Actovegin belongs to the group of antihypoxants - a means that activate the cellular metabolism( metabolism) due to the effective utilization of circulating oxygen in the body. It increases resistance to hypoxia( oxygen starvation) and accelerates the regeneration of tissues. Possessing a wide range of effects, the drug is very popular, but its high enough price forces many people to look for cheaper analogs.
- during pregnancy
- For the child
- Algofin Forte
- Diosmin( Vazoket, Diovenor, Phlebodia 600 Flebofa)
- Dipyridamole( Chimes Parsedil)
- Meksidol( Meksiprim, Neurox)
- Trimetazidine( Deprenorm, Preductal, Trimectal)
The drug contains deproteinized( protein-free) extract( haemoderivat) from calves' blood as an active ingredient.
Form release: tablets( pills);solution for injections in ampoules;solution for infusions( droppers);gel 20%, cream 5%, ointment 5% for external use;eye gel.
The use of different forms of the drug and the duration of the course of treatment depend on the symptoms and severity of the disease. The instructions for use contain general recommendations, but each case requires agreement with the doctor.
Indications for use:
- cerebral circulatory insufficiency, including ischemic stroke, cerebrovascular disease, dementia( senile dementia);
- craniocerebral trauma;
- diabetic polyneuropathy;
- peripheral circulatory disorders( arterial, venous);
- angiopathy( impaired vascular tone);
- trophic disorders( deterioration of skin nutrition) with varicose veins;
- ulcers of different origin;Pressure sores;
- open wounds;
- thermal and chemical burns;
- prevention and treatment of radiation injuries;
- damage the cornea and sclera of the eyes( burns, ulcers, keratitis).
Among the side effects are allergic manifestations - redness, itching or rashes on the skin, weakness, dizziness, headache, fever, fluctuations in blood pressure.
Intrauterine infections and various diseases during child bearing can lead to placental insufficiency, when there is a threat of hypoxia or fetal hypotrophy( retardation).In such cases, prescribe Actovegin - it is included in the metabolic processes and participates in the regulation of energy supply: normalizes the uteroplacental blood circulation and gas exchange between the mother and the fetus, improves the functions of the placenta.
The drug or its analogs can prevent detachment of the amniotic egg, miscarriage, development of varicose veins and hemorrhagic nodules. They are also recommended for pregnant women suffering from diabetes mellitus.
For the child
The main reason for the prescription of the drug and its analogues to newborns and infants is chronic fetal hypoxia, as well as acute hypoxia( for example, cord embossing or prolonged labor), brain trauma. In such cases, the greatest efficacy is achieved with the use of Actovegin in injections.
Analogsto table of contents ^
Validsubstances - derivatives of chlorophyll, carotenoids, salts of fatty acids, film-forming agents. The form of release - ointment.
The drug promotes wound healing and is used for purulent-inflammatory, radiation and trophic lesions of the skin and soft tissues.
Algofin can be applied a thin layer on the cleaned surface of the wound, do with it applications, use with cotton swabs to fill the purulent cavities. The frequency of application depends on the nature of the lesion and varies from 2 times a day to 2 times a week.
Side effects: burning sensation, in some cases, pre-treatment with a local anesthetic is desirable.
Diosmin( Vasoket, Diovenor, Flebodia 600, Flebofa)
The active ingredient is diosmin. The form of release - tablets.
The angioprotective agent has venotonic activity. It is indicated for varicose veins, chronic lymphovenous insufficiency of the lower extremities, microcirculation disorders, hemorrhoids.
Take 1-3 tablets( 600-1800 milligrams) per day, the course of treatment can be from 7 days to 2 months.
Side effects: nausea, heartburn, abdominal pain, headaches, allergic skin reactions.
Dipyridamole( Kurantil, Parsedil)
The active ingredient is dipyridamole. The form of release - tablets.
Is an anticoagulant( dilutes blood).Effective in the treatment and prevention of impairment of cerebral circulation, coronary heart disease, arterial and venous thrombosis and their complications, microcirculatory disorders. It is also used to prevent placental insufficiency in a complicated pregnancy, but due to immunomodulating properties( the ability to stimulate interferon production) fights against influenza and ARVI.
The dosage of the drug and the duration of administration depend on the severity of the disease, and can range from 25 to 600 milligrams per day. Side effects: nausea, vomiting, diarrhea, headache or muscle pain, weakness, dizziness, palpitations, skin allergic manifestations.
The active ingredient is an extract of protein fractions obtained from the bark of the brain of cattle and swine. Form release - lyophilizate( powder) to prepare a solution for intramuscular injection.
Refers to nootropic drugs, effective for traumatic brain injuries, cerebral circulation disorders, encephalopathies, memory and thinking disorders, psychomotor and speech development delay in children, cerebral palsy.
The course of treatment consists of single injections for 10 days with the possibility of recurrence in 3-6 months: adults and children with a body weight of more than 20 kilograms are administered 10 milligram of substance, young children are given a dose of 0.5 milligrams per kilogram of weight.
Side effects: local allergic reactions( redness and itching of the skin).
Mexidol( Mexiprim, Neurox)
The active ingredient is ethylmethylhydroxypyridine succinate. The form of release - a tablet, a solution for injections. The toothpaste Mexidol is also produced.
Antioxidant of a new generation, used for circulatory disorders and atherosclerosis of cerebral vessels, vegetative-vascular dystonia, intoxication with neuroleptics, anxiety with neuroses, acute purulent-inflammatory processes of the peritoneum.
Take 1-2 tablets 2-3 times a day, but not more than 6 tablets( 600 milligrams) per day. In the form of injections the drug is injected or drip, the dosage depends on the nature of the disease, but does not exceed 1200 milligrams of substance per day.
Side effects: nausea, dryness of the oral mucosa, drowsiness, allergic manifestations.
Is the only drug-analogue of Actovegin for the active substance - deproteinized dialysate from the blood of dairy calves.
Form release and dosage: dragee - take 100 milligrams 3 times a day;solution for injection - it is desirable to dilute with saline in a proportion of 1: 1 and injected intravenously at 10-20 milliliters daily or several times a week;infusion solution - inject 250-500 milliliters of drip daily or several times a week;gel( jelly) and ointment for external use - apply a thin layer on the affected skin 1-2 times a day;dental adhesive paste - apply a thin layer on the oral mucosa 3-5 times a day;eye drops - instill 1 drop 3-4 times a day in a conjunctival sac.
Indications for use are the same as for the drug Actovegin.
Side effects: allergic reactions.
Trimetazidine( Depenorm, Preductal, Trimectal)
The active ingredient is trimetazidine hydrochloride. The form of release - tablets, capsules.
The drug reduces hypoxia of tissues, protects blood vessels and heart muscle, positively affects the cerebral circulation and vestibular apparatus, in the vascular pathology of the eye restores the functional activity of the retina.
Take 1 tablet( 20 milligrams) 2-3 times a day.
Side effects: dizziness, headache, sweating, nausea, abdominal pain, vomiting, diarrhea, skin rashes.
The active substance is a complex of peptides and amino acids from the pig's brain. Form release - a solution in ampoules for injection.
Psychoanaleptic, is used for violations of the central nervous system, worsening cerebral circulation, dementia, cognitive disorders( memory and thinking disorders), mental retardation in children.
The course of treatment lasts 10-20 days, the dosage depends on the severity and nature of the disease, and ranges from 5 to 50 milliliters of substance 1 time per day. The dose for children is 0.1-0.2 milliliters per kilogram of body weight.
Side effects: fever, sweating, dizziness, headache, agitation, insomnia, nausea, vomiting, diarrhea or constipation, allergic skin rashes.