HCG on days after ovulation: growth, change (see table), when to take the analysis

Human chorionic gonadotropin is responsible for the stimulation of progesterone production process. His active runningaway starts with the implantation of the embryo, ie 6-8 days after fertilization. Progesterone appearing under the influence of human chorionic gonadotropin is an essential element influencing the maintenance processes, allowing the fetus to develop properly until such time as the placental wall will not on its own generate the necessary hormones. Normal levels of hCG levels are calculated by days from the occurrence of the last ovulation: they grow up to 13 weeks gestation.

What is HCG

On average 7 days after fertilization blastocyst is formed, representing the sphericity of the body, filled with liquid components. Its outer shell formed tens of cells, and is an indispensable element for creating the tissue from which a further development of the placenta occurs and toddler.

When interacting with the mucosa blatotsisty begins to produce hCG then constructed primary horonicheskie villi representing an initial stage of formation of the placenta.

HCG delivers signals yellow body and stimulates the production of progesterone, required for constructing the endometrium. Also, this process gives a signal to the pituitary gland that ovulation is no longer required due to the pregnancy. Basically, this function is activated horonicheskogo gonadotropin for 6 days after the release of the egg.

In the first week of childbearing study result has the following rule: every couple of days it doubles. If you develop a few fruits, the amount of the hormone is increased in proportion to their number. This growth in activity decreases with increasing gestational age.

Approximately 4 months after fertilization, progesterone begins to produce placental tissue, which is why hCG and function of the corpus luteum becomes irrelevant.

HCG levels in women after ovulation

Human chorionic gonadotropin is composed of alpha and beta subunits. To determine the presence of fetal beta tests used one, since it is unique to hCG. It is this unit is included in the concept of the norm.

Norm volume hCG after ovulation varies by day. Noticeable growth was observed at 8 hours he was 1.4 IU / L. After a day, it can be increased to a value of 5.3, but its normal minimum number set in similar previous days range. On the 10 th day after ovulation the amount of the hormone begins to actively grow: it will be a minimum of 1.9, while the maximum - 13.1 IU / L. With 11 days after ovulation, the following rules are established hCG:

• 11 hours - from 8 to 45;
• Day 12 - a minimum of 20 and maximum - 59;
• on day 13 the number increases to 33-91 IU / L;
• the rate of 14 days: 57-140 IU / L;
• Day 15 - a minimum of 100 and a maximum - 252;
• the next day normal rate increases to 156-433;
• 17 hours - at least 276, the maximum - 706;
• 18th day - from 473 to 1033;
• 19 day rate increased to 626-1384 IU \ l.

If at the end of the second week after ovulation content of HCG in the urine of less than 25 IU / L, this indicates that pregnancy has not occurred. When the volume exceeds the average value can be formed of several fruits.

HCG on days when pregnancy

In pregnancy, in the first half months after ovulation hormone concentration is doubled every 2 or 3 days. His maximum blood level is set at 10-12 weeks after conception: 50,000-100,000 IU / L. Then hCG growth process is suspended, its rate gradually begin to subside, Thus, for 140 hours it is set in the range 1000-20000 IU / L.

In first-time mothers female hormone levels during pregnancy grow up to 100000-200000. Established norms of growth hormone on the day of ovulation, they are listed in the table.

The number of weeks from conception	The value in IU / l
1 half of the month	HCG on day 10 after ovulation is set within 8-26 IU / L on day 11 of hCG rate: 8-45 IU / l. The minimum index ascertaining fetal development, is set in the range of 25 units, and the maximum - 156.
2-3 week	Optimum performance at 14 days after ovulation are within 101-4870.
The second half of the month after ovulation	Normal figures are 1110-31500.
4-5 weeks	Displacement hormone is set within 23100-151000.
5-6 weeks after ovulation	Minimum rate - 25600, while the maximum - 82300.
6-7	The optimal parameters are within 27300-233000 U / L.
7-11 week	hormone level minimum set at around 20,900, while the maximum - 291000.
11-16 weeks after ovulation	Normal values ​​are set at the minimum volume equal to 6140, and the maximum - up to 103,000.
16-21 week	The minimum rate is 4720, and the maximum - 103000.
21-39 weeks from conception	Number hormone is set within 2700-78100.

Reasons for change in hormone levels

Normal levels of hCG levels in urine and blood after ovulation may vary from that used for the diagnosis of laboratory equipment. If the analysis gives a result in 5-25 IU / L is required to re 2-3 days.

Most often in violation of the fetus or gestation indicates a decrease in hormonal output. Among them it can be diagnosed:

• backlog of normal values ​​of fetal development;
• perenashivanie;
• the death of the child;
• in the early stages it is able to talk about the ectopic fetus.

The low volume of hCG may indicate a lack of embryo appearance of the risk of miscarriage. Upon detection of such abnormalities woman appointed ultrasonography for diagnosis of possible violations. This is due to the fact that their own identify signs of miscarriage pretty hard.

The causes of increasing non-pregnant

Today, the result of HCG directly indicates the presence or absence of the child. But increasing the amount of this hormone in the blood and urine can also be caused by other reasons.

1. The most obvious reason is the recently interrupted or ending in pregnancy naturally. In this case, the amount of hormone in a woman's body will remain high for 2-3 weeks. Once he starts to decrease gradually.
2. Hormonal changes may contribute and receive medicines, which include human chorionic gonadotropin. For example, if a woman does an injection of hCGThen it becomes a cause of false-positive results in the diagnosis of the presence of the fetus.
3. Of all cases less specific - increase in the level of human chorionic gonadotropin in the presence of trophoblastic tumors. Such neoplasms contribute to the development of gonadotropin - a hormone capable of producing hCG.

If a woman received a false-positive test results, then she needs to see a doctor in order to exclude the likelihood of having abnormalities in her body.

Reduction in Pregnancy

In any trimester hCG may fall for several reasons. Most often, it is promoted by the following factors:

1. Ectopic pregnancy: no amount of the substance is increased as compared with the period of gestation, or to increase slightly. However, the woman can observe the signs of pregnancy or symptoms of toxicity.
2. Delay of physical development of the child.
3. Missed abortion: no increased amounts of the hormone.
4. The presence of placental insufficiency.
5. If the doctor asks about the occurrence of the last menstrual period, but the woman does not remember its exact date, the period of gestation may be determined erroneously. In this case, it may be diagnosed erroneous gap from the hormone level standards. Also, such a situation can be related to late onset of ovulation.
6. Perenashivanie fetus. This may indicate the emergence of serious pathologies of the fetus, so you need to carry out additional tests, making ultrasound, passing all the necessary tests.
7. abortion threat may appear due to the presence of genetic abnormalities in fetal development, hormonal imbalance in the female body, the presence of infectious diseases.

If the reduction in the number of human chorionic gonadotropin occurs on average every 7 days, a woman rushing on the ultrasound, lay in the hospital for safekeeping.

When to take a urine test and a blood hCG

For the diagnosis of the volume of this hormone can donate blood for hCG to 1-2 weeks after ovulation, and urine - from 1.5-2.5 weeks. Blood tests are allowed and after implantation - 7 DPO. In these days of the hormone will have a minimum performance. The number hCG on day 8 and day 9 should be determined by a blood test. This is due to the fact that HCG appears in the urine only after his blood level reaches a certain value, is fixed at 10-14 hours after ovulation.

The best option is considered blood donation, which is done to determine the level of this hormone with 1-2 days of menstruation. To exclude ectopic or missed abortion, this analysis is required to take an interval of 2-3 days. If it is carried out to diagnose successfully conducted an abortion, it should be done in 1-2 days after the medical intervention.

Preparation for delivery of analysis

In order to obtain reliable results, it is necessary to prepare for the analysis. This requires to comply with the following recommendations:

• take blood from a vein in the morning;
• Analysis done on an empty stomach;
• In the absence of a study in the morning, it can be done in the afternoon, giving up a meal for 5 hours before blood sampling;
• when administered any medication, especially if taken hormones, it should tell the doctor who issued the referral for investigation;
• before blood donation can not be physically overstrained, to have sexual intercourse.

The analysis results can be obtained in 2 days. If the analysis gave in the early stages - from 7-8 days after fertilization, hCG levels should be re-check in 2-4 days. This is due to the fact that in this period the content of the hormone in the blood, and even more so in the urine is minimal, so the study may give false negative or false positive result.