Lavenum refers to drugs with pronounced thrombolytic effect. The agent is applied externally.
The main active ingredient in the drug is heparin, due to its high concentration, the drug helps to effectively combat the heaviness and swelling of the legs, prevents the appearance of thrombi, which can become the main cause of the development of varicose veins.
Content
- Pharmacological action
- Pharmacokinetics
- drug Indications
- Contraindications
- mechanism of action
- Instructions for use
- Overdose and the additional guidance
- Cautions
- competent opinion
- cost medications
- Available analogues
Pharmacological action
This tool refers to the anticoagulation groupdirect action.
The medicinal preparation is applied externally and has a local effect on the tissues, differs anti-edema, anti-inflammatory and antithrombotic properties. The drug helps to block thrombin, reduce the level of activity of hyaluronidase, and also leads to the activation of fibrinolytic properties of the circulatory system.
Heparin, a part of the drug, gradually penetrates deep into the skin, leading to a decrease in the inflammation focus, as well as the normalization of blood flow. Due to active microcirculation of blood, there is a resolution of blood clots, removal of puffiness and heaviness in the legs.
Pharmacokinetics of the preparation
Lavenum absorbed by the skin in an insignificant degree.
When applied externally, heparin enters directly into the circulatory system, after which it is biotransformed in the liver.
The maximum level of the drug in the bloodstream is fixed 8 hours after the application of the drug to the affected skin. For removing the drug from the body, the kidneys respond.
Indications for use
Due to the high content of heparin, the agent has an effective effect in many cases associated with the formation of troughs and the violation of normal circulation in the limbs.
Main indications for the use of the drug:
- Periphlebitis and thrombophlebitis of superficial veins .The medicine can be used both for treatment and for the purpose of
effective prevention of such diseases. - Very effective in the presence of hematomas , as well as severe bruises of joints and soft tissues.
- Edema of localized type and infiltrates of soft tissue surface.
- Elephant .
- Surface mastitis .
Contraindications to the use of
The drug has some contraindications for use, which include:
- The drug is not allowed to use for ulcerative necrotic changes in the skin of the , or their trauma.
- Any violation of the integrity of the skin in places of approximate application of the drug is a serious contraindication to its use.
- Low coagulation of the blood .
- Individual hypersensitivity of to the active ingredients of the drug.
- Thrombocytopenia .
- The drug categorically is prohibited for use with open bleeding wounds or active stage of purulent processes.
- The is not applied to the mucous surfaces of the skin .
- Drug should not be used in children with , as there are no clinical studies on use for children.
Mechanism of Action
The drug is applied to the skin externally. When applying medication, heparin is absorbed into the bloodstream within 30-60 minutes and spreads through the bloodstream throughout the body, contributing to the reduction of inflammatory processes, the reduction of edema and soreness in the extremities.
Heparin in the formulation effectively fights with the formation of blood clots. It is excreted from the body by the kidneys.
Instructions for use
The gel is applied to the affected areas of the skin with a thin layer. On skin integuments about 5 cm in diameter, 5 cm of the drug is applied. The medication is applied 1-3 times in 24 hours.
The frequency of application of the drug depends on the intensity and stage of the inflammatory process. As a rule, the drug is recommended to be used for 3 to 7 days.
Lavenum is available in the form of a colorless or light yellow gel for external use. The main active ingredient is heparin sodium 1000 IU / g.
Form release: uel with a specific odor in an aluminum tube 30, 50 or 100 mg, in a carton.
Auxiliary components: methyl parahydroxybenzoate, ethyl alcohol rectified, carbomer, lavender essential oil.
Overdosage and additional indications
No cases of overdose with this medication have been recorded, since the active substances in the formulation have low absorption values.
The use of this medication during pregnancy is not prohibited. But the medicine should be used under close medical supervision.
The relationship between the application of the gel and the negative consequences for the unborn child has not been established reliably. The use of the drug is recommended in the case when the benefits for women significantly exceed the risk to the fetus.
Lavenum has some interaction with other drugs.
This medication is not recommended for use with non-steroidal anti-inflammatory drugs, antibiotics from the tetracycline category, and antihistamines. It is forbidden to use the medication simultaneously with other drugs for external use.
Drug is strictly prohibited for use in the treatment of children younger than 6 years of age .Information on the use of this gel for older children is not available.
Special instructions
The drug should be used with extreme caution in the presence of thrombocytopenia.
It is also not recommended to use this medication with the bleeding of wounds located at the sites of the intended application of the gel.
With special care should be used medikametnoznoe remedy for wounds of an open nature, as well as purulent abscess on the surface of the skin.
The drug is not used for deep vein thrombosis, increased vascular permeability, and it is strongly advised not to apply the drug to the mucous surfaces of the skin.
Data on the effect of the drug on the ability to drive vehicles or complex mechanisms are not available at this time.
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Competent opinion
The doctors' comments on Lavenum use are given below.
I always recommend to my patients to use this drug as a prophylaxis of venous disease of the lower limbs.
Due to the high content of active substance - heparin, the preparation perfectly normalizes blood circulation and prevents the appearance of thrombi.
Ivan Konstantinovich, Moscow
To me, patients with circulatory disorders in the lower extremities, strong bruises and subcutaneous hematomas of soft tissues are regularly treated to me.
To accelerate the healing process, this gel perfectly suits - it promotes rapid resorption of hematomas and restores the normal condition of the skin.
Galina Y., Ekaterinburg
And the opinion of patients.
Olga, Sochi
I work as a salesman. The whole day on my feet, by the evening I feel terrible fatigue. The only salvation is Lavenum. I put the gel on the skin of my legs - and I take off my fatigue.
In addition, the gel is an excellent prevention of varicose veins. But do not put the tool in the presence of open wounds - the consequences can be the most negative.
Elena, Kaluga
Medication cost
The drug is available in the form of a gel with a transparent texture or a slight yellow tint. 
The average price in pharmacies is 170-180 rubles .The medicine is allowed to leave in pharmacies without a prescription. This drug should be stored in a dark, dry place, which provides unavailability for children.
The optimum temperature for storing the drug is not more than 25 ° C.
Available analogues
Lavenum analogues include such medications:
- Lyoton;
- Heparin;
- Trombleuss;
- Heparin-Acrigel;
- Venitan-forte;
- Heparin ointment;
- Dolobene-gel;
- Venolife;
- Contractbucks;
- Troxevasin neo.