Use of Luxfen in the treatment of glaucoma

Have you or your family been diagnosed with open-angle glaucoma? What are the reasons for its appearance?

Than it threatens? And most importantly - how to cure the disease, preserving the vision?

Glaucoma is an eye disease caused by increased intraocular pressure( IOP).

Without timely treatment, there is a risk of damage to the optic nerve, resulting in narrowing the field of view and loss of visual acuity, which leads to irreversible blindness.

The disease is chronic, completely incurable, but in the early stages of treatment the development of pathology can be prevented and normal vision preserved.

The basis of the treatment is a means of lowering IOP, namely drops for the eyes. One of the recommended drugs for the treatment of this pathology is Luxphen .We describe in more detail its action and advantages.

Contents
    • 1. Application Guide
    • 2. Contra-indications and side effects
    • 3. Storage conditions
    • 4. Price
    • 5. Analogues
    • 6. Reviews
    • 7. Let's sum up
    • 8. Video in the topic
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Guide toThe use of

Luxfen is an eye drop used to lower intraocular pressure and is prescribed to treat open-angle glaucoma.

Composition, Form

The composition of the preparation is as follows:

The main active ingredient

Excipients

Brimonidine tartrate( 2 mg)

  • Benzalkonium chloride( antiviral);
  • water;
  • sodium chloride( solvent, replenishes the lack of liquid);
  • polyvinyl alcohol( polymer);
  • monohydrate of citric acid;
  • sodium citrate dihydrate( stabilizer);
  • hydrochloric acid;
  • sodium hydroxide( caustic soda).

Eye drops are available as a clear solution of a greenish-yellow hue in a vial( 5 ml), packed in a cardboard box with instruction manual.

Pharmacological action of

After instillation of a 0.2% solution twice a day for 10 days, its concentration in the blood plasma is extremely low( mean value 0.06 ng / ml).

Binding of brimonidine to proteins in the blood after local administration of drops is at the level of 29%.

After two weeks of instillation, the concentration of the active substance on the eyes can be 3-17 times higher than after a single use of Luxfen. In the absence of melanin accumulation is not observed.

The solution for a maximum of a couple of hours can reduce IOP by 10-12 units. Actions last for 12 hours. The drug is effective due to decreased fluid production in the eyes and increased outflow.

As a result, intraocular pressure decreases, not significantly affecting the cardiovascular and respiratory system.

The drug is metabolized in the liver. The active component with metabolic products by the kidneys is excreted.

Indications

These eye drops are intended for patients with open-angle glaucoma or susceptible to too high IOP( ophthalmic hypertension).

Thanks to its active ingredient, drops help the body to fight the following manifestations of glaucoma:

The drug can be used as an independent medication and in combination with other drugs of a similar action if monotherapy does not yield results.

But there are several nuances in the interaction of medication with other medicines:

  • when taking funds that affect metabolic processes, use drops with caution;
  • when using antidepressants of the central nervous system, remember that the action of Luxfen can enhance their effect;
  • with caution use drops with dysfunction of the liver and kidneys, coronary and cerebral insufficiency;
  • manufacturer warns to use drops with medications that lower blood pressure.

Carefully read the precautions for the use of drops:

  • If you wear contact lenses, remove them before applying drops to the eyes, as some components may cause irritation. You can insert the lenses back after 15 minutes;
  • because of the feeling of drowsiness and temporary loss of vision clearness, it is better to refuse to drive the machine and work with complex mechanisms until the visual acuity is fully restored;
  • with allergy to the solution, stop using it.

How to use

  1. Bury 1 drop of Luxfen in the conjunctival eye bag, slightly pulling down the lower eyelid, twice a day( every 12 hours).
  2. If you are not sure of the drop in the correct place in full, repeat the action.
  3. After the administration of each drop, close your eyes and press your inner corners of the eye with your finger - this will ensure the full flow of the solution into the eye tissues.
  4. If you need to drip other drops, do this after 15 minutes.after instillation of Luxfen.

The duration of the treatment will be determined by the doctor.

Contraindications and side effects of

  1. Individual intolerance of the active or auxiliary components of the drug.
  2. Age under 2 years old.
  3. Lactation period.
  4. Simultaneous treatment with tricyclic antidepressants or monoamine oxidase inhibitors.

If you do not have contraindications for taking this medication, you can start treatment.

Side effects of

On the part of the visual organs:

  • allergic reactions of the mucous membrane of the eyes or eyelids( irritation, itching, inflammation, burning, tearing, pain, swelling of the eyelids);
  • blurring of vision;
  • photophobia;
  • dry eyes;
  • conjunctivitis;
  • deterioration of vision clearness;
  • sensation in the eye of litter or foreign body;
  • is a chronic inflammation of the eyelid margins;
  • sometimes barley.

Cardio-vascular system:

  • cardiac arrhythmia, arrhythmia;
  • painful heart palpitations;
  • decreased heart rate, slowed heart rate;
  • sometimes a rise in pressure, less often - hypotension.

From the central nervous system:

  • headache and dizziness;
  • state of drowsiness;
  • rarely occur fainting.

From the gastrointestinal tract:

  • digestive disorders, nausea;
  • sensation of dry mouth.

On the part of the respiratory system:

  • cough and asthma;
  • inflammation of bronchial mucosa;
  • sometimes dryness in the nasopharynx.

General condition disorders:

  • fatigue, weakness;
  • skin rashes;
  • is sometimes depressed, sleep disturbance.

Almost all medications have side effects when taken in the maximum dosage or with individual intolerance of any components.

If they become more severe, stop the course and see a doctor for corrective treatment.

Usage during pregnancy and lactation

There are no data on the safety of the use of the active substance of the drug in pregnant and lactating women. When studying the effect of the active substance on animals, no abnormalities were found in the fetus.

But the risk can not be ruled out entirely. Most manufacturers indicate that the use of the drug during fetal gestation is allowed only in cases where the benefit to the mother is more risky for the fetus or the baby.

If you are prescribed a drug during lactation, stop breastfeeding for the duration of the course of admission.

Overdose

Happens very rarely.

If the drops accidentally enter orally, the body temperature or blood pressure may decrease, drowsiness and apnea may occur( respiratory arrest in sleep lasting about 10 seconds), slowing of the pulse. In this case, it is necessary to treat the symptoms and control the patency of the respiratory tract.

Storage conditions

Solution of drops is suitable for 2 years.

After opening, store medicine 28 days away from children at a temperature of no higher than 25 ° C, protect from direct sunlight. Do not use the medication after this time.

Price

Average price of Luxfen in Russia - 429,5 руб.

Average cost of drops in Ukraine - 194,5 grn.

Analogues

  • Alfagan P - eye drops with the content of active substance Brimonidine 1.5 mg( compare price 733 rubles, 226 UAH);
  • Xalacom is a drug with active ingredients: latanoprost 50 μg, timolol 6.83 mg( 766 rubles, 680 UAH);
  • Asopt - suspension, where the main active ingredient is Brinzolamide 10 mg( 878 rubles, 220 UAH);
  • Betoptik - solution of eye drops of 0.25% with the content of the active component of betaxolol hydrochloride 2.8 mg( 395 rubles., 108 UAH).

All these drugs effectively reduce IOP and are indicated for the treatment of open-angle glaucoma.

You need to know the enemy in person! These drugs will help you get rid of the following symptoms of glaucoma:

Reviews

Patients using Luxphene to lower the intraocular pressure, declare the presence of side effects specified in the instructions, but the discomfort goes through 5-10 days of application of drops, as the body gets used to the new drug.

There are complaints about the appearance of tearing, burning and sensation of rubbish in the eyes when applying eye drops Luxfen and Betoptik in the complex.

Some advise more to walk in the fresh air. If side effects occur, they often go away within 30 minutes, as the drug dissolves in the blood and is neutralized.

Practicing ophthalmologists report that taking Luxfen with other drugs effectively reduces IOP: a combination of brimonidine with latanoprost helps reduce the ophthalmotonus by an additional 4 mm Hg.art.the effect as a whole is 33-39% of the initial level.

If the drug does not give results or if severe side effects occur, laser or surgical treatment is prescribed.

If you or any of your friends have experience using drops of Luxphen as a monotherapy or in combination with other medicines, please leave your recommendation. Your feedback will be useful to visitors of the site.

Summing up

  1. Glaucoma is not a verdict. To maintain good vision is possible with the use of effective drugs, among which there are eye drops of Luxphen, containing brimonidine as the main active substance.
  2. Luxphen in a dosage of 1 drop twice a day is indicated with increased ophthalmotonus and open-angle glaucoma, however, before reading, you should carefully read the manual for use, as there are a number of side effects, contraindications and precautions.
  3. The average cost of this drug in Russian pharmacies is 430 rubles. In Ukraine, for a solution of drops, you need to pay about 195 UAH.There are several equally effective counterparts of different pricing policies.

Video on the topic

We recommend to see the following material about glaucoma:

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  • Mar 28, 2018
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