Tropicamide is an eye drop that is used to diagnose eye diseases and perform operations on the retina to expand the fundus. However, this drug has a large number of negative consequences for the body in case of incorrect application.
- Composition and Form of Use
- Indications for use
- Contraindications
- How to use
- Side effects
- Consequences of taking drops
- Analogues
Composition and form of release
Eye drops 0.5% and 1% clear, colorless. The main active substance of the drug is tropicamide 5 mg and 10 mg, respectively. Excipients: sodium chloride, disodium edetate dihydrate, benzalkonium chloride, purified water, hydrochloric acid.
Eye drops Tropicamide has a mydriatic and anticholinergic effect. Mydriasis( dilated pupil) develops 7-10 minutes after the drip and reaches its maximum effect after 20-25 minutes. The dilated pupil remains about 1 hour( when using a solution of 0.5% solution) and 2 hours( with a 2% solution instilled).The maximum paralysis of accommodation( adaptation of visual perception of objects at different distances) after double instillation of a 1% solution occurs approximately after 35 minutes and lasts 25-35 minutes. Complete localization of the paralysis of accommodation occurs in 3 hours.
Indications for use
- Examination of the lens and fundus.
- Determination of refraction.
- Surgical direction( surgical intervention on vitreous body and retina, extraction of cataracts, laserocoagulation).
- Inflammatory eye diseases.
- Prevention of the development of synechiae after surgery.
Contraindications
- Hypersensitivity.
- Glaucoma( mixed primary and occlusive).
- Intraocular hypertension.
During the treatment, eye drops should be careful to drivers of any motor vehicle, as well as when engaging in activities that require increased attention and speed of the psychomotor reaction.
to table of contents ^How to use
Drops Tropicamide is injected conjunctivally, slightly pressing the area of the lacrimal sac for several minutes.
According to the instruction, in the course of the diagnostic for dilating the pupil, 2 drops of Tropicamide 0.5% solution or 1 drop of 1% should be injected into each eye. After this, the examination can be done after 10 minutes. At low efficacy, a joint use with phenylephrine is possible.
To determine refraction by 1 or 2 drops, instill 6 times every 6-12 minutes. The examination is carried out after the onset of paralysis of accommodation, after approximately 30-60 minutes.
Children, including infants, are allowed to use only 0.5% solution. Preterm infants should dilute eye drops in a ratio of 1: 1 saline( to prevent the development of unwanted effects - violations of defecation, urination, tachycardia).
For therapeutic purposes, the physician determines the dose individually for each patient.
Side effects of
Eye drops can cause:
- Decreased visual acuity.
- Infringement of accommodation.
- Increased ophthalmotonus.
- Development of an acute attack of closed-angle glaucoma.
- Allergic reactions.
In addition, such unpleasant effects as excitation, anxiety, hyperthermia, dysuria, tachycardia can occur.
to table of contents ^Consequences of taking drops
Tropicamide is very popular among drug addicts, as it is sold without a prescription and is inexpensive. Drug addicts who used opiates dripped the means to dilate the pupils to hide drug intoxication from others, while causing side effects: psychomotor agitation, in some cases accompanied by hallucinations. It was often used intravenously in combination with other narcotic substances.
The hematopoietic system suffers, the level of hemoglobin becomes minimal, the nervous system is depressed, until the coma develops. A person suffers from epileptic seizures, his memory worsens, which often leads to mental retardation and insanity.
to table of contents ^Analogs
The main substance to the structural analogues of Tropicamide are Midrialzil, Midriaticum and Midrum.