How does the menstrual cycle change with the action of dexamethasone

In today's world it is impossible to imagine the treatment of many diseases without the use of hormonal drugs. In particular, a wide range of indications have glucocorticosteroids - analogues of substances that normally excrete adrenal cortex cells. To many people these preparations save a life, protect from invalidity. But in addition to the achieved therapeutic effect, this group of drugs has many side effects. And in many situations it is necessary to choose from two evils smaller. Do these drugs affect a woman's menstrual cycle and her ability to become pregnant? How is dexamethasone bound and delayed menstruation?

Contents

  • 1 Why is the preparation
    • 1.1 Effect on the links of immunity
    • 1.2 Use of anti-inflammatory properties
    • 1.3 For the correction of the hormonal background
  • 2 Brief instruction on the use of
  • 3 Effect on the cycle

Why is the drug

Dexamethasone is a synthetic analogue of hormones of the adrenal cortex. It is used practically in all fields of medicine. The drug has an effect on all types of metabolism: protein, carbohydrate and fat, which is very clearly traced when it is used for a long time. The main properties of the drug:

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  • anti-inflammatory,
  • desensitizing( reduces the production of antibodies in response to antigen in the body),
  • antiallergic,
  • immunosuppressive.

As a rule, rarely attention is drawn to how dexamethasone affects menstruation until the moment when a woman decides to become pregnant. And long-term administration of even small doses is detrimental to the reproductive system.

What is the purpose of the tool?

Effect on the links of immunity

With all autoimmune diseases, taking medication saves from excessive perverted response of the body's own cells. As a result, the number of antibodies on the body's own cells decreases.

Use of the anti-inflammatory properties of

This is the most common application of the drug. All eye drops, skin ointments contain a drug substance for this purpose. The effect of the drug is to reduce the local anti-inflammatory response. Dexamethasone and its analogs are widely used for the appearance of edema, for example, with exacerbation of hemorrhoids or candida colpitis( thrush).Immediately after laying on the candle, the pain and itching are relieved, it becomes much easier.

For the correction of the hormonal background

For this purpose, dexamethasone is used as a substitution therapy in violation of the synthesis of its own steroids, as well as to suppress the excessive synthesis of androgens - male sex hormones. Hyperandrogenemia can lead to infertility or late miscarriages at a period of 16 to 21 weeks.

With proper administration, dexamethasone can cause a monthly in a more or less adjusted rhythm along with other hormonal medications.

Quick Instructions for Use

The dose and method of administration depend on the disease in which the agent is used. This can be as a single intramuscular injection at a rate of 10 mcg / kg body weight, and a sustained, systematic intake of 10-15 mg / day to 5-10 mg / day. The following forms of the drug are common:

Form of preparation Indications
Injections Used in acute conditions, for example, with anaphylactic shock, Quinck's edema, severe infectious diseases and sepsis, asthma attack, with certain types of leukemia, joint diseases( inserted into the cavity), etc..
Tablets Appointed with adrenogenital syndrome, when, due to excessive function of the adrenal cortex, excessive amounts of androgens are released - male sex hormones, including polycystic ovaries. Tablets are also widely used during pregnancy, if a woman has severe signs of hirsutism, there have been disruptions and problems in her history( especially in the late term).Indications for the use of dexamethasone are Addison-Blimmer disease, when the adrenal glands "do not work," with Shihan syndrome - postnatal necrosis of the pituitary gland, as well as with connective tissue diseases( for example, systemic lupus erythematosus, rheumatoid arthritis, etc.) and many many ailments.
Ointments As part of various ointments that are used in dermatological and ophthalmic practice. It is thanks to this use of the drug that many diseases of this sphere can be introduced into a state of prolonged remission.
Drops This form is used in otorhinolaryngology and ophthalmology. Even ordinary drops from the common cold often contain dexamethasone or another glucocorticosteroid. Especially when it comes to allergic rhinitis and long-term use of the drug.
Candles Candles have found their application in proctology( especially in the treatment of hemorrhoids and anal itching), urology and gynecology. So, for example, many candles from inflammation in the vagina to achieve a quick effect and relieve itching and swelling contain dexamethasone.

It becomes clear that almost every woman at least once in life is faced with these dosage forms. Sometimes, when using the drug, the question arises whether dexamethasone can cause to delay the monthly, which happened precisely in the cycle of taking this medication?

We recommend reading the article about what to do if you delay the monthly. From it you will learn about the timing of menstruation, the risks and consequences of the cycle, folk methods for calling monthly, effective herbal remedies and medications.

Effect on the

cycle Local application of dexamethasone does not affect sexual and reproductive function. That's why doctors calmly prescribe ointments and drops, especially in courses.

Systemic exposure begins after prolonged use of even small doses, regardless of the mode in which the medication is used: pulse therapy, a constant dose, etc.

With a single, large drug use, for example, with Quincke's edema, there may be a slight malfunction in the cycle, as a rule, its lengthening, especially if similar adjustments have occurred earlier, but for other reasons. Dexamethasone and monthly - how are they interrelated? The fact that this drug with a long and systematic reception disrupts the process of maturation of the follicles, thereby causing various dysmenorrhea, until the appearance of menstruation only 1-2 times a year. Also, taking medication affects the level of TSH - a substance that regulates the functions of the thyroid gland. The developing clinic of hypothyroidism promotes the appearance of multiple small cysts on the ovaries, and disrupts the process of maturation of follicles. As a result, ovulation occurs only a few times a year.

But if the drug is taken at the clinic of hyperandrogenemia - increasing the level of male sex hormones, and the dosage is correctly chosen, then the menstrual cycle should only normalize, and the fertility should increase. In some women, conception occurs only after hormone correction by prescribing a drug.

Dexamethasone is a serious drug with a multifaceted effect. Saving many people from terrible, sometimes fatal consequences and complications of diseases, he has a number of side effects. Studying the properties of the medication, it becomes clear why the menstruation started after taking dexamethasone or, conversely, the cycle elongated to 60 to 90 days. The remedy can be used only according to the prescription of the doctor, named for the chosen scheme and dose.

  • Mar 16, 2018
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