What is the reason for Quincke's edema and what to do for his treatment?

Quincke Edema is one of the most powerful types of edema known to medicine. The disease can be limited or diffuse. It develops under the skin, in fatty tissue and mucous membranes. Quincke's edema can be affected both in adulthood and in childhood, but most often it affects young people, children and the elderly are less likely to experience this disease.

  • Causes of
  • Symptoms of
  • First aid
  • Treatment of
  • In adults
  • In children
  • How to avoid

Causes of

Reasons for swelling of Quincke according to statistics consist in a sharp and aggressive allergic reaction to contact with the allergen.

Of the causes that cause this disease, allocate:

  1. The impact of allergens on the body. Most often, the cause of an allergic reaction is eating fish, citrus, chocolate, nuts, preservatives and colorants, contacting pollen with plants, fluff, feathers of birds or animal hair. In some cases, Quincke's edema occurs after insect bites, such as bees, ants, mosquitoes or wasps.

  2. Consequence of a lambliasis, hepatitis or helminthic infection that has entered the body.
  3. The presence of diseases associated with imbalance in the endocrine system, especially the thyroid gland.
  4. The presence of tumors or blood disease in the body.
  5. Exposure to chemicals, possibly some medications or physical factors, such as high blood pressure or temperature, as well as vibration.
  6. Allergic reaction to drugs, in most cases it provokes analgesics and sulfonamide preparations, antibiotics from a number of penicillin, in some cases cephalosporin.
  7. Congenital disorders, which consist in a lack of enzymatic composition in the body responsible for the disintegration of substances that provoke swelling of the tissues.
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Symptoms of

The disease is characterized by a sudden appearance and rapid development. Clinical symptoms of Quincke's edema are typical, and in a few minutes, in rare cases, several hours, different parts of the body, as well as mucous membranes are affected and become swollen. The disease can be manifested:

  • on the lips;
  • on the eyelids;
  • in the oral cavity( tongue, soft palate, amygdala);
  • in the respiratory tract;
  • in the gastrointestinal tract;
  • in the genitourinary area.

The manifestation of the disease is such that in some cases it is not possible to notice how the Quincke's swelling begins. Painful sensations during the disease is not observed, basically there is only a sense of overstrain in the tissue structures. If you lightly press on the swollen patch, the pits from the palpation are not observed. Also, there is no pain syndrome.

One of the most frequent manifestations of the disease is the face and throat. Symptoms of the edema of the Quincke of the larynx are the same as those of other organs, but when they appear, the consequences that lead to asphyxia, cyanosis of the tongue may begin.

Localization of symptoms in the throat is very dangerous, if it spreads, it can further damage the brain cells and lead to irreversible neurologic changes, and sometimes to death.

Regardless of the causes of Quincke's edema in adults, the duration of symptoms persists for several hours, in some cases of the day, after which they disappear. However, having retreated, the disease may appear again soon. Presence of symptoms in children is observed within only a few hours, but irrespective of this, first aid should be provided urgently.

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First aid

After first aid has been given to a patient with Quincke's edema, it is possible to significantly alleviate his condition and wait patiently for the doctors. It consists in the following actions:

  1. The patient should take a comfortable position and calm down as much as possible.
  2. At the same time, the allergen that triggered the reaction should be detected as quickly as possible and isolated.
  3. The patient is recommended to take the drug with antihistamine action, for this you can use Fenkarol, Diazolinum, Dimedrol. It is best in this case to use injections to exclude the possibility of developing edema of the gastrointestinal tract, because in this case the absorption of substances in the stomach will be disrupted.
  4. Then the victim should drink the maximum possible amount of soda solution, which is prepared from 1 gram of soda, diluted in a liter of water. Replace the soda solution with Borjomi water.
  5. To accelerate the absorption process in the body, the patient should take activated charcoal.
  6. Apply cold compress or ice to the site of edema.
  7. Provide the patient with free access to fresh airflow and remove all objects and clothing items that can cause difficulty breathing.
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Treatment of

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In adults

After the symptoms of Quincke's edema appear, adult treatment begins by identifying the true cause that provokes the disease. Based on this factor, the treatment is as follows:

  1. If the edema is caused by an acute allergic reaction, the doctor prescribes a suitable course of antihistamines. It can be drugs from the first, second or third generation. Preparations of the first generation affect the H1 receptors of histamine. The second generation of drugs works by blocking the histamine receptors and stabilizing the cells responsible for transporting histamine in the blood, and also relieves spasms in the airways. Preparations of the third generation carry out blocking of histamine receptors, without affecting the central nervous system.
  2. If the cause of edema are various infections, then, in addition to using drugs that suppress the edema of tissues, the treatment of pathology that provoked this reaction is carried out.
  3. Colchicine, sulfasalazine is prescribed in the event that the connective tissue that caused the edema is broken.
  4. If the disease is hereditary, the treatment consists in the gradual replacement of C1 inhibitors and bringing their quantity to the required level in the body.
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In children

In a child, treatment also consists of taking antihistamines, for example Ketotifen, Clemastin, Loratadine, Chloropyramine. Together with such drugs prescribe corticosteroids( Prednisolone, Hydrocortisone), as well as drugs with a diuretic effect, for example, Furosemide. Asocutine is used to make the vessels more dense.

Of the activities that are used for treatment in childhood, allocate:

  • nebulizer therapy with adrenomimetics( inhalation with potent anti-asthmatic drugs);
  • course of corticosteroids;
  • oxygen therapy;
  • hemosorption( removal of various toxic products from the blood).

If Quincke's edema in children develops in the larynx, then use urgent intubation or tracheostomy to allow the baby to breathe as soon as possible until the swelling has subsided. If the cause of edema in heredity, then the body is injected with plasma containing the inhibitor C1 esterase and protease.

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How to avoid

You can avoid this disease only by identifying allergens and avoiding contact with them. It is necessary to go to the reception to an allergist and hand over all the necessary tests and tests to identify such substances.

It is also very important to know the list of medications that can provoke an allergic reaction. In the case of an innate cause of the disease, healing should be started as soon as possible in order to avoid negative and irreversible consequences as much as possible.

Those who are accustomed to treating diseases independently, especially using traditional medicine recipes, it is worth remembering that if there was a symptomatology of Quincke's edema, treatment with folk remedies is unacceptable. This is due to the specificity of the disease, which appears due to unpredictable allergic reactions. The use of recipes of traditional medicine can aggravate the situation.

  • May 08, 2018
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