What you need to know about the gel and capsules Troxerutin: instructions for use, reviews and the price of the drug in pharmacies

Troxerutin refers to medicines of a group of angioprotectants and microcirculation correctors.

The substance of troxerutin is a derivative of routine, related to the semi-synthetic type.

In the normal state, it is a yellow powdery powder that dissolves easily in water, propylene glycol, glycerin. Virtually unaffected by dissolution in ether, chloroform, cold ethanol, benzene.

Pharmacology drug

Troxerutin differs pronounced activity venotonicheskogo, membrane stabilizing, anti-inflammatory and kapilyaroprotektornogo types.

P-vitamin activity of the drug promotes activation of oxidation-reduction processes, stabilizes the level of hyaluronic acid of cell membranes, reducing the overall background of their permeability.

The activity of the drug promotes the normalization of the permeability of the capillary walls, increasing the overall tone.

Also, the action of troxerutin is aimed at increasing the level of vascular wall density, reducing the exudation of the liquid segment of plasma and diapedesis of blood cells.

There is a decrease in exudative inflammatory processes in the area of ​​the vascular walls, limiting the adhesion of the wall to the surface of platelets. The drug is applicable both at the beginning of treatment and at the late stages of the course of the disease.

It is possible for to use troxerutin as a component of the complex therapy of .

Pharmacokinetics of the drug

For the administration of the drug inside, the substance is absorbed from the gastrointestinal tract.

The maximum concentration level of the substance in the plasma is fixed approximately two hours after ingestion.

The substance is metabolized in the liver. It is excreted from the body partially in an unchanged state, along with bile and urine.

Indications for use

The drug is prescribed if the patient has such types of diseases:

• venous insufficiency of a chronic nature;
• trophic disorders that occur during venous insufficiency of a chronic type( there are trophic ulcers, dermatitis);
• of vein dilatation in varicose veins;
• postthrombotic syndrome;
• edema and hematomas of postthrombotic nature;
• retinopathy, diabetic angiopathy;
• hemorrhoids.

Contraindications to the use of

When not allowed to use preparation:

1. The level of sensitivity to the components of the substance is increased.
2. The drug is contraindicated as a treatment for people with edema of the lower limbs, formed as a result of impaired functioning of the kidneys, heart and / or liver. In the situations described above, treatment with troxerutin is not effective.
3. Troxerutin capsules are not prescribed as a therapy for patients with lactose deficiency, galactosemia and malabsorption of glucose-galactose.
4. The substance is prohibited for use in patients aged less than 15 years due to the lack of informative data on the efficacy and safety level of therapy in the age category described above.
5. Receiving the substance for a long time is very carefully appointed to people who have been found to have impaired renal function.
6. The substance is not taken with gastritis in chronic form( in the phases of exacerbation of the disease).
7. In the case of stomach ulcers and / or in the area of ​​the duodenum.

Mechanism of action of the preparation

Advantageously, works on venous vessels, strengthening the venous walls, reducing the level of their permeability.

During the application of the drug, the level of elasticity and tone of the venous valves increases. Troxerutin promotes the inhibition of inflammatory processes and the development of thrombotic formations in the veins.

Forms of preparation

1. The gel for the local( external) application is produced in an aluminum tube with a capacity of 35 g. The aluminum tube is transported and distributed in a cardboard package.
2. Capsules for internal administration. The cell contour blister made of PVC / A1 contains ten capsules. In a cardboard box, blisters are three in number. Capsules in packages are issued on 300 mg. Each carton pack contains instructions for use.

How and when the drug is used

It can also be prescribed to patients with painful symptoms that are traumatic ( as an example, sprains, dislocations, contusions, tonic muscle cramps).

Applicable in as a component of the comprehensive hemorrhoid treatment i. The drug is applied orally( capsules) and externally( gel, ointment).Instructions for the use of capsules, gels and ointments of Troxerutin are set out below, among the highlights, should be remembered:

Use of capsules

The capsule is taken as a whole, without chewing and / or pre-grinding. Take the capsule with a moderate amount of liquid. It is recommended to use capsules during food intake.

The duration of therapy is determined by the physician. Most often, adult patients are assigned one capsule two to three times a day until the symptoms disappear.

The drug is then used as a prophylactic agent with supporting functions( one capsule once a day).The total duration of therapy can vary from 5 to 7 weeks.

Gel

It is recommended to apply the substance on the skin in the area of ​​affected areas with a thin even layer.

With gentle massage movements, the gel is rubbed into the skin. The drug is prohibited from applying to the inflamed areas of the skin and mucous membranes. Do not get the gel into the eyes. After applying the gel, you should wash your hands.

The duration of therapy is determined by the attending physician. Adult patients of are prescribed rubbing with gel two to three times per day. Combined therapy is also acceptable.

Dosage of the drug

Internally during meals, the drug is taken at 0.3-0.9 g during active therapy. As maintenance therapy, taking the drug is internally reduced to 0.3 g within 24 hours.

For external( local) application of the gel, 2% of the substance is used, evenly applied in a thin layer to the area with severe symptoms.

Overdose

At the moment there is no evidence of an overdose of the drug.

In case the preparation in the form of capsules was taken at a significantly higher dosage, or an accidental ingestion of the drug in the form of a gel, it is recommended to rinse the stomach and then take enterosorbents.

Possible manifestation of such symptoms, as:

• nausea;
• headaches.

Side effects of

Similar processes after taking the substance may manifest as symptoms:

• headaches;
• irritative processes in the gastrointestinal tract;
• reactions of an allergic nature( skin rashes, itching are possible).

Special instructions

As a result of taking the drug, no negative mental and / or motor reactions occur. The preparation does not interfere with driving and / or mechanical work.

In case the drug is used in the treatment of superficial thrombophlebitis or deep vein thrombosis, combining the use of agents with anti-inflammatory and antithrombotic properties is not excluded.

Interaction with other drugs

With combined therapy, Troxerutin enhances the action of ascorbic acid on the level of permeability and the integrity of the structure of the vessel walls.

Usage in pregnancy

Troxerutin in capsule form for internal use is not recommended for use in the first trimester of pregnancy.

In the future, the drug is prescribed by the doctor, taking into account the excess of the expected benefit from therapy in comparison with the possible risk to the fetus.

A substance in the form of a gel can be used during pregnancy. Also the use of the drug in the form of a gel does not require interrupting the treatment of for the lactation period, since the substance has a low level of systemic absorption.

At the same time during the breastfeeding , the use of capsules is undesirable.

Reviews of patients and doctors

The drug is widely used by modern consumers to relieve swelling of the lower extremities. The most positive reviews of patients about Troxerutin gel, a little worse about Troxerutin in capsules

Such statements are widely supported not only because of the effectiveness of the drug, but also at a very reasonable cost.

The cost of the preparation

The price for Troxerutin varies depending on the form of release and the size of the package.

1. Troxerutin in capsules 300mg .The cost of the drug for internal use varies from 160 to 220 rubles.
2. Preparation in the form of 2% gel 40g .The cost of the drug is from 22 to 35 rubles.

How to replace the drug

There is a large number of analogues of Troxerutin. Let's dwell on the main ones.

Antistax

is used by as a preventive and symptomatic therapy for chronic venous insufficiency. In the process of taking the drug, there is a reduction in the level of permeability of the capillary walls, angioprotective effect.

Antistax is based on the extract of red grape leaves with the addition of active flavonoids( quercetin-glucuronide, isokvertsetin).

Antistax is available in capsules of 20 pcs.in a cardboard package of 180 mg.

The cost of the drug varies from 540 to 1300 rubles.

VENOSMIL

The chemical structure of the hydrosmin active substance belongs to the group of flavonoids. The substance affects the level of reduction in permeability of capillary walls caused by the use of substances such as histamine, bradykinin and others.

Stabilizes and improves the properties of erythrocytes of a hemorheological nature. The preparation reduces the level of fragility of capillaries , which was caused by improper diet, reduces the level of viscosity of the blood.

Venosil improves the clinical symptoms of venous insufficiency of the peripheral type( eg, swelling, pain impulses, sensation of gravity during movement and / or breathing).

The drug is prescribed to patients for a short-term relief of the symptoms of the disease and is taken no more than three months. Produced in the form of capsules in blisters for 6-9 pieces in a cardboard box.

The cost of the drug is from 959 rubles.

Venoruton

The action of the drug Venoruton has a venotonic and angioprotective effect.

The drug is available in the form of capsules for internal administration and as a gel for external use. The substance helps to strengthen the vascular walls, normalizes the level of their permeability.

The use of prevents intercellular cracks and a sharp increase in the level of hydroconductivity.

The cost of the drug in capsules for internal reception is the amount from 590 to 700 rubles .Venoruton gel can be purchased 270-330 rubles.

Troxevasin gel

The preparation is used by for the symptomatic treatment of venous insufficiency, superficial thrombophlebitis, pre-varicose and varicose symptoms, phlebitis and as part of a comprehensive hemorrhoids treatment.

Eliminates the symptoms of - swelling, pain impulses, muscle cramps( convulsive heaviness in the calf muscles).The drug is available in the form of 2% gel for 40 / 100g in aluminum tubes and carton.

The cost of the gel varies from 140 to 470 rubles.

Ascorutin

is prescribed to patients as part of a set of pathological measures, accompanied by an increased level of vascular wall permeability.

The substance can also be used as a prophylactic for colds, as it helps to reduce the symptoms - headaches, painful spasms.

The drug is vitamin and is available in the form of tablets of 50 pieces per pack.

The cost of askorutin is from 25 to 35 rubles.

Indovazin gel

The combined preparation has anti-inflammatory, anti-edematous, aneliziruyuschim action and is intended for external use. It helps to reduce swelling, pain syndromes, reduce the level of permeability and fragility of capillaries.

Has a strengthening effect, stabilizing the tone of the vascular walls.

Promotes improvement of microcirculation processes. The preparation is made in the form of a gel for external use of 45 g in an aluminum tube and carton.

Approximate cost of the drug - 180 rubles.

GYNKORE FORT

The preparation is manufactured in the form of capsules for internal use.

Has features such as: reduction of pain syndrome, increased level of stability of capillary walls, reduced permeability of vessel walls, restoration and stabilization of microcirculation and venous blood flow.

Combined drug is prescribed for patients with venous circulation disorders. The estimated cost of the drug is 440 rubles.