Escuzane is a medicament, the main component of which is escin, a substance derived from the fruits of horse chestnut.
The main task of the drug group to which this drug relates is vascular strengthening and improvement in the outflow of blood .
Thanks to the active ingredients, Escuzane is used as a remedy for circulatory disorders in the veins.
Contents
- Drug abuse
- Indications for use
- When should medicine not be taken
- How does the body act
- Instruction for use
- How to use
- Dosage
- Forms for the release of Escudane
- Drug in tablets
- Drops
- Ointment and gel Escuzan
- Overdose and additionalindications
- Side effects
- Special instructions
- Interactions with other drugs
- In pregnancy and lactation
- Aboutphysicians 'and patients' contacts
- doctors opinion What
- patients think Pros and cons of
- Release forms and prices
- Analogues of
- preparation
- escavitas Aescin
- Venoplant
- Venastat
- Eszin
Pharmacological action of drug
Eszin, according to medical reports, exerts a tonic effect on blood vessels, thereby strengthening them and preventing fragility, improves metabolism in tissues.
When investigating the effect of the drug, was noted to significantly reduce swelling, pain, itching, burning .The feeling of heaviness, fatigue and tension was reduced.
Pharmacokinetics characteristic of
The absorption and distribution of the drug is observed after 2.5 hours and is half the dose. Conjugation with blood proteins is 84%.
The withdrawal from the body occurs after 20 hours. It is excreted by the kidneys in the form of escin.
Indications for use
Guideline for use of the preparation Escuzan indicates a wide field of application of preparation:
- is prescribed for venous insufficiency and its complications;
- for varicose veins;
- for diseases associated with impaired blood flow( leakage, convulsions);
- with the appearance of heaviness in the legs, pains;
- in case of tissue nutrition disorders( trophic ulcers), in the prevention and treatment of bruises, with edema of the brain, with hemorrhoids.
When to not take medicine
The drug is contraindicated when:
- is not prescribed when an allergic reaction to escin is detected( rashes, itching, urticaria are possible);
- in the first trimester of pregnancy( no known effect of the drug on the fetus);
- in renal failure( escin is partially excreted from the body by the kidneys and can adversely affect their activity).
How it works on the body
When getting into the body, Escuzon affects the capillaries, removes effusions, normalizes the walls of blood vessels, improves blood flow, thereby reducing the risk of blood clots, increases their resistance to unfavorable conditions and toxic substances, eliminates brittleness.
Hyaluronic acid, having got into the body, gives the veins elasticity and attracts liquid, the composition of Escuzan prevents its destruction and allows to carry out its function further.
Instructions for use
Before using the Escouzin ointment or tablets, you should carefully read the instructions for use.
So, initially the surface of the skin needs to be washed thoroughly. It can also be used in conjunction with compression knitwear( elastic bandage), applying Escuzan under it.
The result of treatment depends on the regular application. The course of treatment can be about six months or more. The preparation is not applied to the damaged skin areas, an allergic reaction( burning, itching) can occur.
How to use
The Escuzan is applied by gentle circular motions, several times a day, to the pads of your fingers on the damaged areas of the skin.
Dosage of
The dosage depends on the illness and on its stage. As the disease progresses, the dose is increased. The administration of the drug and the change in its dosage are consistent with the attending physician.
Forms of release of Escuzane
The preparation of Escuzane is manufactured by in the form of tablets, tablets ( two types, tablets called Escuzan 20( coated) and long-acting tablets), drops, gels and ointments .
All depends on the amount in the form of escin, in a 5 mg tablet, in tablets coated with 20 mg capsules, in long-acting tablets 50 mg, in drops the presence of escin depends on the capacity of the bottle( 20 ml bottle contains 75.6 mg).
The action of the drug in all forms is the same for , since they all contain the same substance - escin. Tablets, dragees and a solution have a short-term effect, due to the fact that half of the received dose is excreted from the body in an hour.
Drug in tablets
Tablets and pills enter the body and blood through the intestines. Split with enzymes of the kidneys, along with bile enter the intestine and are excreted from the body by feces.
Assigned they with:
- edema of the legs( in particular the shin);
- the consequences of thrombophlebitis;
- pain in the legs;
- for varicose veins;
- in case of tissue nutrition disorder( trophic ulcers);
- with bruises, abrasions, sprains, tendon rupture;
- in the postoperative period, when there are pain, swelling;
- with hemorrhoids.
Have a number of contraindications. It is impossible to apply them in case of allergy to escin, susceptibility to the formation of blood clots, pregnant in the first semester, breastfeeding, children under 12, with kidney failure.
Treatment, these forms is about 2-3 months, but depending on the results of treatment and the severity of the disease course can last up to a year. When ingestion of these forms, there is an indication, to drink them with a copious amount of water.
They are taken before meals, and the measure of intake depends on the symptoms and severity of the disease, which ranges from 15 mg to 100 mg per day. They should be taken with caution with oral contraceptives, antibiotics, anticoagulant drugs.
Ingestion can occur side effects, such as nausea, heartburn, frustration.
There may be a rash on the body in the form of urticaria. Body temperature may rise. But all these phenomena occur rarely.
Drops
Drops Escuzane is a solution of yellow or reddish-brown color with a specific odor. Dark bottles of drops, closed with a stopper in the form of a dropper.
Escuzan in drops based on the instructions for use is prescribed for:
- venous insufficiency, blood flow disturbance;
- edema, cramps, leg pain;
- hemorrhoids.
It is not recommended to take if susceptibility to escin is detected, to children under 12 years of age, pregnant and lactating.
The preparation of this form is administered orally( through the mouth) or intravenously. The dose is given depending on the condition of the disease and on the necessary amount of escin to the patient.
Children prescribe the drug, according to the formula based on the body weight of the patient. For 1 kg of body weight - 200 mg per day .The number of receptions is determined by the attending physician. Overdose is not excluded, it is expressed by a disorder of the intestine, pains and spasms inside the abdomen.
Ointment and gel Escuzan
The properties of ointment and gel are very similar, the difference in the speed of penetration into the body and appearance.
The gel has a light structure( more often is used in conjunction with the compression therapy ), and the ointment is more viscous and greasy( is used as a compress ).
The use, contraindications and action of the ointment and gel Escuzan are the same.
Are prescribed with:
- edema, convulsions, sensation of heaviness in the legs;
- for varicose veins, with trophic ulcers;
- bruises, abrasions, bruises;
- for prophylaxis after vein operations.
Contraindication of is the presence of an allergy to escin.
The drug is applied to the skin with light circular motions from 1 to 3 times a day, and the result of treatment can be achieved from a month to six months, depending on the neglect of the disease.
To achieve a positive and quick result, doctors recommend combining gels and ointments with compression linen or bandages.
For prolonged use, hives, itching, and rashes may occur on the skin.
Overdose and additional indications
Overdose has its own characteristics depending on the form of the drug. In all cases, it is an allergic reaction to the constituents of the medicine.
Gels and ointments can be given to children from any age. Drops in the mouth and intravenously from 3 years. Tablets and pills from 12 years.
Side effects of
Side effects of from dragees, tablets, drops - nausea, vomiting, dizziness, from ointment and gel - rash, itching, urticaria on the skin.
Special instructions
Before starting the appointment, consult a doctor and check the kidneys.
Interactions with other medications
Use with caution the preparation with antibiotics and anticoagulant drugs.
In pregnancy and lactation
Beginning with the second one, you can use Escuzane inside( provided that the kidneys work normally).In case of acute need, you can use( under the supervision of a doctor) ointment and gel. In the period of feeding is not recommended.
No data on the effect of the drug on the fetus.
Reviews of doctors and patients
Opinion of doctors
To date, most specialists agree on positive feedback from about drops and tablets of Escuzan.
"This is a modern tool. Eskuzan is a phyto-drug because it is made from vegetable raw materials. Very actively affects the entire body of the patient( hormonal system, metabolic processes, etc.).Side effects, although described in the instructions of the drug, were extremely rare, but its effect does not make you wait long. "
What patients think
Patients' opinions about Escuzane diverge, are found both positive and negative. Negative responses are formed by patients who discontinued their treatment or used an agent to treat diseases of non-infectious vessels.
Pros and Cons of
After examining the opinions of doctors and feedback from patients, we come to the conclusion that is the only minus of Escudane - long-term use and not an opportunity to use during pregnancy.
Forms and prices
Today all the forms of the release of Eskusan can be purchased in pharmacies without a doctor's prescription. The average cost is shown, which can vary depending on the surcharge and the location of the pharmacy:
- tablets Escuzan - the price is 120 rubles;
- drops Escuzan - the price of 105 rubles;
- ointment and gel - the price of 200 rubles.
Analogues of the preparation
Escuzane has many drugs - analogs, which are somewhat inferior, and in some ways superior to the drug.
Escuditis
To the analogues of Escuzan is the preparation with the name Escuvite, the main component of which is escin.
The drug has the same effects on the walls of the vessels, as does Escuzan.
Assign it to with:
- varicose veins;
- venous insufficiency;
- edema, heaviness in the legs;
- injuries;
- trophic ulcers;
- for prophylaxis after surgery and with complications caused by them.
It is available in the form of tablets and drops.
Duration of administration varies from 3 months to 6 months.
Contraindications include : allergic reaction to escin, pregnancy of I and II semesters, lactation period, not recommended for children under 12 years.
Allergic reactions( rash, itching, urticaria) are possible. If changes in digestion are observed, it is recommended to use Escouvit during meals.
Aescin
It contains thiamine, in contrast to Eskusan, but the action and designation of is identical.
Produced in the form of tablets( after meals, drink plenty of water) and gels.
The average duration of Aescin treatment is from 2 months.
Contraindications: pregnancy, feeding period, children under 18 years old, allergic reaction to the components of the drug. The gel should not be applied to open wounds and mucous membranes.
When using tablets, may have side effects: nausea, vomiting, tachycardia, pruritus, urticaria, in high doses - thrombosis. When studying the gel, no adverse reactions were detected. In some cases there was itching and urticaria, which passed themselves after the treatment.
The
Venoplant The main component is escin.
Assignments and indications is akin to Escuzan.
Produced in the form of tablets( before meals, drink plenty of fluids).It is prescribed 2 times a day for one tablet. It is transferred easily. In some cases, itching and nausea.
Interactions with other drugs have not been studied, so you should consult your doctor before use.
Venastat
Venotonizing, the main component is escin. Available in the form of gel, cream for external use, and tablets.
Indications for use and mechanism of action as in Escuzan.
Side effects: nausea, vomiting, urticaria, pruritus occur very rarely. It is prescribed for children( of any age), pregnant. It is necessary to check the activity of the kidneys during the use of the drug. Enhances the effect of anticoagulants.
Eszin
Produced in the form of tablets and gel. Tablets( after meals, drink plenty of water).
Assigned with:
- varicose veins;
- hematoma;
- edema;
- hemorrhoids;
- after operations on veins.
Contraindications: I semester of pregnancy, breast-feeding, kidney failure. Restrictions apply to people prone to thrombosis, sometimes there is a violation of kidneys. Possible side effects: urticaria, nausea, itching.
In this case, the drug can interact with other medicines, increasing or decreasing their therapeutic effect, so do not use it without consulting a doctor.