Application in the stomatology of a solution for injections Ubestesin

Ubistezin( Ubistesin) refers to drugs that have a local anesthetic effect. The drug is one of the most modern and effective representatives of a group of local anesthetics.

Ease of use, a small amount of preservatives and adverse reactions allowed ubistine to become a choice option in the presence of somatic pathologies in the patient. Dentists widely use anesthetic for conductive and infiltration anesthesia.

Components of anesthetic and features of carpules

The formulation contains:

• articaine hydrochloride 40 mg;
• epinephrine hydrochloride or epinephrine;
• water for injection;
• sodium chloride;
• sodium sulfite.

The product is available in 2 versions: ubistezin 1/200000 and Forte version 1/100000.They differ in the amount of vasoconstrictor. In the first case, the amount of epinephrine will be 5 μg / ml, and in the second - 10 μg / ml.

The anesthetic itself is made in the form of carpules with a volume of 1.7 ml. They are packed in special tin cans with a soft surface from the inside.

Due to this, the integrity is preserved during transportation, and further storage takes place without any complications.

In this case, each individual carp has its own peculiarities:

1. Surface coating with a special silicone layer .As a result, the injection becomes smooth and controlled, the piston moves more gently, and the amount of applied force is much less.
2. All the necessary information is printed on the cartridge with the marking tape , which replaced the printing on the glass. Accordingly, the risk of splinter damage in case of its destruction has decreased. This moment is very important in the conduct of intraligamentary anesthesia, because the pressure in this case is very high.

Pharmacological properties of

All properties of the drug are achieved through the main active components: articaine and epinephrine.

Articaine refers to local anesthetics of the amide type. Its effect comes in 2-3 minutes after the administration and lasts approximately 50-60 minutes. In comparison with older substances, for example, novocaine or lidocaine, the action of articaine is twice as strong.

Also, it is quickly excreted from the body, does not increase the wound healing time and has less toxicity. Therefore, ubistezin can be used for elderly people, pregnant women and children over 5 years.

Epinephrine is responsible for the vessels. It has a vasoconstrictive effect, which significantly increases the time of anesthetic effect.

Due to this component, the drug has a high penetrating ability and almost completely binds to blood plasma proteins. This ensures the safety of its use in the treatment of pregnant and lactating women. The medicine does not enter the breast milk and does not penetrate the placenta.

Scope and contraindications

Anesthetic is used for intraligamentary, infiltration and conductive anesthesia during the following dental procedures:

• tooth extraction;
• treatment of surface and middle caries;
• root canal cleaning;
• dental treatment for orthopedic constructions;
• operative interventions on the mucosa of the oral cavity or bone;
• closing of the message between the maxillary sinus;
• cyst removal;
• installation of metal plates for jaw fractures.

Ubistezin and the more so Ubestezin Forte can not be used with:

• individual intolerance of the drug components;
• paroxysmal ventricular tachycardia and atrial tachyarrhythmias;
• hyperthyroidism;
• closed angle glaucoma;
• application of nonselective beta-blockers;
• severe forms of hepatic insufficiency;
• bronchial asthma;
• treatment with tricyclic antidepressants and preparations containing monoamine oxidase;
• cardiogenic shock;
• of methemoglobinemia;
• B12-deficiency anemia.

Conditions in which the use of the agent should be carried out with caution:

• deficiency of cholinesterase;
• kidney failure;
• diabetes mellitus;
• hypertension;
• children under 4 years.

How is the medicine administered and in what dosages?

The method of administration and dosage of anesthetic depends on the goals of the dentist:

1. In the treatment of uncomplicated caries of the right jaw , the preparation is inserted into the transitional fold from the vestibular side. The injection volume is 1.7 ml. In some cases, an auxiliary use of an anesthetic from 1 to 1.7 ml is allowed to obtain the maximum anesthetic effect. The injections from the sky can not be performed. Anesthesia is used for the extraction of teeth on the upper jaw.
2. Injections from the palate are used by in the course of incision and suturing in the oral cavity of the .The optimum amount of anesthetic is 0.1 ml.
3. If manipulation is performed on the lower jaw of , then a normal infiltration anesthesia with a volume of 1.7 ml is sufficient in the treatment and removal of the frontal group of teeth and premolars. If necessary, an additional injection of 1-1.7 ml is performed. If the desired effect has not been achieved, then a complete block of the nerve of the lower jaw is carried out.
4. In the treatment and removal of lower molars , conductive anesthesia is always done. The optimal amount of the injected substance is 1.7 ml. If necessary, the preparation can also be injected into the transitional fold.
5. Preparation of the tooth for root canal filling or its treatment for the installation of orthopedic structures is performed under infiltration anesthesia. The dose is 0.5-1.7 ml.

Use in special cases

Due to the low content of the vasoconstrictor, the risk of side effects is low enough. Therefore, the use of medication in the treatment of patients with diseases of the cardiovascular system is not excluded.

When pregnancy Ubistezin can be used, it has no harmful effect on the fetus. Only in rare cases develops a bradycardia. The drug of choice in such situations is a medicine in a dosage of 1/200000.

Special instructions

Intravenous administration is completely excluded. To prevent such situations, an aspiration test should be performed.

The drug can not be used in the field of a pronounced inflammatory process. It is recommended to inject the product near the inflamed area.

To prevent the development of infections, needles and syringes need to be changed during each fence from a vial or ampoule. Open carpules are not reused. Also, the use of damaged cartridges is excluded.

Possible adverse reactions and cases of overdose

Ubestezin can have the following depressing effects on body systems:

1. Effect on the CNS .The patient may develop headache, loss of consciousness, respiratory failure, convulsions.
2. Effect on the digestive tract .In some cases, nausea, vomiting and diarrhea occur.
3. Changes in the work of the senses are observed rarely .Sometimes, in violation of the technique of anesthesia, diplopia or temporary disturbance of visual acuity is possible.
4. Effect on heart and blood vessels .There is a possibility of lowering the level of arterial pressure, tachy- or bradycardia, arrhythmia.
5. Allergic reactions .On the skin may appear hyperemia and itching. There is also a risk of allergic conjunctivitis and rhinitis. Of the more serious complications, there are angioedema and anaphylactic shock.
6. Local manifestations of .At the injection site, edema or an inflammatory reaction is possible. If there is a violation of the procedure for anesthesia, there are zones of ischemia and damage to the nerve trunk occurs.

Symptoms of excessive drug administration are:

• dizziness;
• change of consciousness;
• lowering of blood pressure;
• tachy- or bradycardia.

What to do if unwanted reactions occur:

• Immediate stop of drug administration;
• giving the patient a horizontal position;
• providing with oxygen;
• pulse and pressure monitoring;
• for breathing is recommended the introduction of ducts and artificial ventilation;
• if there are cramps, then barbiturates are used;
• circulatory disturbance is corrected by solutions of electrolytes;
• bradycardia is treated with intravenous injection of 0.1 mg of epinephrine;
• for tachycardia uses selective beta-blockers;
• pressure is reduced by peripheral vasodilators.

Cost and analogues

The price of the Ubestezin Fort solution is 1500-2000 rubles per 50 carp, the drug in a dosage of 1/200000 is 1800-2200 rubles per packing.

The following medicines have similar pharmacological properties:

• Alfacaine;
• Bilocaine-epinephrine and Brilokain-adrenaline Forte;
• Artikine;
• Primacaine;
• Septanest;
• Ultracaine DS and Ultracaine D;
• Scandinavian.