Content
- 1 The effectiveness of treatment of chlamydia azithromycin
- 2 Indications for Azithromycin for chlamydia
- 3 How to take Azithromycin for chlamydia
- 4 Contraindications and side effects
- 5 Precautionary measures
- 6 conclusion
- 7 Honest reviews of azithromycin from chlamydia
One of the most common bacterial disease is transmitted through sexual contact, is chlamydia. The disease is characterized by symptoms of poor or complete lack of, so it is difficult to detect in a timely manner. Often, doctors have to treat a chronic disease with antibiotics. In accordance with the standard scheme of therapy administered azithromycin for chlamydia. Its microbiological and clinical efficacy proven by multiple studies.
The effectiveness of treatment of chlamydia azithromycin
When bacterial infectious lesions for therapeutic purposes in dermatology often prescribe antibiotics related to macrolides. Azithromycin is indicated for patients who have been found uncomplicated urogenital infection caused by the action of Chlamydia trachomatis. The active ingredient of the drug is azithromycin. Means release tablets of 250 and 500 mg.
Azithromycin when ingested is rapidly absorbed from the digestive tract and accumulates in the tissues of the urogenital organs. The concentration of active substance in the tissue and in its cells is ten times higher than in blood. In addition, azithromycin accumulates in the phagocytes, which bring him to the place where the infectious process develops.
Regimen of azithromycin for chlamydia in women picked individually. It depends on the clinical symptoms of the disease, presence of concomitant infections. The doctor may recommend as a one-time use of large doses of antibiotics and courses lasting 3-5 days.
Scheme azithromycin treatment of men with chlamydia were not significantly different. But the appointment of the therapeutic course, doctors take into account the fact that the longer the infection is in the body, the more difficult to get rid of it.
The use of Azithromycin instructions indicated that for urogenital infections enough to accept 1 g once. The use of such a scheme is acceptable, if revealed an acute form of the disease. In chronic chlamydia antibiotics prescribed course over which should take from 3 to 12 g azithromycin. The maximum concentrations of drug administered to men who have been diagnosed chronic prostatitis urethrogenic caused by the action of chlamydia.
Most patients helping prolonged therapeutic regimens macrolide antibiotics in combination with immunostimulators. A single dose of Azithromycin for chlamydia does not give the desired result. Many patients have symptoms of the infection returning.
Important! In diseased tissue concentration of active ingredient 24-34% higher than normal. Azithromycin in the inflammation persists for 5-7 days after the last dose.
The effectiveness of azithromycin therapy in chronic chlamydia depends on the selected scheme. In conducting studies patients received 1 g once, followed by 0.5 g every two days. During the treatment of the people who participated in the experiment, you need to take 3 g of azithromycin. To accelerate penetration of the antibiotic into the tissue, to increase the effectiveness of treatment using parallel physiotherapy - phonophoresis hydrocortisone, laser, SMV-therapy.
Studies have shown that in 97% of patients during the first inspection, which is carried out 2 months after completion of therapy, fully or partially disappeared symptoms of chlamydial infection, microbiological study showed that the efficacy of treatment was 94,7%.
Repeated follow-up studies conducted after 6 months in patients who have shown that 97% of the symptoms were gone, and in 93% of chlamydial infection was not found in the study by PCR.
Experts identify such advantages of Azithromycin:
- drug efficacy above 93%;
- possibility to cure both asymptomatic infections or diseases in which clinical signs appear;
- ease of dosing;
- minimum number of contraindications and side effects of a rare occurrence;
- simultaneous action by concomitant sexually transmitted diseases.
According to research anti-chlamydia azithromycin may not be effective in patients with a rising form of infection. In such a situation requires more prolonged treatment with large doses of antibiotics.
Indications for Azithromycin for chlamydia
In accordance with the data specified in the operating instructions Azithromycin, it is administered to patients with diseases which are caused by Chlamydia trachomatis. They may be asymptomatic, in this case, to identify the infection only allows conducting microbiological research. One can not ignore the need for therapy, even asymptomatic chronic form of the disease. It can cause the development of inflammatory pathologies of the reproductive organs and lead to infertility.
When chlamydia may occur more than 20 clinical symptoms. Reveal his patients, and patients who were referred for examination in connection with the identification:
- cervicitis;
- cystitis;
- vulvovaginitis;
- urethritis;
- orchitis;
- prostatitis.
Comment! In 30-40% of women suffering from the inflammatory lesions of the genitourinary system, detect chlamydia. Up to 46% of chronic prostatitis and up to 34% of acute epididymitis develop as a complication of chlamydial urethritis.
If you have symptoms, indicating the development of inflammation in the genitourinary system organs, doctors recommend to get tested for STIs. In identifying the doctor prescribed chlamydia azithromycin drink. His patients are discharged as an uncomplicated and a complicated form of infection. They differ only approved drug regimen.
How to take Azithromycin for chlamydia
Patients who have confirmed chlamydia tests, therapy should be prescribed by a doctor. The instructions indicate that this is enough to accept venereal disease Azithromycin 1 g once. This corresponds to two tablets of 500 mg, or 4 to 250 mg.
But doctors recommend drinking Azithromycin for chlamydia is not according to instructions, and by individually preparing the plan. Often prescribe this drug in such a course:
- 500 mg on the first day;
- 250 mg daily from 2 to 6 days inclusive.
No less popular is the scheme that was used to assess the effectiveness of the means - 1 g on the first day and 500 mg a day as long as the body is not received 3 g active substances. Also, the doctor may prescribe drink for chlamydia 2 Azithromycin tablets of 500 mg per 1, 7 and 14 days.
According to the recommendations for uncomplicated form of the disease requires 3-5 g azithromycin. When resistant infections the dose can be increased to '12
Patients with rising chlamydial infections may nominate intravenous formulation of 500 mg over 2-3 days. In this therapy does not end, women are recommended to take 1 tablet of 250 mg for 5-6 days.
Tablets need to drink 1 time per day on an empty stomach. It is better to do it for 1 hour. before a meal or after 2 hours after a meal.
Contraindications and side effects
Azithromycin is not indicated for people who have intolerance to this drug or allergic reactions to other macrolides previously been identified. Also, it is not recommended for patients who have problems with the liver or kidney with signs decompensation.
Side effects are rare. Some diarrhea occurs, provoked by an increase in motor activity of the receptors.
Among other complications in the digestive system called:
- nausea;
- stomach pain;
- flatulence;
- cholestatic jaundice;
- vomiting;
- pseudomembranous colitis.
But there is a probability of occurrence and other complications, some people on the background of developing these side effects:
- skin rash;
- angioedema;
- headache;
- convulsions;
- dizziness;
- headache;
- general weakness;
- increased anxiety;
- vaginitis;
- candidiasis;
- photosensitivity.
When they occur should immediately consult a doctor, the doctor will make adjustments to the scheme of the therapeutic drug or replace if necessary.
Precautionary measures
People who have observed pronounced disorders of the liver, kidney, cardiac arrhythmia (elongation QT interval and ventricular arrhythmia), assign the macrolide antibiotic should be with caution. After completion of the therapeutic course of a hypersensitivity reaction may remain, so people need specific therapy aimed at normalizing state.
In applying Azithromycin for chlamydia side effects may occur in the nervous system in the form of sleepiness, dizziness. Therefore, at the time of treatment is better to abandon the road management and work with complex mechanisms.
Warning! When taking other medications must inform the attending physician. This is necessary to avoid negative interactions.
The concentration of the antibiotic in the biological liquids and tissues can grow while receiving Cyclosporine, terfenadine, hexobarbital. Anatatsidy, which contains magnesium hydroxide or aluminum, ameliorate azithromycin absorption and lead to the fact that the maximum concentration of antibiotic will be less than desired. Acceptance of this macrolide provokes increase digoxin concentrations while receiving.
conclusion
Azithromycin for chlamydia is the most commonly prescribed drugs. Its effectiveness is proven in the conduct of clinical trials. But before prescribing physician should make sure the patient has no contraindications to receiving. To evaluate the effectiveness of therapy is necessary to pass the tests in 2 months after the end of treatment. To make sure that the disease does not reappear, it is advisable to retake the analysis of six months.
Honest reviews of azithromycin from chlamydia
Titomirova Tatiana, 32 years old, Vladivostok
Results of the survey on STI have shown that I have chlamydia in the chronic form. For the treatment of a doctor appointed to take azithromycin 1 g once every 7 days, Proteflazid and Fluconazole. Control analysis after 6 weeks after the end of treatment revealed no pathogenic microorganisms.
Zavalska Maria, 27 years, Kazan
To get rid of chlamydia doctors prescribed drink 1 g of azithromycin once me and partner. All this time it was necessary to use a barrier method of contraception. Re-analysis showed that it was not possible to recover after 2 months.
Oksana Novikova, 31, Petrozavodsk
After treatment with azithromycin chlamydia symptoms disappeared. Feel better already on the 3rd day of taking the pills, I stuck to the doctor's recommendations and completely cutting drug on a designated course. Now we have to wait 6 weeks to get tested.
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