Glivenol and Glivenol procto are medications that are designed to treat serious diseases such as varicose veins and the acute stage of hemorrhoids.
The drug is one of the most popular angioprotectors, whose action is aimed at eliminating the causes of varicose veins.
This drug has two main active components - lidocaine and tribenozide.
Due to the presence of these unique components, the drug has a pronounced anti-inflammatory, venotonic, strengthening effect.
Glivenol-Procto belongs to the number of ultramodern modifications of the drug.
Unlike its predecessor, the drug is intended for the rapid and effective treatment of hemorrhoids, as well as the advanced stage of venous stasis. The main active substances in the composition of this drug are tribenozide and lidocaine.
Contents
- Pharmacological action
- Pharmacokinetics of the drug
- Indications for use
- When the drug is not recommended
- Mechanism of action
- Instructions for use
- Forms of release
- Overdose and additional indications
- From the practice of using
- Medication cost
- What to replace?
Pharmacological action of
The presence of such active components as tribenozide and lidocaine in the above medicines leads to a decrease in venous stasis, a marked improvement in microcirculation in the area of the affected blood vessels, and strengthening of the capillary walls.
Drugs have a local anesthetic effect, as well as the ability in the shortest possible time to reduce the manifestations of any inflammatory processes.
These medications are effective in combating increased vascular permeability.
Pharmacokinetics of the drug
Procto Glyvenol is available in the form of capsules for internal use, as well as in the form of a cream for external use or rectal suppositories.
In all forms of these drugs, the main active substance is tribenoside.
In the rectal administration of the drug, the body absorbs about 30% of tribenozide from the amount of active substance that enters the body by oral administration of the drug.
After the introduction of the rectal suppository, the maximum level of concentration of tribenozide in the blood is reached after 2 hours after taking the medication.
Active substance enters the metabolism in the liver and is excreted directly from the body by the kidneys.
Indications for use
The drug is recommended for use in such cases: 
- various violations of venous circulation in the lower limbs;
- varicose veins, provoked by increased permeability of blood vessels;
- feeling of heaviness, fatigue in the legs, and swelling of the lower limbs;
- venous congestion, a variety of phlebitis, trophic ulcers of the shins.
Procto-gliwenol is used in cases of the need for treatment of internal and external hemorrhoids, as well as in the presence of the most neglected stages of hemorrhoids.
When medication is not recommended
Procto Glivenol is a safe drug and has very few contraindications, which include:
- The drug is not recommended for taking during the first trimester of pregnancy .
- If there is an individual intolerance to one of the constituent components of this medication, you should immediately stop using it. Hypersensitivity of the body is one of the main contraindications to the use of drugs in the form of capsules, as well as suppositories.
- Medication is not recommended for use in patients under the age of 16 years old .To date, there is no reliable information on the effect of the drug on the children's body.
Mechanism of action
The mechanism of action of these drugs is completely based on the pharmacological properties of the active components that make up their composition. The main active substance is tribenoside, which belongs to the group of synthetic glucofuranosides.
This unique substance is an active antagonist of numerous factors that lead to the onset of inflammatory processes, as well as increased permeability of blood vessels.
Tribenozid is quickly absorbed by the body and spread by the circulatory system across all affected areas.
For oral or rectal use, the drug has a pronounced anti-inflammatory, anti-edema and analgesic effect, contributes to the normalization of microcirculation and a decrease in the indices of venous stasis.
Instructions for Use
Procto Glivenol, available in the form of capsules or dragees, is recommended to take 800 mg 4 times daily .The drug should be taken with food wholly without chewing.
It is allowed to take a capsule or a dragee with a few sips of water. The duration of the course of treatment is determined by the treating specialist and can not be less than 3-4 weeks.
A medication in the form of a cream or suppository is recommended to be used twice a day, in the morning and in the evening, regardless of the meal.
The drug is used externally. After removing the acute pain syndrome, you can reduce the dosage to once a day, at bedtime.
Forms of release
The product is manufactured:
- In the form of capsules or pellets, 20 or 100 pieces of in a carton. The concentration of active substance in each capsule is 400 mg, and the dragee is 200 mg.
- Rectal preparation is made in the form of cream for external use, 30 mg each in an aluminum tube. The active substance concentration level is 50 mg of tribenozide in one mg of cream.
- Also, the preparation is manufactured by in the form of rectal suppositories of 400 mg .In a cardboard box there are 10 candles.
Overdose and additional indications
The drug may cause certain side effects:
- a variety of disorders and disorders in the normal functioning of the gastrointestinal organs - nausea, vomiting, constipation, heartburn;
- allergic reactions of the skin that can be expressed in the form of redness, rash, severe itching;
- with external use of rectal cream can cause pain and itching in the area of application.
This medication is also not prescribed for breastfeeding. The same limitations have a cream for external use.
These medications should not be prescribed on their own - this should be done solely by the attending physician based on the complete clinical picture of the disease.
Not used to treat children and adolescents under 16 years of age.
At the moment there is no reliable information about cases of overdose with these drugs.
In case of accidental ingestion, immediately wash the stomach and take a special sorbent.
These medications are not used in the presence of liver failure.
From the practice of using
Reviews of doctors and patients who used the cream and suppositories of Procto Glivenol.
I have been suffering from hemorrhoids for a long time. During periods of exacerbation of the disease I use a cream for external use and feel instant relief.
I tried a lot of different drugs, but it was Glivenol-procto who came up to me just perfectly.
Vasily, Nizhny Novgorod
After delivery, she noticed the first manifestations of hemorrhoids. Very unpleasant phenomenon, but on the Internet I read reviews about this drug and decided to try it. The pain disappeared after a few days, I feel much better.
Natalia, Samara
I advise all my patients with exacerbation of hemorrhoids within a few weeks to take this medicine. This drug actively reduces the manifestations of the inflammatory process, promotes the disappearance of hemorrhoids, strengthens the walls of the capillaries.
Victoria, Yekaterinburg
Medication cost
The drug is available in the form of capsules or dragees of 20 or 100 pieces per pack. Depending on the number of capsules, Glivenol's price fluctuates within 150-1000 rubles .
The cost of rectal suppositories - about 500 rubles, cream - about 400 rubles.
These medicines can be bought without a prescription. Keep drugs should be in a dark and cool place at a temperature of no more than 25 degrees Celsius.
Than to replace?
Glivenol analogues are drugs Avenok-plus, Proctosan, Sulgan.