Varicose is a common disease that affects both women and men. Varicose veins are transmitted by heredity, in women - during pregnancy or taking hormonal medications, in the case of a sedentary lifestyle, increased venous pressure and obesity.
Treatment of this disease is performed surgically, using sclerotherapy or medication. One of the best medicines for varicose is the Avenue pill.
Avenue is tablets of a convex oval form of pink-brown hue covered with a shell. In one package there are 3 or 5 blisters.
Contents
- Pharmacological and pharmacokinetic effects
- Indications for prescription
- Features of application
- Overdose and adverse reactions
- Other data
- Indications for pregnant and lactating
- Consumer opinion
- Useful information in doctor's reviews
- Terms of purchase and storage
- Analogues of Russian origin
Pharmacological and pharmacokinetic effects
Pills belong to the group of capillary stabilizing agents with bioflavonoids, diosmin, combinationth and ATC code S05SA53.
They contribute to increase venous tone, reduce stretch marks, visibility of capillaries, improve microcirculation of lymphatic drainage.
A venotonic agent helps to reduce the negative effects of inflammation on the veins and their valves.
The drug acts for 11 hours, after which a large number is excreted from the body with the help of the intestine, with urine leaving about 14% of the dose taken.
1 tablet contains 500 mg of the flavonoid fraction in a purified and micronized form( in terms of 100% anhydrous substance).It includes 450 mg of diosmine, which is 90% of the total mass and 50 mg of hesperidin - flavonoids, which is 10%.
Indications for prescribing
Avenue medication is used to treat symptoms of venous insufficiency of the legs( heaviness, pain, swelling in the legs, convulsions) and hemorrhoids. 
In acute hemorrhoids, this medication will not be replaced by a specific treatment, and will not affect the treatment of other proctologic diseases. If after a short course of treatment, the symptoms do not disappear, you should consult a specialist and be examined.
For the effective treatment of varicose veins, it is recommended to combine therapy with a lifestyle:
- does not stay in the sun for a long time;
- prevent the propensity to obesity;
- to give less weight to the legs;
- walking;
- use special stockings to improve blood circulation.
Taking Avenue is contraindicated in case of hypersensitivity to active or auxiliary substances.
Features of the application
The drug is administered to adults for oral administration.
For treatment of venous insufficiency and chronic hemorrhoids, it is recommended to take 2 tablets per day during meals: in the afternoon and in the evening. After 7 days of this method, you can take 2 pieces at a time a day during meals.
In acute hemorrhoids should take 6 tablets a day for 4 days, then - 4 tablets a day - 3 days. The medication should be taken with meals, previously divided into 2 - 3 times a day.
The treatment therapy period lasts 2-3 months.
Overdose and Adverse Reactions
No cases of an overdose with Avenue have been reported.
But if there is discomfort, there is a headache, nausea, you should rinse the stomach with plenty of water and drink activated charcoal.
The manifestation of the side effect of the drug may be:
- digestive system disorders ( gastrointestinal tract):
- symptoms of : nausea, vomiting, diarrhea, colitis, indigestion.
- special instructions : get rid of nausea and vomiting will help taking the tablets after a meal, since the food protects the mucosa of the digestive system from contacting the tablets directly. If the disorders of the gastrointestinal tract are associated with an irritating reaction of the drug, then after the end of its reception, they disappear.
Mild disorders of the nervous system:
- symptoms of : malaise, weakness of the body, headache, dizziness.
- special instructions : rest, bed rest, ventilation of the room, fresh air, drink strong hot tea.
Allergic reactions of the skin and subcutaneous tissues:
- symptoms of : severe skin itching, rash on various parts of the body, manifestation of urticaria, isolated edema of the facial part( lips, eyelids), Quincke's edema.
- special instructions : in case of an allergic reaction, it is necessary to stop urgently, take activated charcoal or any antihistamine, contact a specialist to find out the reasons.
Other data
No studies of interaction with other medicines have been conducted. But with all this, there is a huge experience of the post-registration 
using the diosmin that is contained in the pills of the Avenue. No interaction was reported with other drugs.
When taking a course of taking medications, all alcoholic beverages are forbidden to be consumed. However, the pills that contribute to the elimination of venous insufficiency do not have critical limitations in the use of alcohol.
The use of the drug does not affect the reaction rate and the management of vehicles or to work with other mechanisms.
Indications for Pregnant and Lactating
During pregnancy, the risk of developing varicose veins is very high. For expectant mothers, it is very problematic to treat enlarged veins and vascular ruptures.
Before starting taking Avenue tablets, pregnant women should consult a doctor.
Tablets do not affect embryonic development of the fetus, conducted studies did not show a teratogenic effect of the drug, with adverse reactions patients did not apply.
During breastfeeding, the use of tablets should be discontinued, as there is no evidence of their effect on breast milk.
Opinion of consumers
Tablets Avenue with seven-league steps are gaining popularity among people suffering from varicose veins, which is confirmed by numerous reviews.
A month ago I turned to the doctor with a problem - I had a heaviness in my legs, swelling, my muscles began to ache. After the examination in the hospital, the doctor said that everything was in order with the veins on his legs, but if I'm worried about such symptoms, I advised him to take a course of Avenue for prevention. A month after the beginning of the use of medicinal tablets, I felt a significant improvement in my state of health. I still accept them, every day I feel the changes and I feel better and better.
Catherine
A good, effective drug Avenue and inexpensive, in contrast to Venarus, from the reception of which also the stomach hurts. The medicine is well tolerated without damage to the stomach. It helps significantly, especially in the evenings, the legs stop hurting and whining. After applying the course, the veins decrease, recover, come to normal appearance. These pills I have been drinking for more than 2 years, although I've tried many others. I stopped on it and advise everyone!
Elena
I have known this drug for a long time - I have been taking them for several years in a row, two courses a year. One course lasts two months. Means for me a bit expensive, but I'm not worried about problems with my legs. With his help, the veins on my legs look great, and varicose veins do not progress. I am very pleased!
Inga
The course of treatment with medicines Avenue lasts from 2 to 6 months and is repeated to prevent and prevent further development a couple of times a year. The repetition period and the duration of the course depend on the degree of the disease. But I advise you to consult a doctor - phlebologist.
Alexander
What else can I use to treat veins:
Useful information in doctor's reviews
Avenue medication is prescribed for those who suffer from problems with the vessels of the hip and lower extremities. Potential clients I have are people with a disease of varicose veins, hemorrhoids and thrombophlebitis.
We recommend the drug to patients of any stage, because it is suitable for both prevention and treatment.
Therapist Anna Maksimovna
The Avenue tablets have proven themselves very well. Patients noted a marked improvement, a reduction in pain and edema on the legs, and a lack of strong adverse reactions. I advise the drug for patients with varicose veins, hemorrhoids and trophic ulcers.
Surgeon Ivan Petrovich
Conditions of purchase and storage
The drug is sold for 30 - 50 tablets in a package. The average price of Avenue tablets is from 370 to 780 rubles.
The drug should be stored in the original pack at a temperature of up to 25 degrees. Keep out of the reach of children.
Shelf life 2 years. At the end of the expiration date, which is indicated on the pack, is not suitable for use.
The drug is sold in pharmacies without a doctor's prescription.
Analogues of Russian origin
The drug is used as a venotonic and angioprotective agent, which causes an increase in venous tone and, as a consequence, a decrease in venous stretch and varicose veins. Pharmaceutical manufacturer - PJSC Farmak, Ukraine.
To date, there is a large number of analogs of this drug, both foreign and Russian. Preparations in which the ATX code coincides with the Avenue tablets and which contain additional substances hesperidin and diosmin of foreign origin:
- Anvenol - Czech Republic;
- Venorin - Spain;
- Venosmine - Ukraine;
- Dzhuantal - India;
- Diophlan - Ukraine;
- Nostalix - Greece;
- Venolan - Poland / Hungary;
- Troxsegel - Bulgaria;
- Troxerutin - Bulgaria.
The most common analogues of Avenue of Russian production are:
- Detraleks - representative office in Russia;
- Venarus;
- Venozol;
- Flebodia 600 is a representative office in Russia.