cells and spread.

Attention! The medical literature describes the cases of infection through everyday during pregnancy. In such cases, infection with Chlamydia occurs during the use of certain items of personal hygiene.

The most dangerous vertical route of transmission of chlamydia observed during pregnancy. It involves the infection of the fetus. Infection is due to the penetration of chlamydia through them swallow amniotic fluid.

Performing research on chlamydia in pregnancy is shown in the following forms:

• unusual vaginal discharge (purulent, odorous);
• frequent and painful urination;
• pain in the abdomen;
• inflammation of the eyes;
• comorbidities urogenital zone;
• low-grade fever laboratory confirmed the presence of the inflammatory process;
• fetal abnormalities.

Attention! Required performance analysis for chlamydia in pregnancy due to possible lack of specific symptoms suggestive of infection process.

Types of tests for chlamydia in pregnancy

Reveal chlamydia during pregnancy is possible through the following diagnostic methods:

• serology;
• immunogenetic.

To determine chlamydia gynecologists prescribe the following tests, which are also shown and during pregnancy:

1. Bakposev. When collecting the biological material on the so-called culture media talk about conducting bacteriological seeding. As part of the analysis of the cultivated product lodge in the specially created fertile ground. Diagnosis is carried out with the addition of growth medium. Cell elements were incubated for 2 days. Determine chlamydia in cells can be obtained by PCR method.
2. Cytological examination. The analysis to determine the presence of inflammation.
3. amplification of RNA (Which are the basis for the implementation of cellular elements vital chlamydia). This new analysis, based on the determination of RNA chains in the biomaterial.
4. Enzyme immunoassay research. The method involves determining the presence of antibodies in serum to the pathogen infection. Analysis represents fence venous blood produced fasting.
5. Serological tests. The study is common in foreign clinics. Ready test antibody containing coating is different. The accuracy of the result does not exceed 70%.

When performing the analysis by ELISA of blood determine the presence and level of antibodies:

• IgM - primary infection;
• IgA - severe;
• IgG - chronic.

Experts recommend diagnose Chlamydia by PCR analysis. Polymerase chain reaction is considered a highly sensitive assay which reveals pathology at different stages of progression. Smear PCR for Chlamydia during pregnancy is taken from the vagina or the urethra.

At diagnostics specialist uses a sterile instrument called Volkmann spoon. With gynecological instruments carried fence vaginal mucus, which is applied to a glass slide. Of considerable importance is orderly during intake stroke to avoid damage to the mucosa and penetration of blood in test samples.

Under laboratory conditions, a specific dye coated sample for further examination under the microscope. Results of analysis on a chlamydia usually available within 8 hours. High information PCR is the lack of potential cross-reactivity observed with similar bacteria (structure).

How to be tested for chlamydia during pregnancy

Performing smear for chlamydia in women during pregnancy requires some preparation:

• the exclusion of sexual activity for 3 days prior to analysis;
• abandonment of the sauna before the procedure;
• discontinuation of the antibacterial agents (at least one week before diagnosis).

Before carrying out the analysis can not douche. urinary retention should be 3 hr.

When performing blood analysis to identify antibodies to chlamydia (ELISA method) preparation includes the non-use of drugs (antibiotics), alcoholic drinks. Blood sampling produced an empty stomach in the morning.

Important! To be tested for chlamydia during pregnancy can be in any trimester.

deciphering tests

The results of these studies is made in a special form. Decoding results varies depending on the method of analysis.

When the smear on Chlamydia trachomatis does not matter content of microorganisms. In this case, the analysis is considered positive for Chlamydia.

The following antibody variants indicate when decrypting ELISA analysis:

1. IgM-, IgG-. In this case, talking about the absence of infection in women during pregnancy.
2. IgM-, IgG +. Chlamydia is present in the form of a carriage or a pregnant woman has a corresponding immunity. Specific therapy is not required.
3. IgM +, IgG-. The analysis result of pregnancy for Chlamydia involves the acute phase of disease, which requires receiving antimicrobials.
4. IgM +, IgG +. Option indicates the intense work of the immune system against the background of the primary infection. Usually in this case it requires a specific therapy.

Attention! Treatment is carried out after receiving the test results, focusing on the clinical pathology data. Appointment of a course of therapy also depends on the identification of co-morbidities.

Treatment of chlamydia in pregnancy performed after 16 weeks of gestation. In this period marked the full functioning of the placenta protects the fetus from the negative effects of antibacterial drugs. Accepted drugs paralyze DNA and damage the membrane of the pathogen. Thus, appropriately prescribed treatment to prevent the spread of infection and prevent the development of dangerous consequences for the mother and fetus.

conclusion

Assay for Chlamydia during pregnancy is typically conducted by PCR. This is associated with high accuracy and safety diagnostics. In some cases, gynecologists recommend complementary examination performing ELISA for antibodies to chlamydia.