When a woman has problems with conception, treatment raises many questions and often scares the terminology. What is a hCG prick, in which cases it is used, how effective it is, what contraindications it has - let's look at it together.
Contents of
- HCG prick - instruction
- HCG injection: for what purpose and when?
- A hCG prick for ovulation
- After how much after an injection of hCG ovulation occurs
- After how much after an injection of hCG do the test
- Injections of hCG during pregnancy
- Video: Ovulation stimulation
Human chorionic gonadotropin( hCG) - this term designates a hormone that is produced in the body after fertilizationovum and is responsible for the preservation and development of the fetus during pregnancy. It is the determination of the level of this hormone that underlies the pregnancy test.
HCG injection - instruction
- Hormonal preparation of hCG is synthesized from the urine of pregnant women or genetically modified microbes with a recombinant DNA.Pharmacological action is based on stimulation of the ovulatory cycle, spermatogenesis and production of sex hormones
- in the ovaries. The drugs based on hCG are effective in the deficiency of the yellow body, ovarian dysfunction, infertility caused by the absence of ovulation, the threat of abortion, the risk of premature birth. These hormonal drugs can also be prescribed with assisted reproductive techniques( in vitro fertilization).
- Gonadotropin chorionic is available as a solution for intramuscular injection or lyophilizate( a component for the preparation of a solution).In the case of stimulation of ovulation, injections are made to the abdomen with a syringe with a short( insulin) needle. This method is more effective and painless
- The dosage of the drug, as well as recommendations for its use, are prescribed by the attending physician on the basis of multiple studies. The exact dose of the drug should be calculated strictly individually, based on the level of hormones, the size of the follicles, the thickness of the layer of the endometrium of the uterus and data from other analyzes of
- . As preparations for injections, Menogon, Pregnil, Humegon, Profazi, Novarel, Ovidrel and others are used. Their action is aimed at restoringfunctions of ovulation and stimulation of hormonal activity caused by an increase in the blood level of hCG
. In general, the following doses of the drug are used:
- when ovulatingOne-time 5000-10000 ME
- is assigned at the risk of miscarriage, as well as the threat of abortion - no later than the 8th week of gestation for the first time 10,000 ME, then 2 times a week until the 14th week inclusive - 5000 ME
- In processartificial insemination after stimulation of the development of follicles is prescribed once 10,000 ME
The injection of hCG has a number of contraindications that need to be addressed:
- poor-quality ovarian tumor formation
- early onset of menopause
- period l
- thrombophlebitis or a predisposition to this disease
- established obstruction of the fallopian tubes
- chronic inflammatory diseases of the adrenal glands
- individual sensitivity to the components( allergy)
If the procedure is violated or the drug overdose, there may be side effects in the form of acne, polycystosis, ascites, thromboembolism due tohyperstimulation of the ovaries.
HCG injection: for what do they do and when?
The injection of hCG is used as a medicament for the prevention and treatment of female infertility, as well as the preservation of the fetus during pregnancy. Injections are made:
- to stimulate the egg and reduce the risk of cyst formation that occurs when the follicle does not burst but shrinks in size
- to preserve the vitality of the yellow body during early pregnancy
- to maintain the function of forming and developing the placenta
- at risk of miscarriage - especially if suchpathologies have already been repeatedly
- in the case of artificial insemination for the effect of "superovulation"
The injection of hCG for ovulation
The most common hCG injection is used in the absenceand ovulation, i.e.violation of the function of maturation of the ovum, capable of fertilization. This condition can be due to various reasons:
- polycystic ovary
- tumor formation
- increased physical activity and fatigue
- stress states
- taking certain medications
During the diagnosis of the violation of ovulatory function, a woman needs to pass tests for the level of hormones, regularly record basal temperature, undergo ultrasoundstudy of pelvic organs.
- Such examinations should determine the need to stimulate ovulation by the injection of hCG.In some cases, the normalization of the level of thyroid hormones, testosterone and prolactin can naturally restore the ovulation cycle of
- . To confirm the absence of ovulation, a permanent ultrasound-control for the development and growth of follicles is assigned. The first study is carried out 8-10 days after the last menstrual period, then repeats with an interval of 2 to 3 days before the start of the next
. In the process of investigation, it can be established:
- Complete absence of ovulatory function due to malfunctionovaries - the maturation of follicles does not occur
- The main follicle ripens but does not develop to the required size
- The follicle develops normally, but follicular opening does not occursaddle and release of the egg
If it is found during the observations that the follicle does not burst, a hCG prick can be assigned to resume ovulation. After 24-36 hours after injection, an additional ultrasound is assigned to confirm successful stimulation.
After how much after the hCG prick, ovulation occurs
- If the problem is diagnosed, infertility treatment should be carried out under constant supervision. The first injection is given on the 2nd day of the cycle for 10 days.
- The entire process of maturation of the follicles and their growth is controlled by ultrasound. At a size of follicles of 20-25 mm stimulation of their opening occurs, for this purpose injection of hCG in the required dosage of
- is introduced. The increase in the level of the hormone occurs the same within the first 24 hours after the injection. Therefore, positive tests for ovulation during the first 3 days can not reliably testify to its onset
- Usually after the injection of hCG ovulation occurs in the period from 24 to 36 hours. In some cases, ovulation may not occur, or may occur much later. The onset of ovulation can be established with the help of ultrasound
- After confirmation of ovulation, usually prescribed injections of hormones of utrozhestan and progesterone to support the function of the ovaries
After how much after an injection of hCG do the test
- It is recommended to carry out the test for ovulation after 3 days after the procedure. The growth of the hormones level after the onset of ovulation occurs gradually and doubles every 3 days.
- Active growth is noted in the first trimester of gestation, as the body of a woman under the influence of the injected drug begins to actively develop hormones that promote conception - estrogen and progesterone
- Recommendations on the number and desired time of sex inthe period of stimulation is done by the attending physician taking into account the examination and the results of the spermogram of the man. After the main injection, you can start the next day with the necessary break before and some time after the formation of the yellow body - the actual onset of ovulation
Pricked hCG during pregnancy
Hormonal injections to pregnant women are prescribed in case of a diagnosis of a sharp drop in the content of chorionic gonadotropin in the blood. Before the appointment of hormone therapy, an additional examination is performed on the level of the hormone.
If the deviation from the norm values is significant and make up to 20% in the lower side, hCG injections are mandatory.
A decrease in hormone levels can signal the development of the following pregnancy pathologies:
- suspicion of ectopic pregnancy
- frozen pregnancy
- impaired functioning of the placenta
- threat of interruption
The presence of a high level of hCG hormone in the absence of pregnancy canis an indicator of the development of a cancerous tumor. Until now, it has not been established whether the hormone production is a consequence or cause of cancer, but since 2011, non-lecentered homeopathic and food products, the content of hCG, which have been advertised as ancillary drugs for the treatment of infertility, are banned for sale.